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Lamin B1 (D9V6H) Rabbit mAb (HRP Conjugate)

CAS No.
Chemical Name:
Lamin B1 (D9V6H) Rabbit mAb (HRP Conjugate)
Synonyms
Lamin B1 (D9V6H) Rabbit mAb (HRP Conjugate)
CBNumber:
CB66259932
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

Lamin B1 (D9V6H) Rabbit mAb (HRP Conjugate) Chemical Properties,Uses,Production

Description

This antibody is conjugated to the carbohydrate groups of horseradish peroxidase (HRP) via its amine groups. The HRP conjugated antibody is expected to exhibit the same species cross-reactivity as the unconjugated Lamin B1 (D9V6H) Rabbit mAb.

Source

Rabbit

Reactivity

Human;Mouse;Rat

Background

Lamins are nuclear membrane structural components that are important in maintaining normal cell functions, such as cell cycle control, DNA replication, and chromatin organization. Lamins have been subdivided into types A and B. Type-A lamins consist of lamin A and C, which arise from alternative splicing of the lamin A gene LMNA. Lamin A and C are cleaved by caspases into large and small fragments, which can be used as markers for apoptosis. Type-B lamins consist of lamin B1 and B2, encoded by separate genes. Lamin B1 is also cleaved by caspases during apoptosis. Research studies have shown that duplication of the lamin B1 gene LMNB1 is correlated with pathogenesis of the neurological disorder adult-onset leukodystrophy.

References

[1] Gruenbaum, Y. et al. (2000) J Struct Biol 129, 313-23.
[2] Goldberg, M. et al. (1999) Crit Rev Eukaryot Gene Expr 9, 285-93.
[3] Yabuki, M. et al. (1999) Physiol Chem Phys Med NMR 31, 77-84.
[4] Rao, L. et al. (1996) J Cell Biol 135, 1441-55.
[5] Orth, K. et al. (1996) J Biol Chem 271, 16443-6.
[6] Biamonti, G. et al. (1992) Mol Cell Biol 12, 3499-506.
[7] Lin, F. and Worman, H.J. (1995) Genomics 27, 230-6.
[8] Pollard, K.M. et al. (1990) Mol Cell Biol 10, 2164-75.
[9] Chandler, J.M. et al. (1997) Biochem J 322 ( Pt 1), 19-23.
[10] Padiath, Q.S. et al. (2006) Nat Genet 38, 1114-23.

Lamin B1 (D9V6H) Rabbit mAb (HRP Conjugate) Preparation Products And Raw materials

Raw materials

Preparation Products

Lamin B1 (D9V6H) Rabbit mAb (HRP Conjugate) Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Universal Biotech Co.,Ltd 15921930842 15921930842 yh-wang@univ-bio.com China 25021 58
Cell Signaling Technology Inc 21-80243558 86218024 info@cellsignal.cn China 6427 58
Hangzhou Novas Biotechnology Co., Ltd. 15264006066 CHINA 1844 58
Shanghai Haoye Biotechnology Co., Ltd. 15121098156 CHINA 6534 58
Guangzhou Jinling Biotechnology Co., Ltd. 15017560539 CHINA 6140 58
Guangzhou Bingheng Biotechnology Co., Ltd. 13631342304 CHINA 6888 58
Lamin B1 (D9V6H) Rabbit mAb (HRP Conjugate)
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