1,2,4-Triazolo[3,4-b]benzothiazol-3-amine, 5,8-dimethoxy-
![1,2,4-Triazolo[3,4-b]benzothiazol-3-amine, 5,8-dimethoxy- Structure](CAS/20210305/GIF/943119-42-4.gif)
- CAS No.
- 943119-42-4
- Chemical Name:
- 1,2,4-Triazolo[3,4-b]benzothiazol-3-amine, 5,8-dimethoxy-
- Synonyms
- OUL232;OUL232, 10 mM in DMSO;1,2,4-Triazolo[3,4-b]benzothiazol-3-amine, 5,8-dimethoxy-;5,8-Dimethoxybenzo[4,5]thiazolo[2,3-c][1,2,4]triazol-3-amine
- CBNumber:
- CB712876959
- Molecular Formula:
- C10H10N4O2S
- Molecular Weight:
- 250.28
- MDL Number:
- MOL File:
- 943119-42-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| OUL232 99.86% | CS-0636592 | 5mg | $195 |
| OUL232 99.86% | CS-0636592 | 10mg | $292 |
| OUL232 99.86% | CS-0636592 | 25mg | $526 |
| OUL232 99.86% | CS-0636592 | 50mg | $791 |
| OUL232 99.86% | CS-0636592 | 100mg | $1051 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
1,2,4-Triazolo[3,4-b]benzothiazol-3-amine, 5,8-dimethoxy- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0636592 | OUL232 99.86% | 943119-42-4 | 5mg | $195 | 2026-06-04 | Buy |
| ChemScene | CS-0636592 | OUL232 99.86% | 943119-42-4 | 10mg | $292 | 2026-06-04 | Buy |
| ChemScene | CS-0636592 | OUL232 99.86% | 943119-42-4 | 25mg | $526 | 2026-06-04 | Buy |
| ChemScene | CS-0636592 | OUL232 99.86% | 943119-42-4 | 50mg | $791 | 2026-06-04 | Buy |
| ChemScene | CS-0636592 | OUL232 99.86% | 943119-42-4 | 100mg | $1051 | 2026-06-04 | Buy |
1,2,4-Triazolo[3,4-b]benzothiazol-3-amine, 5,8-dimethoxy- Chemical Properties,Uses,Production
Uses
OUL232 is a potent inhibitor of mono-ARTs PARP7, PARP10, PARP11, PARP12, PARP14, and PARP15. OUL232 is the most potent PARP10 inhibitor described to date (IC50=7.8 nM), as well as the first PARP12 inhibitor ever reported[1].
IC 50
PARP7: 83 nM (IC50); PARP10: 7.8 nM (IC50); PARP14: 300 nM (IC50); PARP15: 56 nM (IC50); PARP1: 15 μM (IC50); PARP2: 10 μM (IC50); PARP3: 50 μM (IC50); PARP4: 11 μM (IC50); TNKS1: 5.4 μM (IC50); TNKS2: 10 μM (IC50); PARP11: 240 nM (IC50); PARP12: 160 nM (IC50); PARP16: 3.4 μM (IC50)
References
[1] Murthy S, et al. [1,2,4]Triazolo[3,4-b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes. J Med Chem. 2023 Jan 4. DOI:10.1021/acs.jmedchem.2c01460
1,2,4-Triazolo[3,4-b]benzothiazol-3-amine, 5,8-dimethoxy- Preparation Products And Raw materials
Raw materials
Preparation Products
1,2,4-Triazolo[3,4-b]benzothiazol-3-amine, 5,8-dimethoxy- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai Haozhixiang Biotechnology Co., Ltd | 526763801 13301653310 | 526763801@qq.com | China | 9554 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 13636370518 | shyysw007@163.com | China | 89686 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9748 | 55 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9625 | 58 |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 9781 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 4334 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4997 | 58 |
| Hubei wei shi reagent group ltd., company | 027-59102966 18717199209 | 2853877583@qq.com | China | 2907 | 58 |
