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Phospho-VASP (Ser157) Antibody

CAS No.
Chemical Name:
Phospho-VASP (Ser157) Antibody
Synonyms
Phospho-VASP (Ser157) Antibody
CBNumber:
CB65673841
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

Phospho-VASP (Ser157) Antibody Chemical Properties,Uses,Production

Source

Rabbit

Reactivity

Human;Mouse;Rat;Monkey;Guinea Pig

Background

Vasodilator-stimulated phosphoprotein was originally characterized as a substrate of both cGMP- and cAMP-dependent kinases. It is now believed that VASP belongs to the Ena/VASP family of adaptor proteins linking the cytoskeletal system to the signal transduction pathways and that it functions in cytoskeletal organization, fibroblast migration, platelet activation, and axon guidance. Three phosphorylation sites, Ser157, Ser239, and Thr278, have been identified. Ser239 is the major PKG phosphorylation site, while Ser157 is the major PKA phosphorylation site. Evidence suggests that VASP phosphorylation reduces its association with actin and has a negative effect on actin polymerization. Phosphorylation at Ser239 of VASP is a useful marker for monitoring PKG activation and signaling.

References

[1] Butt, E. et al. (1994) J Biol Chem 269, 14509-17.
[2] Ball, L.J. et al. (2000) EMBO J 19, 4903-14.
[3] Machesky, L.M. (2000) Cell 101, 685-8.
[4] Smolenski, A. et al. (1998) J Biol Chem 273, 20029-35.
[5] Harbeck, B. et al. (2000) J Biol Chem 275, 30817-25.
[6] Oelze, M. et al. (2000) Circ Res 87, 999-1005.
[7] Lawrence, D.W. and Pryzwansky, K.B. (2001) J Immunol 166, 5550-6.

Phospho-VASP (Ser157) Antibody Preparation Products And Raw materials

Raw materials

Preparation Products

Phospho-VASP (Ser157) Antibody Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Universal Biotech Co.,Ltd 15921930842 15921930842 yh-wang@univ-bio.com China 25021 58
Enzo Biochem Inc Enzo Biochem Inc. 13797054060 Enzoname@qq.com China 6174 58
Cell Signaling Technology Inc 21-80243558 86218024 info@cellsignal.cn China 6427 58
Abmart Inc 4006-123-828 13162017139 market@ab-mart.com China 6917 58
Tianjin Baibei Biotechnology Co., Ltd. 15302170631 CHINA 6266 58
Guangzhou Leyan Biotechnology Co., Ltd. 15096011602 CHINA 6026 58
Guangzhou Kati Biotechnology Co., Ltd. 13128698830 CHINA 6598 58
Shenzhen Saidjie Technology Co., Ltd. 18899746271 CHINA 6158 58
Hangzhou Shitu Biotechnology Co., Ltd. 17757146756 CHINA 3162 58
Phospho-VASP (Ser157) Antibody
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