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ChemicalBook >> CAS DataBase List >>BOC-SER(ME)-OH

BOC-SER(ME)-OH

CAS No.
51293-47-1
Chemical Name:
BOC-SER(ME)-OH
Synonyms
BOC-O-METHYL-L-SERINE;BOC-SER(ME)-OH;BOC-L-Ser(Me)-OH;Boc-O-Methyl-L-Se;BOC-O-METHYL-L-SER;BOC-SER(ME)-OH DCHA;BOC-SERINE(ME)-OH DCHA;N-Boc-O-methyl-L-serine;BOC-L-SERINE(METHYL ETHER);BOC-O-METHYL-L-SERINE DCHA
CBNumber:
CB7218147
Molecular Formula:
C9H17NO5
Molecular Weight:
219.24
MDL Number:
MFCD00153314
MOL File:
51293-47-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:46:45
Product description Number Pack Size Price
Boc-Ser(Me)-OH 263738 100g $1692
Boc-Ser(Me)-OH 263738 250g $3186
Boc-Ser(Me)-OH 263738 500g $4962
Boc-Ser(Me)-OH 263738 1kg $7568
Boc-Ser(Me)-OH 263738 2kg $13499
More product size

BOC-SER(ME)-OH Properties

Boiling point 355.8±37.0 °C(Predicted)
Density 1.148±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
pka 3.52±0.10(Predicted)
form solid
color Yellow-brown
InChI InChI=1S/C9H17NO5/c1-9(2,3)15-8(13)10-6(5-14-4)7(11)12/h6H,5H2,1-4H3,(H,10,13)(H,11,12)/t6-/m0/s1
InChIKey RFGMSGRWQUMJIR-LURJTMIESA-N
SMILES C(O)(=O)[C@H](COC)NC(OC(C)(C)C)=O
CAS DataBase Reference 51293-47-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HazardClass  IRRITANT
HS Code  2924297099
NFPA 704
1
0 0

BOC-SER(ME)-OH price More Price(89)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 263738 Boc-Ser(Me)-OH 51293-47-1 100g $1692 2026-06-03 Buy
Usbiological 263738 Boc-Ser(Me)-OH 51293-47-1 250g $3186 2026-06-03 Buy
Usbiological 263738 Boc-Ser(Me)-OH 51293-47-1 500g $4962 2026-06-03 Buy
Usbiological 263738 Boc-Ser(Me)-OH 51293-47-1 1kg $7568 2026-06-03 Buy
Usbiological 263738 Boc-Ser(Me)-OH 51293-47-1 2kg $13499 2026-06-03 Buy
Product number Packaging Price Buy
263738 100g $1692 Buy
263738 250g $3186 Buy
263738 500g $4962 Buy
263738 1kg $7568 Buy
263738 2kg $13499 Buy

BOC-SER(ME)-OH Chemical Properties,Uses,Production

Chemical Properties

White to off-white crystals

Uses

BOC-SER(ME)-OH, also known as Boc-Ser-OMe or N-tert-butyloxycarbonyl-L-serine methyl ester, is an amino acid derivative commonly used in peptide synthesis.

Synthesis

O-methylserine

4219-94-7

Di-tert-butyl dicarbonate

24424-99-5

BOC-SER(ME)-OH

51293-47-1

General procedure for the synthesis of N-Boc-O-methyl-L-serine from O-methyl DL-serine and di-tert-butyl dicarbonate: 35 mL of aqueous 1 N sodium hydroxide solution and 35 mL of tetrahydrofuran (THF) were added to 2.0 g (17 mmol) of O-methyl DL-serine. With stirring at 0 °C, a solution of di-tert-butyl dicarbonate (4.03 g, 18.5 mmol) in THF (15 mL) was added slowly. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the reaction mixture was concentrated by evaporation under reduced pressure. The aqueous phase was acidified to pH 4-5 with 10% aqueous citric acid and then extracted with ethyl acetate. The organic phase was washed with saturated brine, dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure to give 3.6 g of N-Boc-O-methyl-L-serine (98% yield). Mass spectrum (ESI) m/z: 220.1 (M + H)+.

References

[1] Chemistry - A European Journal, 2011, vol. 17, # 15, p. 4183 - 4194
[2] Patent: WO2016/11088, 2016, A2. Location in patent: Paragraph 00238; 00239

75-18-3
3262-72-4
51293-47-1
Synthesis of BOC-SER(ME)-OH from Dimethyl sulfide and BOC-L-Serine
Global( 226)Suppliers
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View Lastest Price from BOC-SER(ME)-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-ser(me)-OH pictures 2020-01-06 Boc-ser(me)-OH
51293-47-1
$1.00 1g 98% 100KG Sichuan Jiaying Lai Technology Co.,LTD
BOC-SER(ME)-OH pictures 2019-07-06 BOC-SER(ME)-OH
51293-47-1
$100.00 1KG 99% Career Henan Chemical Co
  • Boc-ser(me)-OH pictures
  • Boc-ser(me)-OH
    51293-47-1
  • $1.00
  • 98%
  • Sichuan Jiaying Lai Technology Co.,LTD

BOC-SER(ME)-OH Spectrum

BOC-L-Ser(Me)-OH (2S)-2-(tert-Butoxycarbonylamino)-3-methoxy-propanoic acid (S)-N-BOC-2-AMINO-3-METHOXY-PROPIONIC ACID N-ALPHA-T-BUTOXYCARBONYL-O-METHYL-L-SERINE N-ALPHA-T-BUTOXYCARBONYL-O-METHYL-L-SERINE DICYCLOHEXYLAMMONIUM SALT N-ALPHA-T-BOC-O-METHYL-L-SERINE BOC-(S)-2-AMINO-3-METHOXYLPROPANOIC ACID BOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID BOC-SER(ME)-OH BOC-SER(ME)-OH DCHA BOC-SERINE(ME)-OH DCHA Boc-O-methyl-L-serine dicyclohexylammonium salt≥ 98.5% (HPLC) BOC-L-SERINE(METHYL ETHER) BOC-O-METHYL-L-SER BOC-O-METHYL-L-SERINE DCHA BOC-O-METHYL-L-SERINE DICYCLOHEXYLAMMONIUM SALT Boc-O-methyl-L-Serinedicyclohexylamine salt Boc-O-Methyl-L-Se N-tert-Butoxycarbonyl-O-methyl-L-serine (S)-2-(tert-butoxycarbonylamino)-3-methoxypropanoicacid L-Serine, N-[(1,1-diMethylethoxy)carbonyl]-O-Methyl- Boc-Ser(Me)-OH·DCHA Boc-O-Methyl-L-SerinedicyclohexylaMine salt N-Boc-O-Methyl-L-serine, 97% N-α-(t-Butoxycarbonyl)-O-methyl-L-serine N-tert-butoxycarbonyl-(S)-O-methyl-serin (S)-N-Boc-2-Amino-3-Methoxy-PropionicAci N-Boc-O-methyl-L-serine,97% (2S)-2-Amino-3-methoxypropanoic acid, N-BOC protected N-[(1,1-Dimethylethoxy)carbonyl]-O-methyl-L-serine (2S)-3-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid N-Boc-O-methyl-L-serine BOC-O-METHYL-L-SERINE 51293-47-1 C9H17NO5C12H23N unnatural amino acids Boc-Amino acid series Serine [Ser, S] Boc-Amino Acids and Derivative API
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