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ChemicalBook >> CAS DataBase List >>methyl 3-hydroxy-5-methoxybenzoate

methyl 3-hydroxy-5-methoxybenzoate

CAS No.
19520-74-2
Chemical Name:
methyl 3-hydroxy-5-methoxybenzoate
Synonyms
Benzomold Impurity 6;methyl 3-hydroxy-5-methoxybenzoate;3-methoxy-5-hydroxy benzoic acid methyl ester;Benzoic acid, 3-hydroxy-5-methoxy-, methyl ester
CBNumber:
CB71908036
Molecular Formula:
C9H10O4
Molecular Weight:
182.17
MDL Number:
MFCD00601487
MOL File:
19520-74-2.mol
MSDS File:
SDS
Last updated:2026-05-28 02:51:00
Product description Number Pack Size Price
Methyl 3-hydroxy-5-methoxybenzoate UAA52074 2.5g $413
Methyl 3-hydroxy-5-methoxybenzoate 98% AS41302 250mg $179
Methyl 3-hydroxy-5-methoxybenzoate 98% AS41302 1g $378
Methyl 3-hydroxy-5-methoxybenzoate 307907 250.00mg $43
Methyl 3-hydroxy-5-methoxybenzoate 307907 1.00g $95

methyl 3-hydroxy-5-methoxybenzoate Properties

Melting point 94-95 °C
Boiling point 328.3±22.0 °C(Predicted)
Density 1.216±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 8.77±0.10(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338

methyl 3-hydroxy-5-methoxybenzoate price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth UAA52074 Methyl 3-hydroxy-5-methoxybenzoate 19520-74-2 2.5g $413 2026-06-05 Buy
Activate Scientific AS41302 Methyl 3-hydroxy-5-methoxybenzoate 98% 19520-74-2 250mg $179 2026-06-04 Buy
Activate Scientific AS41302 Methyl 3-hydroxy-5-methoxybenzoate 98% 19520-74-2 1g $378 2026-06-04 Buy
Matrix Scientific 307907 Methyl 3-hydroxy-5-methoxybenzoate 19520-74-2 250.00mg $43 2026-05-19 Buy
Matrix Scientific 307907 Methyl 3-hydroxy-5-methoxybenzoate 19520-74-2 1.00g $95 2026-05-19 Buy
Product number Packaging Price Buy
UAA52074 2.5g $413 Buy
AS41302 250mg $179 Buy
AS41302 1g $378 Buy
307907 250.00mg $43 Buy
307907 1.00g $95 Buy

methyl 3-hydroxy-5-methoxybenzoate Chemical Properties,Uses,Production

Synthesis

Methyl 3,5-dihydroxybenzoate

2150-44-9

Iodomethane

74-88-4

methyl 3-hydroxy-5-methoxybenzoate

19520-74-2

The reaction was carried out with methyl 3,5-dihydroxybenzoate (104 g) and iodomethane (36 mL) in the presence of potassium carbonate (79 g) and dimethylformamide (1200 mL) with stirring at room temperature for 16 hours. After completion of the reaction, the reaction mixture was partitioned between water (2.5 L) and petroleum ether (boiling point 60-80 °C, 600 mL). The aqueous layer was washed with petroleum ether (boiling point 60-80 °C, 600 mL) and then extracted with toluene (2 x 1 L). The toluene extracts were combined, washed sequentially with water (4×800 mL), dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to give methyl 3-hydroxy-5-methoxybenzoate as an oil (33 g, 30% yield).

References

[1] Synlett, 2016, vol. 27, # 10, p. 1587 - 1591
[2] European Journal of Medicinal Chemistry, 2013, vol. 63, p. 415 - 422
[3] Journal of the American Chemical Society, 2005, vol. 127, # 6, p. 1737 - 1743
[4] Journal of Organic Chemistry, 2013, vol. 78, # 11, p. 5587 - 5603
[5] Synlett, 2006, # 9, p. 1363 - 1366

methyl 3-hydroxy-5-methoxybenzoate Preparation Products And Raw materials

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methyl 3-hydroxy-5-methoxybenzoate Benzoic acid, 3-hydroxy-5-methoxy-, methyl ester 3-methoxy-5-hydroxy benzoic acid methyl ester Benzomold Impurity 6 19520-74-2
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