3-Chloro-6-iodopyridazine
- CAS No.
- 135034-10-5
- Chemical Name:
- 3-Chloro-6-iodopyridazine
- Synonyms
- SW-116;SWF-116;3-Chloro-6-pyrazine;3-Chloro-6-iodopyridazine;3-Chloro-6-iodo-1,2-diazine;Pyridazine, 3-chloro-6-iodo-;3-Chloro-6-iodopyridazine,97%;3-
Chloro- 6- iodopyridazine;3-Chloro-6-iodopyridazine ISO 9001：2015 REACH;3-Chloro-6-iodopyridazine Pyridazine, 3-chloro-6-iodo-
- CBNumber:
- CB71180395
- Molecular Formula:
- C4H2ClIN2
- Molecular Weight:
- 240.43
- MDL Number:
- MFCD08275187
- MOL File:
- 135034-10-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-Chloro-6-iodopyridazine | KOB0085 | 1 g | $191 |
| 3-Chloro-6-iodopyridazine 99% | OR60058 | 1g | $21 |
| 3-Chloro-6-iodopyridazine 99% | OR60058 | 5g | $24 |
| 3-Chloro-6-iodopyridazine 97% | AS30845 | 1g | $23 |
| 3-Chloro-6-iodopyridazine 99% | OR60058 | 25g | $71 |
| More product size | |||
| Melting point | 118-120° |
|---|---|
| Boiling point | 327.7±22.0 °C(Predicted) |
| Density | 2.187±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | -1.18±0.10(Predicted) |
| form | Solid |
| Appearance | White to light brown Solid |
| Water Solubility | Slightly soluble in water. |
| InChI | InChI=1S/C4H2ClIN2/c5-3-1-2-4(6)8-7-3/h1-2H |
| InChIKey | PNEPCDPKMXJYIQ-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NN=C(I)C=C1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933998090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| NFPA 704 |
|
3-Chloro-6-iodopyridazine price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | KOB0085 | 3-Chloro-6-iodopyridazine | 135034-10-5 | 1 g | $191 | 2026-04-30 | Buy |
| Apolloscientific | OR60058 | 3-Chloro-6-iodopyridazine 99% | 135034-10-5 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR60058 | 3-Chloro-6-iodopyridazine 99% | 135034-10-5 | 5g | $24 | 2026-06-04 | Buy |
| Activate Scientific | AS30845 | 3-Chloro-6-iodopyridazine 97% | 135034-10-5 | 1g | $23 | 2026-06-04 | Buy |
| Apolloscientific | OR60058 | 3-Chloro-6-iodopyridazine 99% | 135034-10-5 | 25g | $71 | 2026-06-04 | Buy |
3-Chloro-6-iodopyridazine Chemical Properties,Uses,Production
Uses
3-Chloro-6-iodopyridazine is a reactant in the Suzuki-Miyaura coupling reaction as well as a reactant in the synthesis of 6-Chloropyridazine-3-carbonitrile (C368635).
Synthesis
141-30-0
135034-10-5
The general procedure for the synthesis of 3-chloro-6-iodopyridazine from 3,6-dichloropyridazine was as follows: the intermediate (E)-3-{3-[3'-(1-adamantyl)-4'-hydroxyphenyl]-6-pyridazinyl}-2-propenoic acid ethyl ester was prepared as follows. a) Synthesis of 3-chloro-6-iodopyridazine. Followed the method reported in the literature (Goodman, A.J. et al., Tetrahedron, 1999, 55, 15067-15070). A suspension of 3,6-dichloropyridazine (5.000 g, 33.56 mmol), NaI (6.75 g, 45.0 mmol), and HI (55% to 58%, 25 mL) was stirred for 23 h at 44 °C (oil bath) under argon protection. After completion of the reaction, the mixture was cooled to room temperature and quenched with concentrated HCl. Subsequently, the pH was adjusted to 12 with NaOH, stirred for 10 min and extracted with CH2Cl2. The organic phase was washed with water and dried. The solvent was removed under reduced pressure to give 7.96 g (98% yield) of 3-chloro-6-iodopyridazine as a light yellow solid with a melting point of 114-116 °C (literature value: 110-112 °C). 1H NMR (CDCl3) δ 7.23 (d, J = 8.7 Hz, 1H, 4-ArH), 7.84 ppm (d, J = 8.7 Hz, 1H, 5-ArH).
References
[1] Patent: US2010/4443, 2010, A1. Location in patent: Page/Page column 34
[2] Patent: WO2011/79305, 2011, A1. Location in patent: Page/Page column 41
[3] Journal of Medicinal Chemistry, 2011, vol. 54, # 11, p. 3793 - 3816
[4] Tetrahedron, 1999, vol. 55, # 52, p. 15067 - 15070
[5] Patent: US2005/234046, 2005, A1. Location in patent: Page/Page column 66
3-Chloro-6-iodopyridazine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20120 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2994 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| Zhengzhou Alfa Chemical Co.,Ltd | +86-18530059196 | sale04@alfachem.cn | China | 9612 | 58 |
View Lastest Price from 3-Chloro-6-iodopyridazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-09 | 3-Chloro-6-iodopyridazine
135034-10-5
|
$1.00-200.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-11-18 | 3-Chloro-6-iodopyridazine
135034-10-5
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2022-01-26 | 3-Chloro-6-iodopyridazine
135034-10-5
|
1KG | 97.4% | 100 tons | Honest Joy Holdings Limited
|
-
- 3-Chloro-6-iodopyridazine
135034-10-5
- $1.00-200.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3-Chloro-6-iodopyridazine
135034-10-5
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-Chloro-6-iodopyridazine
135034-10-5
- $0.00
- 97.4%
- Honest Joy Holdings Limited
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