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ChemicalBook >> CAS DataBase List >>IGF-1 LR3

IGF-1 LR3

CAS No.
946870-92-4
Chemical Name:
IGF-1 LR3
Synonyms
LR3-IGF1;IGF LR3-1;KL80;CL281;IGF-1 LR3;IDF-1 LR3;IGF-1Lr3 Igtropin;IGF-1 LR3 0.1mg /1mg;LR3-IGF1 (100mcg/vial;Long R3-IGF-1 (LR3 IGF-I)
CBNumber:
CB6947862
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
MSDS File:
SDS
Last updated:2026-07-22 15:57:46
Product description Number Pack Size Price
DNA (Human Insulin-like growth factor I (LR3 IGF-1, long chain R3) gene) ≥95%(SDS-PAGE&HPLC) AA01FVYQ 1mg $260
More product size

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P305+P351+P338

IGF-1 LR3 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA01FVYQ DNA (Human Insulin-like growth factor I (LR3 IGF-1, long chain R3) gene) ≥95%(SDS-PAGE&HPLC) 946870-92-4 1mg $260 2026-05-30 Buy
Product number Packaging Price Buy
AA01FVYQ 1mg $260 Buy

IGF-1 LR3 Chemical Properties,Uses,Production

Mechanism of action

IGF-1 LR3 binds to cell receptors in the muscle cells and activates cell communication, which then improves the growth rate of muscles.IGF-1 LR3 obstructs the movement of glucose into the body’s cells. This facilitates fat burning and the use of fat in the body for the production of energy. IGF-1 LR3 has a life in the body for about 20-30 hours and therefore enhance the growth amount of muscle for a whole day.

Structure

IGF-1 LR3 is a recombinant synthetic growth factor of ~9.1 kDa, a single polypeptide chain containing 83 amino acid residues. It is an analog of IGF-1 comprised of the complete IGF-1 sequence, with an Arginine substitution for the third position Glutamic acid and a 13 amino acid length N terminus peptide extension. It has been engineered for higher biological potency in vitro, with an increased half-life. This recombinant IGF-1 LR3 product is a highly potent growth factor ideal for stem cell research and cell manufacturing applications, including cells of the ectoderm linage (oligodendrocytes, motor neurons) and mesoderm linage (osteocytes, chondrocytes, and muscle cells).

Description

Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). It differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence ("arginine 3"), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN) ("long"), for a total of 83 amino acids (relative to the 70 of IGF-1).

Uses

The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability.As a result, it is approximately three times more potent than IGF-1,and possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1's half-life of about 12–15 hours).

benefits

Based on the literature, IGF1-LR3 has been shown to:
Increase Fat Loss
Aid in the development of lean muscle mass
Add protection against muscle wasting
Reduce inflammation

Side effects

Some possible side effects of IGF-1 LR3 may include the following: muscle and joint pain, nausea, headaches, hypoglycemia (usually when IGF-1 LR3 is administered in continuous high doses) and may be associated with increased risk of developing some cancers.

IGF-1 LR3 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 106)Suppliers
Supplier Tel Email Country ProdList Advantage
Deepharma
+86-18072861291 +1-7372336996 eason@deefarma.com China 29 58
Shandong Hanjiang Chemical Co., Ltd
+86-0533-2066820 +8618369939125 hanson@sdhanjiang.com China 1000 58
Strong peptide cross-border e-commerce Co. LTD
+undefined13930052870 qt01@qiangtaipharm.com China 84 58
Huaian Banting Trading Co., Ltd.
+8615833979905 sales2@bantingpeptide.com China 85 58
Shanghai Longyu Biotechnology Co., Ltd.
info@longyupharma.com China 2430 58
Hebei Jiafan Trading Company Limited
+86-15354498258; +8615354498258 sales01@jiafan88.com China 208 58
Hainan Fubai Trading Co., LTD
+852-70284493 +852-70284493 13313004729@163.com China 103 58
Hydebio Labs Co.,Limited
+86-18100690299 +86-18100690299 mrkt@hydebiolabs.com China 111 58
Hebei Dangtong Import and export Co LTD
+86-86-4001020630 +8619831957301 admin@hbdangtong.com China 999 58
Hangzhou ICH Biofarm Co., Ltd
+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 1006 58

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Related Qustion

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Q:Can IGF-1 LR3 be used to promote fetal growth?STAR - Feb 25,2026
A:No. IGF-1 LR3 is an insulin-like growth factor-1 (IGF-1) analogue exhibiting low affinity for IGF-binding proteins and high affinity for the IGF-1 receptor. IGF-1, an important foetal growth hormone, is considered a potential therapeutic agent for intrauterine growth restriction. Pregnancy complications, such as placental insufficiency, can lead to foetal growth restriction (FGR), characterised by reduced circulating IGF-1 and insulin concentrations alongside diminished glucose-stimulated insulin secretion (GSIS), potentially causing neonatal glucose dysregulation. Studies indicate that direct intra-circulatory administration of IGF-1 LR3 to growth-restricted foetal lambs fails to improve foetal growth or attenuate circulating insulin or GSIS. This is attributed to IGF-1 LR3 treatment reducing circulating amino acid levels, particularly branched-chain amino acids, which have been demonstrated to enhance GSIS and protein synthesis, thereby supporting foetal growth.

View Lastest Price from IGF-1 LR3 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
IGF-1LR3 pictures 2026-07-22 IGF-1LR3
946870-92-4
$5.00 1Box 99.99% 20000 boxes Hebei Jiafan Trading Company Limited
IGF-1LR3 pictures 2026-07-22 IGF-1LR3
946870-92-4
$5.00 1Box 99.9% 10000000 Hebei Jiafan Trading Company Limited
IGF-1LR3 pictures 2026-07-22 IGF-1LR3
946870-92-4
$5.00 1Box 99.99% 20000 boxes Hebei Jiafan Trading Company Limited
  • IGF-1LR3 pictures
  • IGF-1LR3
    946870-92-4
  • $5.00
  • 99.99%
  • Hebei Jiafan Trading Company Limited
  • IGF-1LR3 pictures
  • IGF-1LR3
    946870-92-4
  • $5.00
  • 99.9%
  • Hebei Jiafan Trading Company Limited
  • IGF-1LR3 pictures
  • IGF-1LR3
    946870-92-4
  • $5.00
  • 99.99%
  • Hebei Jiafan Trading Company Limited
IGF-1 LR3 CL281 IGF-1Lr3 Igtropin LR3-IGF1 (100mcg/vial IDF-1 LR3 Recombinant Human Insulin-like Growth Factor-1 LR3, rhIGF-1 LR3-IGF1, LR3-IGF-1, IGF1 Recombinant Human Insulin-like Growth Factor LR3, rhIGF-1 IGF-1 LR3 0.1mg /1mg KL80 Long R3-IGF-1 (LR3 IGF-I) IGF LR3-1 LR3-IGF1 Recombinant human long-acting insulin-like growth factor rhIGF-1 946870-92-4
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