1H-INDAZOLE, 5-IODO-1-METHYL-
- CAS No.
- 1072433-59-0
- Chemical Name:
- 1H-INDAZOLE, 5-IODO-1-METHYL-
- Synonyms
- 5-Iodo-1-methyl-1H-indazole;5-iodo-1-methylindazole;1H-INDAZOLE, 5-IODO-1-METHYL-
- CBNumber:
- CB72467512
- Molecular Formula:
- C8H7IN2
- Molecular Weight:
- 258.06
- MDL Number:
- MFCD11977535
- MOL File:
- 1072433-59-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Iodo-1-methyl-1H-indazole | XSB43359 | 5g | $413 |
| 5-Iodo-1-methyl-1H-indazole 98% | AS42649 | 1g | $75 |
| 5-Iodo-1-methyl-1H-indazole 98% | AS42649 | 5g | $339 |
| 5-Iodo-1-methyl-1H-indazole 98% | AS42649 | 25g | $1047 |
| 5-Iodo-1-methyl-1H-indazole | 218938 | 250.00mg | $51 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
1H-INDAZOLE, 5-IODO-1-METHYL- price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | XSB43359 | 5-Iodo-1-methyl-1H-indazole | 1072433-59-0 | 5g | $413 | 2026-06-05 | Buy |
| Activate Scientific | AS42649 | 5-Iodo-1-methyl-1H-indazole 98% | 1072433-59-0 | 1g | $75 | 2026-06-04 | Buy |
| Activate Scientific | AS42649 | 5-Iodo-1-methyl-1H-indazole 98% | 1072433-59-0 | 5g | $339 | 2026-06-04 | Buy |
| Activate Scientific | AS42649 | 5-Iodo-1-methyl-1H-indazole 98% | 1072433-59-0 | 25g | $1047 | 2026-06-04 | Buy |
| Matrix Scientific | 218938 | 5-Iodo-1-methyl-1H-indazole | 1072433-59-0 | 250.00mg | $51 | 2026-05-18 | Buy |
1H-INDAZOLE, 5-IODO-1-METHYL- Chemical Properties,Uses,Production
Synthesis
50593-24-3
1072433-59-0
General procedure for the synthesis of 5-iodo-1-methyl-1H-indazole from 1-methyl-1H-indazol-5-amine: 1. add 1-methyl-1H-indazol-5-amine (500 mg, 3.40 mmol) to a mixture of concentrated sulfuric acid (1.3 mL) and water (5.5 mL) at 0 °C. 2. a solution of sodium nitrite (258 mg, 3.74 mmol) in water (0.5 mL) was added dropwise to the above mixture. 3. The reaction mixture was stirred at 0 °C for 10 min. 4. The stirred mixture was added dropwise to a solution of sodium iodide (1.5 g) in water (4.5 mL) cooled to 0 °C. 5. After addition, the reaction mixture was heated to 90°C and held for 20 minutes. 6. After completion of the reaction, the resulting mixture was alkalized with dilute sodium hydroxide solution and extracted with ethyl acetate. 7. The organic phase was washed with brine, dried over magnesium sulfate and then concentrated in vacuum. 8. The residue was purified by fast column chromatography on silica gel using a petroleum ether solution of 20% EtOAc as eluent to afford the title compound 5-iodo-1-methyl-1H-indazole (475 mg, 54% yield). 1H NMR (DMSO D6, 400 MHz) δ 4.03 (3H, s), 7.52 (1H, d), 7.63 (1H, dd), 7.99 (1H, s), 8.17 (1H, s).
References
[1] Patent: WO2008/128009, 2008, A2. Location in patent: Page/Page column 47-48
1H-INDAZOLE, 5-IODO-1-METHYL- Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1H-INDAZOLE, 5-IODO-1-METHYL- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579 | sales@zeroschem.com | China | 1391 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16303 | 64 |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
