Methyl 1,3-benzodioxole-4-carboxylate
- CAS No.
- 33842-16-9
- Chemical Name:
- Methyl 1,3-benzodioxole-4-carboxylate
- Synonyms
- Methyl 1,3-Benzodioxole-4-carboxylate;methyl benzo[d][1,3]dioxole-4-carboxylate;Methyl 2H-benzo[d]1,3-dioxolene-4-carboxylate;Methyl 1,3-Benzodioxole-4-Carboxylate(WX618073);1,3-Benzodioxole-4-carboxylic acid, methyl ester;Benzo[1,3]dioxole-4-carboxylic acid methyl ester
- CBNumber:
- CB71459659
- Molecular Formula:
- C9H8O4
- Molecular Weight:
- 180.16
- MDL Number:
- MFCD01546796
- MOL File:
- 33842-16-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl benzo[d][1,3]dioxole-4-carboxylate | 126642 | 1.00g | $161 |
| Methyl benzo[d][1,3]dioxole-4-carboxylate | 126642 | 5.00g | $440 |
| Methyl benzo[d][1,3]dioxole-4-carboxylate | 126642 | 10.00g | $802 |
| Methyl benzo[d][1,3]dioxole-4-carboxylate 97% | M51645 | 250mg | $22 |
| Methyl benzo[d][1,3]dioxole-4-carboxylate 97% | M51645 | 1g | $27 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS02 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H319-H225 |
| Precautionary statements | P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P403+P235 |
| HS Code | 2932990090 |
Methyl 1,3-benzodioxole-4-carboxylate price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 126642 | Methyl benzo[d][1,3]dioxole-4-carboxylate | 33842-16-9 | 1.00g | $161 | 2026-05-18 | Buy |
| Matrix Scientific | 126642 | Methyl benzo[d][1,3]dioxole-4-carboxylate | 33842-16-9 | 5.00g | $440 | 2026-05-18 | Buy |
| Matrix Scientific | 126642 | Methyl benzo[d][1,3]dioxole-4-carboxylate | 33842-16-9 | 10.00g | $802 | 2026-05-18 | Buy |
| Synthonix | M51645 | Methyl benzo[d][1,3]dioxole-4-carboxylate 97% | 33842-16-9 | 250mg | $22 | 2026-05-06 | Buy |
| Synthonix | M51645 | Methyl benzo[d][1,3]dioxole-4-carboxylate 97% | 33842-16-9 | 1g | $27 | 2026-05-06 | Buy |
Methyl 1,3-benzodioxole-4-carboxylate Chemical Properties,Uses,Production
Synthesis
2411-83-8
74-95-3
33842-16-9
General procedure for the synthesis of methyl benzo[d][1,3]meso-dioxole-4-carboxylate from methyl 2,3-dihydroxybenzoate and dibromomethane: 6.0 g (0.036 mol) of methyl 2,3-dihydroxybenzoate and cesium carbonate (0.54 mol) were dissolved in 50 mL of N,N-dimethylformamide (DMF). 11.5 mL of dibromomethane (0.54 mol) was added slowly and dropwise at room temperature. After the dropwise addition, the temperature of the reaction system was raised to 110 °C and the reaction was maintained at this temperature for 3 hours. After completion of the reaction, the reaction was cooled to room temperature, stopped and filtered. Equal volumes of water and ethyl acetate were added to the filtrate for liquid-liquid separation. The aqueous phase was extracted twice with ethyl acetate, and all organic phases were combined and washed with water and saturated saline in that order. The organic phase was dried with anhydrous sodium sulfate for 8 minutes. The desiccant was removed by filtration, the solvent was removed by evaporation under reduced pressure and the residue was purified by silica gel column chromatography. Petroleum ether: ethyl acetate (6:1, v/v) was used as eluent to collect the target component, and 5.2 g of white solid product was obtained after evaporation under reduced pressure in 81.2% yield.
References
[1] Patent: CN103804341, 2018, B. Location in patent: Paragraph 0064; 0068; 0069
[2] Journal of Medicinal Chemistry, 2004, vol. 47, # 4, p. 871 - 887
[3] Patent: US2004/34046, 2004, A1
[4] Patent: WO2004/4732, 2004, A1. Location in patent: Page/Page column 65-66
[5] Patent: WO2005/34939, 2005, A1. Location in patent: Page/Page column 76
Methyl 1,3-benzodioxole-4-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3998 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49967 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8618662433356 | 3899766280@qq.com | China | 26362 | 58 |
| Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13523716970 | Lingzhiyue@aliyun.com | China | 3145 | 58 |
View Lastest Price from Methyl 1,3-benzodioxole-4-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2024-08-15 | Methyl 1,3-benzodioxole-4-carboxylate
33842-16-9
|
$1.00 | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd |
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- Methyl 1,3-benzodioxole-4-carboxylate
33842-16-9
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
