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1,3,5-Tri-O-benzoyl-D-ribofuranose

1,3,5-Tri-O-benzoyl-D-ribofuranose structure

CAS No.: 22224-41-5

Chemical Name:: 1,3,5-Tri-O-benzoyl-D-ribofuranose

Synonyms: Clofarabine Impurity 5;1,3,5-Bz-D-ribofuranose;1,3,5-tri-benzoyl-α-D-ribose;Clofarabine intermediate (III);1,3,5-tri-O-Benzoyl-alpha-D-Ri;1,3,5-TRIBENZOYL-A-D-RIBOFURANOSE;1,3,5-Tribenzoyl-α-D-ribofuranose;1,3,5-Tri-O-benzoyl-D-ribofuranose;1,3,5-Tribenzoate-α-D-Ribofuranose;1,3,5-tribenzoate-a-D-Ribofuranose

CBNumber:: CB7138063

Molecular Formula:: C26H22O8

Molecular Weight:: 462.45

MDL Number:: MFCD00080818

MOL File:: 22224-41-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:16:29

Product description	Number	Pack Size	Price
α-D-Ribofuranose 1,3,5-tribenzoate 97%	389080	5g	$93.3
1,3,5-Tri-O-benzoyl-α-D-ribofuranose >97.0%(HPLC)	T2641	5g	$56
1,3,5-Tri-O-benzoyl-α-D-ribofuranose >97.0%(HPLC)	T2641	25g	$193
1,3,5-Tri-O-benzoyl-a-D-ribofuranose	TRC-B209535-50G	50g	$205
1,3,5-Tri-O-benzoyl-a-D-ribofuranose	MT04028	5g	$150
More product size

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1,3,5-Tri-O-benzoyl-D-ribofuranose Properties

Melting point	125-129 °C(lit.)
Boiling point	629.6±55.0 °C(Predicted)
Density	1.37±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
pka	12.35±0.70(Predicted)
form	Powder
color	Pale brown
optical activity	[α]20/D +85.0°, c = 1 in chloroform
Water Solubility	Insoluble in water, easily soluble in chloroform.
λmax	273nm(MeOH)(lit.)
BRN	98446
InChIKey	HUHVPBKTTFVAQF-QFBXJQHPSA-N
SMILES	O(C(=O)C1=CC=CC=C1)C1O[C@H](COC(=O)C2=CC=CC=C2)[C@@H](OC(=O)C2=CC=CC=C2)[C@H]1O \|&1:11,22,32,r\|
CAS DataBase Reference	22224-41-5(CAS DataBase Reference)
UNSPSC Code	12352201
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H319-H335-H351b

Precautionary statements

P261-P264b-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362+P364-P403+P233-P501c

PPE

Eyeshields, Gloves, type N95 (US)

Safety Statements

22-24/25

WGK Germany

HS Code

29400090

Storage Class

11 - Combustible Solids

NFPA 704

	1
0		0

1,3,5-Tri-O-benzoyl-D-ribofuranose price More Price(92)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	389080	α-D-Ribofuranose 1,3,5-tribenzoate 97%	22224-41-5	5g	$93.3	2023-06-20	Buy
TCI Chemical	T2641	1,3,5-Tri-O-benzoyl-α-D-ribofuranose >97.0%(HPLC)	22224-41-5	5g	$56	2026-04-30	Buy
TCI Chemical	T2641	1,3,5-Tri-O-benzoyl-α-D-ribofuranose >97.0%(HPLC)	22224-41-5	25g	$193	2026-04-30	Buy
TRC	TRC-B209535-50G	1,3,5-Tri-O-benzoyl-a-D-ribofuranose	22224-41-5	50g	$205	2026-06-03	Buy
Biosynth	MT04028	1,3,5-Tri-O-benzoyl-a-D-ribofuranose	22224-41-5	5g	$150	2026-06-04	Buy

Product number	Packaging	Price	Buy
389080	5g	$93.3	Buy
T2641	5g	$56	Buy
T2641	25g	$193	Buy
TRC-B209535-50G	50g	$205	Buy
MT04028	5g	$150	Buy

1,3,5-Tri-O-benzoyl-D-ribofuranose Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Uses

Starting material for nucleosides.

Uses

It is employed as a starting material for nucleosides and is an intermediate fir cloforabine.

Synthesis

beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate

6974-32-9

22224-41-5

Synthesis of compound vi: Compound v (2.57 mmol) was dissolved in 26 mL of anhydrous dichloromethane, and the reaction lasted for 2.5 h under the condition of ice-water bath with slow passage of dry HCl gas. After completion of the reaction, the reaction solution was washed with 19.5 mL of ice water and the organic layer was separated. The organic layer was washed sequentially with saturated sodium bicarbonate solution until the aqueous layer was weakly basic, and then washed with ice water until the aqueous layer was neutral. The organic layer was dried with anhydrous sodium sulfate for more than 4 hours and subsequently concentrated under reduced pressure to give a light yellow syrupy product. The syrup was recrystallized using a solvent mixture of hexane and dichloromethane to give the white solid compound vi in 65.1% yield.1H NMR (CDCl3) δ ppm: 7.36-8.14 (m, 15H, OBz), 6.68 (d, J = 4.4 Hz, 1H, H-1), 5.59 (dd, 1H, H-3), 4.64-4.80 ( m, 4H, H-2, H-4 and H-5). Melting point: 139-140°C.

References

[1] Patent: EP2177527, 2010, A1. Location in patent: Page/Page column 11
[2] Journal of Organic Chemistry, 1985, vol. 50, # 14, p. 2597 - 2598

1,3,5-Tri-O-benzoyl-D-ribofuranose Preparation Products And Raw materials

Raw materials

beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate Dichloromethane Hydrochloric acid

Preparation Products

3',5'-DI-O-BENZOYL-5-FLUORO-2'-O-METHYLURIDINE

1,3,5-Tri-O-benzoyl-D-ribofuranose Suppliers

Global( 310)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21585	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29812	58
Zhejiang ZETian Fine Chemicals Co. LTD	18957127338	stella@zetchem.com	China	2994	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114	sales@amoychem.com	China	6366	58
Nanjing Baifuli Technology Co., Ltd.	+86-15335185688	sales@unisyn.cn	CHINA	332	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49979	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Jinan Carbotang Biotech Co.,Ltd.	58
Xiamen AmoyChem Co., Ltd	58
Nanjing Baifuli Technology Co., Ltd.	58
Standardpharm Co. Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
Antai Fine Chemical Technology Co.,Limited	58

View Lastest Price from 1,3,5-Tri-O-benzoyl-D-ribofuranose manufacturers

Update time	Product	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-06	1,3,5-Tri-O-benzoyl-D-ribofuranose 22224-41-5	100g	97%min	10000g	WUHAN FORTUNA CHEMICAL CO., LTD
2026-05-11	1,3,5-Tri-O-benzoyl-D-ribofuranose 22224-41-5			10g	TargetMol Chemicals Inc.
2025-04-04	1,3,5-Tri-O-benzoyl-D-ribofuranose 22224-41-5	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

1,3,5-Tri-O-benzoyl-D-ribofuranose
22224-41-5
97%min
WUHAN FORTUNA CHEMICAL CO., LTD

1,3,5-Tri-O-benzoyl-D-ribofuranose
22224-41-5
TargetMol Chemicals Inc.

1,3,5-Tri-O-benzoyl-D-ribofuranose
22224-41-5
98%
Henan Aochuang Chemical Co.,Ltd.

1,3,5-Tri-O-benzoyl-D-ribofuranose Spectrum

1,3,5-Tri-O-benzoyl-D-ribofuranose(22224-41-5)¹HNMR 1,3,5-Tri-O-benzoyl-D-ribofuranose(22224-41-5)IR 1,3,5-Tri-O-benzoyl-D-ribofuranose(22224-41-5)FT-IR 1,3,5-Tri-O-benzoyl-D-ribofuranose(22224-41-5)Raman

22224-41-5(1,3,5-Tri-O-benzoyl-D-ribofuranose)Related Search:

Denatonium Benzoate Anhydrous Dibenzofuran Emamectin benzoate Benzoyl peroxide Sodium benzoate

Benzoyl chloride Benzyl benzoate Benzofuran Sofosbuvir alpha-D-erythro-Pentofuranous-2-ulose 1,3,5-tribenzoate

Sofosbuvir Impurity26 SofosBuvir Impurity 2 1-((2S,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione sofosBuvir Impurity 33 sofosBuvir impurity 49

SofosBuvir Impurity 55 Sofosbuvir Impurity 84 PSI 7411

1of4

1,3,5-TRI-O-BENZOYL-ALPHA-D-RIBOFURANOSE 1,3,5-TRI-O-BENZOYL-ALPHA-D-RIBOFURANOSIDE 1,3,5-Tri-O-benzoyl-D-ribofuranose 1,3,5-TRIBENZOATE-ALPHA-D-RIBOFURANOSE [5-(benzoyloxy)-2-(benzoyloxymethyl)-4-hydroxyoxolan-3-yl] benzoate ALPHA-D-RIBOFURANOSE 1,3,5-TRIBENZOATE α-D-Ribofuranose, 1,3,5-tribenzoate a-D-Ribofuranose, 1,3,5-tribenzoate 1,3,5-Tri-O-Benzoyl-A-D-Ribofuranose 1,3,5-TRIBENZOYL-A-D-RIBOFURANOSE 1,3,5-Tri-O-Benzoyl-alpha-D-Ribofuranose(a-D-Ribofluranose-1,3,5-Tribenzoate) Clofarabine intermediate (III) 1,3,5-TRI-O-BENZOYL-ALPHA-D-RIBOFURANOSE 98% 1,3,5-Tribenzoate-α-D-Ribofuranose 1,3,5-Tribenzoyl-α-D-ribofuranose 1,3,5-Tri-O-benzoyl-α-D-ribofuranose ,98% 1,3,5-tribenzoate-a-D-Ribofuranose 1,3,5-Tribenzoyl-alpha-D-ribofuranose 1,3,5-Tri-O-Benzoyl-alpha-D-Ribofuranose Min98% C2 PR-002 1,3,5-Tri-O-benzoyl-D-ribofuranose 1,3,5-Tri-O-benzoyl-D-ribofuranose (Decitabine) 1,3,5-Tri- O -benzoyl-α-D-ribofuranoside 1,3,5-tri-O-Benzoyl-alpha-D-Ri 1,3,5-tri-benzoyl-α-D-ribose 1,3,5-Tri-O-benzoyl-alpha-D-ribofuranose, 97% pale brown powder 1,3,5- three -O- benzoyl -a-D- furan ribos [(2R,3S,4R,5R)-3,5-dibenzoyloxy-4-hydroxy-tetrahydrofuran-2-yl]methyl benzoate [3,5-BIS(BENZOYLOXY)-4-HYDROXYOXOLAN-2-YL]METHYL BENZOATE 1,3,5-Bz-D-ribofuranose Clofarabine Impurity 5 1,3,5-tribenzoyl - α - d-ribofuran 1，3，5-Tri-O-benzoyl-α-D-ribofuranose 1,3,5-Tri-O-benzoyl-D-ribofuranose USP/EP/BP (2R,3S,4R)-3,5-bis(benzoyloxy)-4-hydroxyoxolan-2-yl]methyl benzoate [(2R,5R)-3,5-dibenzoyloxy-4-hydroxyoxolan-2-yl]methyl benzoate α-D-Ribofuranose 1,3,5-tribenzoate α-D-Ribofuranose, 1,3,5-tribenzoate (6CI, 9CI, ACI) 1,3,5-tribenzoyl- α- D-furan ribose 1,3,5-Tri-O-benzoyesl-α-D-ribofuranose α-D-Ribofuranose 1,3,5-tribenzoate 22224-41-5 222224-41-5 C26H22O8 Carbohydrate Synthesis Specialty Synthesis Monosaccharides API intermediates (intermediate of clofarabine) Sugars, Carbohydrates & Glucosides 22224-41-5

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1,3,5-Tri-O-benzoyl-D-ribofuranose

1,3,5-Tri-O-benzoyl-D-ribofuranose Properties

SAFETY

Risk and Safety Statements

1,3,5-Tri-O-benzoyl-D-ribofuranose price More Price(92)

1,3,5-Tri-O-benzoyl-D-ribofuranose Chemical Properties,Uses,Production

Chemical Properties

Uses

Uses

Synthesis

References

1,3,5-Tri-O-benzoyl-D-ribofuranose Preparation Products And Raw materials

Raw materials

Preparation Products

1,3,5-Tri-O-benzoyl-D-ribofuranose Suppliers

View Lastest Price from 1,3,5-Tri-O-benzoyl-D-ribofuranose manufacturers

1,3,5-Tri-O-benzoyl-D-ribofuranose Spectrum

22224-41-5(1,3,5-Tri-O-benzoyl-D-ribofuranose)Related Search: