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4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE

CAS No.
1072895-86-3
Chemical Name:
4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE
Synonyms
4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE;1H-Pyrazolo[3,4-d]pyrimidine, 4,6-dichloro-1,3-dimethyl-
CBNumber:
CB72466575
Molecular Formula:
C7H6Cl2N4
Molecular Weight:
217.06
MDL Number:
MFCD11869749
MOL File:
1072895-86-3.mol
MSDS File:
SDS
Last updated:2026-05-28 02:48:16
Product description Number Pack Size Price
4,6-Dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine ≥95% OR30659 250mg $185
4,6-Dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine ≥95% OR30659 1g $436
4,6-dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine 187837 5.00g $2428
4,6-Dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine 95% AA008TZX 100mg $163
4,6-Dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine 95% AA008TZX 250mg $185

4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE Properties

Density 1.66±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 0.09±0.30(Predicted)
form solid
color White

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
HS Code  2933998090

4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR30659 4,6-Dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine ≥95% 1072895-86-3 250mg $185 2026-06-04 Buy
Apolloscientific OR30659 4,6-Dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine ≥95% 1072895-86-3 1g $436 2026-06-04 Buy
Matrix Scientific 187837 4,6-dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine 1072895-86-3 5.00g $2428 2026-05-18 Buy
aablocks AA008TZX 4,6-Dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine 95% 1072895-86-3 100mg $163 2026-05-28 Buy
aablocks AA008TZX 4,6-Dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine 95% 1072895-86-3 250mg $185 2026-05-28 Buy
Product number Packaging Price Buy
OR30659 250mg $185 Buy
OR30659 1g $436 Buy
187837 5.00g $2428 Buy
AA008TZX 100mg $163 Buy
AA008TZX 250mg $185 Buy

4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE Chemical Properties,Uses,Production

Synthesis

1,3-Dimethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-d]-pyrimidine-4,6-dione

1072895-79-4

4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE

1072895-86-3

1,3-Dimethyl-1,7-dihydro-pyrazolo[3,4-d]pyrimidine-4,6-dione (1 g, 5.56 mmol) was used as starting material and mixed with phosphorus pentachloride (3.47 g, 3 equiv.) in phosphorus trichloride (20 mL). The reaction mixture was heated to reflux for 18 hours. Upon completion of the reaction, the excess phosphorous trichloride was removed by distillation under reduced pressure. The residue was carefully poured onto ice and extracted with dichloromethane (3 x 20 mL). The organic phases were combined and purified by column chromatography to give 4,6-dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine (680 mg, 63% yield) as a final product as a beige solid.

References

[1] Patent: WO2009/97446, 2009, A1. Location in patent: Page/Page column 65; 66
[2] Tetrahedron Letters, 2008, vol. 49, # 42, p. 6081 - 6083

4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE Preparation Products And Raw materials

4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE Suppliers

Global( 28)Suppliers
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Alchem Pharmtech,Inc.
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Blocksynth Pharmaceutical Technology Co.,Ltd
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Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42056 58
Amadis Chemical Company Limited
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J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10186 62
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16101 64
NovoChemy Ltd. -- sales@novochemy.com Germany 6328 58
EnliPharma Technology Co., Ltd 0551-66399836 18955197623 sales@enlipharma.com China 1876 55
Bellen Chemistry Co., Ltd. 010-60400365-8001 15910885229 service@bellenchem.com China 4514 60
4,6-DICHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE 1H-Pyrazolo[3,4-d]pyrimidine, 4,6-dichloro-1,3-dimethyl- 1072895-86-3 Building Blocks Pyrazolo[x,x-y]pyridine
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