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ChemicalBook >> CAS DataBase List >>5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine

5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine

CAS No.
1036027-54-9
Chemical Name:
5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine
Synonyms
5-(TrifluoroMethyl)-7-azaindole;5-TRIFLUOROMETHYL-1H-PYRROLO[2,3-B]PYRIDINE;1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)-;1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)- 5-(TrifluoroMethyl)-7-azaindole
CBNumber:
CB71871817
Molecular Formula:
C8H5F3N2
Molecular Weight:
186.13
MDL Number:
MFCD06659680
MOL File:
1036027-54-9.mol
MSDS File:
SDS
Last updated:2026-05-28 02:43:26
Product description Number Pack Size Price
5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine Aldrich ADE000933 1g $870
5-(TRIFLUOROMETHYL)-1H-PYRROLO[2,3-B]PYRIDINE 97% 50599 1G $166
5-(TRIFLUOROMETHYL)-1H-PYRROLO[2,3-B]PYRIDINE 97% 50599 5G $499
5-(TRIFLUOROMETHYL)-1H-PYRROLO[2,3-B]PYRIDINE 97% 50599 10G $749
5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine 98% PC200224 250mg $21

5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine Properties

Melting point 104-105 °C
Density 1.447±0.06 g/cm3(Predicted)
storage temp. Store at room temperature
form solid
pka 12.82±0.40(Predicted)
color Off-white to light brown
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
RIDADR  2811
WGK Germany  3
HazardClass  6.1
PackingGroup  Ⅲ
HS Code  2933399990

5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich ADE000933 5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine Aldrich 1036027-54-9 1g $870 2026-04-30 Buy
AstaTech 50599 5-(TRIFLUOROMETHYL)-1H-PYRROLO[2,3-B]PYRIDINE 97% 1036027-54-9 1G $166 2026-04-30 Buy
AstaTech 50599 5-(TRIFLUOROMETHYL)-1H-PYRROLO[2,3-B]PYRIDINE 97% 1036027-54-9 5G $499 2026-04-30 Buy
AstaTech 50599 5-(TRIFLUOROMETHYL)-1H-PYRROLO[2,3-B]PYRIDINE 97% 1036027-54-9 10G $749 2026-04-30 Buy
Apolloscientific PC200224 5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine 98% 1036027-54-9 250mg $21 2026-06-04 Buy
Product number Packaging Price Buy
ADE000933 1g $870 Buy
50599 1G $166 Buy
50599 5G $499 Buy
50599 10G $749 Buy
PC200224 250mg $21 Buy

5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine Chemical Properties,Uses,Production

Synthesis

A solution of 3.4 g of 5-trifluoromethyl-3-[(trimethylsilyl)ethynyl]pyridin-2-amine and 2.96 g of potassium tert-butylate in 55 cm3 of N-methylpyrrolidinone is heated at 90 ℃. for three hours. The mixture is cooled to room temperature and then poured slowly into 250 cm3 of water saturated with ammonium chloride. The mixture is diluted with ethyl acetate and filtered, separating the phases into their isomers. The aqueous phase is extracted with ethyl acetate (2*100 cm3). The organic phases are combined, dried over magnesium sulphate and concentrated under a vacuum. The residue is slowly removed in water, and the resultant suspension is filtered. The solid is dried under vacuum to obtain 1.58 g of 5-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine as a brown powder.

References

[1] Patent: WO2017/133667, 2017, A1. Location in patent: Page/Page column 117
[2] Patent: WO2008/79346, 2008, A1. Location in patent: Page/Page column 59
[3] Patent: WO2017/31325, 2017, A1. Location in patent: Paragraph 0524
[4] Patent: US2009/253679, 2009, A1. Location in patent: Page/Page column 42

1036027-52-7
1036027-54-9
Synthesis of 5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine from 5-(Trifluoromethyl)-3-((trimethylsilyl)ethynyl)-pyridin-2-amine

5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine Preparation Products And Raw materials

5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine Suppliers

Global( 87)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
KARMEL TECHNOLOGY (HK) CO.,LIMITED 		+8618795957998 karmelhk@126.com CHINA 2886 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58
Baoji Guokang Healthchem Co., Ltd. 		+86-0917-3909592 +86-13892490616 gksales1@gk-bio.com China 9050 58
CR Corporation Limited 		+8613062833949 fred.wen@crcorporation.cn China 8645 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Aceschem Inc. 		+1-817863-6948 +1-（817）863-6948 sales@aceschem.com United States 19632 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+86-18621343501; +undefined18621343501 product@acmec-e.com China 33324 58

View Lastest Price from 5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)- pictures 2021-07-13 1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)-
1036027-54-9
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)- pictures 2021-07-10 1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)-
1036027-54-9
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)- pictures 2019-12-20 1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)-
1036027-54-9
 $1.00 1KG 99% Career Henan Chemical Co

5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine Spectrum

1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)- 5-(TrifluoroMethyl)-7-azaindole 1H-Pyrrolo[2,3-b]pyridine, 5-(trifluoromethyl)- 5-(TrifluoroMethyl)-7-azaindole 5-TRIFLUOROMETHYL-1H-PYRROLO[2,3-B]PYRIDINE 1036027-54-9
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