(4-Trifluoromethyl-pyridin-3-yl)-methanol
- CAS No.
- 198401-76-2
- Chemical Name:
- (4-Trifluoromethyl-pyridin-3-yl)-methanol
- Synonyms
- 4-(Trifluoromethyl)-3-pyridinemethanol;3-Pyridinemethanol, 4-(trifluoromethyl)-;(4-Trifluoromethyl-pyridin-3-yl)-methanol
- CBNumber:
- CB71554077
- Molecular Formula:
- C7H6F3NO
- Molecular Weight:
- 177.12
- MDL Number:
- MFCD10568162
- MOL File:
- 198401-76-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-(Hydroxymethyl)-4-(trifluoromethyl)pyridine 95% | AS45187 | 1g | $518 |
| (4-(Trifluoromethyl)Pyridin-3-Yl)Methanol 98% | AA002BEV | 100mg | $67 |
| (4-(Trifluoromethyl)Pyridin-3-Yl)Methanol 98% | AA002BEV | 250mg | $110 |
| (4-(Trifluoromethyl)Pyridin-3-Yl)Methanol 95% | AA002BEV | 1g | $352 |
| (4-(Trifluoromethyl)Pyridin-3-Yl)Methanol 95% | AA002BEV | 5g | $952 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
(4-Trifluoromethyl-pyridin-3-yl)-methanol price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS45187 | 3-(Hydroxymethyl)-4-(trifluoromethyl)pyridine 95% | 198401-76-2 | 1g | $518 | 2026-06-04 | Buy |
| aablocks | AA002BEV | (4-(Trifluoromethyl)Pyridin-3-Yl)Methanol 98% | 198401-76-2 | 100mg | $67 | 2026-05-28 | Buy |
| aablocks | AA002BEV | (4-(Trifluoromethyl)Pyridin-3-Yl)Methanol 98% | 198401-76-2 | 250mg | $110 | 2026-05-28 | Buy |
| aablocks | AA002BEV | (4-(Trifluoromethyl)Pyridin-3-Yl)Methanol 95% | 198401-76-2 | 1g | $352 | 2026-05-28 | Buy |
| aablocks | AA002BEV | (4-(Trifluoromethyl)Pyridin-3-Yl)Methanol 95% | 198401-76-2 | 5g | $952 | 2026-05-28 | Buy |
(4-Trifluoromethyl-pyridin-3-yl)-methanol Chemical Properties,Uses,Production
Synthesis
175204-82-7
198401-76-2
General procedure for the synthesis of (4-trifluoromethyl-3-pyridine)-methanol from 4-trifluoromethylnicotinic acid methyl ester: 0.37 g (9.7 mmol) of lithium aluminum hydride was dissolved in 100 ml of THF and the solution was cooled down to -50 °C. Subsequently, a solution of 2.0 g (9.8 mmol) of methyl 4-trifluoromethylnicotinate dissolved in 30 ml of THF was added slowly and dropwise. The reaction mixture was stirred continuously at -50 °C for 3 h to ensure complete reaction. Upon completion of the reaction, ethyl acetate was added cautiously and stirred briefly before adding water and continuing to stir. The reaction mixture was separated by vacuum filtration and the filtrate was extracted with ethyl acetate. The organic layer obtained by extraction was washed sequentially with water and aqueous sodium chloride solution and subsequently dried with anhydrous magnesium sulfate. The dried solution was distilled under vacuum to remove the solvent, and the residue was purified by silica gel column chromatography (unfolding agent: hexane-ethyl acetate mixed solvent) to finally obtain 0.6 g (35.3% yield) of (4-trifluoromethylpyridin-3-yl)-methanol as a yellow oil. The product was analyzed by 1H-NMR [CDCl3/TMS, δ (ppm)]: 9.00 (1H, s), 8.73 (1H, d), 7.51 (1H, d), 4.95 (2H, s).
References
[1] Patent: EP1364946, 2003, A1. Location in patent: Page/Page column 200-201
[2] Patent: US2005/256004, 2005, A1. Location in patent: Page/Page column 35
[3] Patent: US5756497, 1998, A
(4-Trifluoromethyl-pyridin-3-yl)-methanol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Golden Pharma Co., Limited | +86-18958062155 | sales@zjgoldpharm.com | China | 5899 | 58 |
| Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 | sales@anikare.com | China | 10000 | 58 |
| Cochemical Co. Ltd. | +86-029-86115547 +86-17791676824 | sales@cochemical.com | China | 3952 | 58 |
| Nanjing Moldeep Biochemical Co., Ltd. | +86-25-58282389 +86-17351037455 | inquiries@moldeep.com | China | 20000 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12740 | 55 | |
| Aloespharm Co., Ltd. | 021-20960837 | market@aloespharm.com | China | 1302 | 55 |
| Cochemical Ltd. | 029-86115547 17791676824 | sales@cochemical.com | China | 3014 | 58 |
198401-76-2((4-Trifluoromethyl-pyridin-3-yl)-methanol)Related Search:
1of4
