1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE
- CAS No.
- 13078-13-2
- Chemical Name:
- 1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE
- Synonyms
- TIMTEC-BB SBB003158;N-(M-Tolyl)piperazine diHCl;1-(M-TOLYL)PIPERAZINE DI HCL;M-TOLYLPIPERAZINE HYDROCHLORIDE;N-(3-Methylphenyl)piperazinedi2HCl;1-(m-Tolyl)piperazine hydrochloride;N-(M-TOLYL)PIPERAZINE DIHYDROCHLORIDE;1-(M-TOLYL)PIPERAZINE DIHYDROCHLORIDE;1-(3-Methylphenyl)piperazine dihydrochloride;N-(3-Methylphenyl)piperazine dihydrochloride
- CBNumber:
- CB6675567
- Molecular Formula:
- C11H16N2.2ClH
- Molecular Weight:
- 249.18
- MDL Number:
- MFCD00035284
- MOL File:
- 13078-13-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1-M-TOLYL-PIPERAZINE, DIHYDROCHLORIDE AldrichCPR | R261858 | 50MG | $28.6 |
| N-(m-Tolyl)piperazine Dihydrochloride >96.0%(T) | T1310 | 10g | $192 |
| N-(m-Tolyl)piperazine Dihydrochloride | NAA07813 | 25g | $1260.75 |
| N-(m-Tolyl)piperazine Dihydrochloride | NAA07813 | 50g | $1754 |
| N-(m-Tolyl)piperazine diHCl 95% | AS214226 | 1g | $97 |
| Melting point | 195-202 °C |
|---|---|
| form | powder to crystal |
| color | White to Almost white |
| CAS DataBase Reference | 13078-13-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 36/37/38-24-22 | |||||||||
| Safety Statements | 45-36/37/39-26 | |||||||||
| HS Code | 2933.59.8000 | |||||||||
| NFPA 704 |
|
1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R261858 | 1-M-TOLYL-PIPERAZINE, DIHYDROCHLORIDE AldrichCPR | 13078-13-2 | 50MG | $28.6 | 2023-06-20 | Buy |
| TCI Chemical | T1310 | N-(m-Tolyl)piperazine Dihydrochloride >96.0%(T) | 13078-13-2 | 10g | $192 | 2024-03-01 | Buy |
| Biosynth | NAA07813 | N-(m-Tolyl)piperazine Dihydrochloride | 13078-13-2 | 25g | $1260.75 | 2026-06-04 | Buy |
| Biosynth | NAA07813 | N-(m-Tolyl)piperazine Dihydrochloride | 13078-13-2 | 50g | $1754 | 2026-06-04 | Buy |
| Activate Scientific | AS214226 | N-(m-Tolyl)piperazine diHCl 95% | 13078-13-2 | 1g | $97 | 2026-06-04 | Buy |
1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE Chemical Properties,Uses,Production
Uses
1-(3-methylphenyl)piperazine dihydrochloride is a piperazine derivative and can be used as a pharmaceutical intermediate.
Synthesis
In a 100 ml flask, diethanolamine (10 g) was dissolved in chloroform (40 ml), and a chloroform (20 ml) solution of dichlorosulfoxide (2.6 ml) was added slowly and dropwise at room temperature. Reacted for 7h, the reaction was complete, spun dry, chloroform was added additionally, spun dry again and the dichlorosulfoxide was evaporated to dryness. It was dried to give 14 g of white solid (-chloroethyl)amine hydrochloride in 85% yield, mp: 214.1-215.2C (literature value > 215-216C).
1.58g (10mmol) of IX was added to 10ml of n-butanol with 1mol of aniline derivative and reacted at 180C for 30min in microwave. at the end of the reaction it was allowed to stand and cooled to precipitate crystals. The filter cake was washed with a small amount of dichloromethane and dried under vacuum to obtain white crystals of 1-(3-methylphenyl)piperazine dihydrochloride in 45-54% yield.
1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE Preparation Products And Raw materials
1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
| GLR Innovations | -- | info@glrgroup.in | India | 4535 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; +86-85511178 | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49895 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11598 | 64 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
1-(3-METHYLPHENYL)PIPERAZINE DIHYDROCHLORIDE HYDRATE Spectrum
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