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ChemicalBook >> CAS DataBase List >>2-BROMO-4-FLUORO-6-NITROANILINE

2-BROMO-4-FLUORO-6-NITROANILINE

CAS No.
10472-88-5
Chemical Name:
2-BROMO-4-FLUORO-6-NITROANILINE
Synonyms
SKL366;2-BROMO-4-FLUORO-6-NITROANILINE;2-Bromo-4-fluoro-6-nitroaniline98%;2-Bromo-4-fluoro-6-nitroaniline 98%;2-bromo-4-fluoro-6-nitrobenzenamine;2-Bromo-4-fluoro-6-nitroaniline, 97%;2-Amino-3-bromo-5-fluoronitrobenzene;BenzenaMine, 2-broMo-4-fluoro-6-nitro-;2-Bromo-4-fluoro-6-nitroaniline,tech.90%;Benzenebutanoicacid,7-fluoro-α,γ-dioxo-,ethylester
CBNumber:
CB7159910
Molecular Formula:
C6H4BrFN2O2
Molecular Weight:
235.01
MDL Number:
MFCD07779528
MOL File:
10472-88-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:28:51
Product description Number Pack Size Price
2-Bromo-4-fluoro-6-nitroaniline >98.0%(GC) B4872 1g $122
2-Bromo-4-fluoro-6-nitroaniline 97% PC3591 1g $21
2-Bromo-4-fluoro-6-nitroaniline 97% PC3591 5g $28
2-Bromo-4-fluoro-6-nitroaniline 97% PC3591 1g $21
2-Bromo-4-fluoro-6-nitroaniline 97% PC3591 5g $28
More product size

2-BROMO-4-FLUORO-6-NITROANILINE Properties

Melting point 70-72°C
Boiling point 313.9±37.0 °C(Predicted)
Density 1.896±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form Powder
pka -2.32±0.25(Predicted)
color Orange
InChI InChI=1S/C6H4BrFN2O2/c7-4-1-3(8)2-5(6(4)9)10(11)12/h1-2H,9H2
InChIKey HCYDUPDSEDHSQB-UHFFFAOYSA-N
SMILES C1(N)=C([N+]([O-])=O)C=C(F)C=C1Br

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H312-H315-H319-H332-H335
Precautionary statements  P261-P280-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  T
HazardClass  6.1
HS Code  2921420090
NFPA 704
0
2 0

2-BROMO-4-FLUORO-6-NITROANILINE price More Price(66)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B4872 2-Bromo-4-fluoro-6-nitroaniline >98.0%(GC) 10472-88-5 1g $122 2026-04-30 Buy
Apolloscientific PC3591 2-Bromo-4-fluoro-6-nitroaniline 97% 10472-88-5 1g $21 2026-06-04 Buy
Apolloscientific PC3591 2-Bromo-4-fluoro-6-nitroaniline 97% 10472-88-5 5g $28 2026-06-04 Buy
Apolloscientific PC3591 2-Bromo-4-fluoro-6-nitroaniline 97% 10472-88-5 1g $21 2026-06-04 Buy
Apolloscientific PC3591 2-Bromo-4-fluoro-6-nitroaniline 97% 10472-88-5 5g $28 2026-06-04 Buy
Product number Packaging Price Buy
B4872 1g $122 Buy
PC3591 1g $21 Buy
PC3591 5g $28 Buy
PC3591 1g $21 Buy
PC3591 5g $28 Buy

2-BROMO-4-FLUORO-6-NITROANILINE Chemical Properties,Uses,Production

Chemical Properties

off-white powder

Uses

2-Bromo-4-fluoro-6-nitroaniline is used as pharmaceutical intermediate.

Synthesis

4-Fluoro-2-nitrobenzeneamine

364-78-3

2-BROMO-4-FLUORO-6-NITROANILINE

10472-88-5

The general procedure for the synthesis of 2-bromo-4-fluoro-6-nitroaniline from 4-fluoro-2-nitroaniline is as follows: 1. 4-fluoro-2-nitroaniline (10.0 g, 42.55 mmol) was dissolved in dichloromethane (DCM) to prepare a mixture. 2. a mixture of bromine (Br2, 9.9 ml, 130 mmol) in dichloromethane (110 mL, pre-cooled to 0 °C) and acetic acid (HOAc, 75 mL) was slowly added dropwise at 0 °C, with the rate of dropwise acceleration being controlled to keep the internal reaction temperature below 10 °C. 3. After titration, the reaction mixture was stirred at room temperature overnight. 4. The reaction mixture was poured into water (500 mL) to separate the organic phase. 5. The pH of the aqueous phase was adjusted to about 7 with ammonium hydroxide (NH4OH) and then the aqueous phase was extracted with dichloromethane (DCM, 100 mL x 3). 6. The organic extracts were combined, dried with magnesium sulfate (MgSO4), filtered and concentrated in vacuum to give 2-bromo-4-fluoro-6-nitroaniline as a yellow solid (14 g, 93% yield). Mass spectrum (ESI): m/z = 233 [M-1].

References

[1] Patent: US5606063, 1997, A
[2] Patent: WO2013/26914, 2013, A1. Location in patent: Page/Page column 118
[3] Patent: CN108218887, 2018, A. Location in patent: Paragraph 0094; 0097; 0098; 0099
[4] Journal of Antibiotics, 1994, vol. 47, # 12, p. 1456 - 1465
[5] Patent: US2006/229289, 2006, A1. Location in patent: Page/Page column 25

2-BROMO-4-FLUORO-6-NITROANILINE Preparation Products And Raw materials

Global( 159)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20122 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Fuxin Pharmaceutical
+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10000 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58

View Lastest Price from 2-BROMO-4-FLUORO-6-NITROANILINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-BROMO-4-FLUORO-6-NITROANILINE pictures 2025-09-25 2-BROMO-4-FLUORO-6-NITROANILINE
10472-88-5
$1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
2-Bromo-4-fluoro-6-n  pictures 2021-11-15 2-Bromo-4-fluoro-6-n
10472-88-5
$10.00 1KG 99% 500ton/Month Qiuxian Baitai New Material Co., LTD
2-Bromo-4-fluoro-6-nitroaniline  pictures 2020-02-26 2-Bromo-4-fluoro-6-nitroaniline
10472-88-5
1KG 99.0% 100 tons Shaanxi Dideu Medichem Co. Ltd

2-BROMO-4-FLUORO-6-NITROANILINE Spectrum

2-Bromo-4-fluoro-6-nitroaniline 98% 2-Bromo-4-fluoro-6-nitroaniline98% 2-BROMO-4-FLUORO-6-NITROANILINE BenzenaMine, 2-broMo-4-fluoro-6-nitro- 2-bromo-4-fluoro-6-nitrobenzenamine 2-Amino-3-bromo-5-fluoronitrobenzene 2-Bromo-4-fluoro-6-nitroaniline,tech.90% 2-BROMO-4-FLUORO-6-NITROANILINE ISO 9001:2015 REACH SKL366 Benzenebutanoicacid,7-fluoro-α,γ-dioxo-,ethylester 2-Bromo-4-fluoro-6-nitroaniline, 97% 10472-88-5 C6H4BrFN2O2 C6H4BrN2O2 Amines Phenyls & Phenyl-Het
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