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ChemicalBook >> CAS DataBase List >>7-Chloro-[1,8]naphthyridin-2-ol

7-Chloro-[1,8]naphthyridin-2-ol

CAS No.
15944-34-0
Chemical Name:
7-Chloro-[1,8]naphthyridin-2-ol
Synonyms
7-Chloro-1H-[1,8]naphthyridin-2-one;7-Chloro-[1,8]naphthyridin-2-ol;1,8-Naphthyridin-2(1H)-one, 7-chloro-
CBNumber:
CB72491645
Molecular Formula:
C8H5ClN2O
Molecular Weight:
180.59
MDL Number:
MFCD17215762
MOL File:
15944-34-0.mol
MSDS File:
SDS
Last updated:2026-05-28 03:14:38
Product description Number Pack Size Price
7-Chloro-1,8-naphthyridin-2-ol QAA94434 100mg $342
7-Chloro-1,8-naphthyridin-2-ol QAA94434 1g $1073.8
7-Chloro-1,8-naphthyridin-2-ol 297497 100.00mg $139
7-Chloro-1,8-naphthyridin-2-ol 297497 250.00mg $269
7-Chloro-1,8-naphthyridin-2-ol 297497 1.00g $506

7-Chloro-[1,8]naphthyridin-2-ol Properties

Melting point 255-257℃
Boiling point 379.4±44.0 °C(Predicted)
Density 1.50
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 1.74±0.40(Predicted)
Appearance Brown to reddish brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H335-H319
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

7-Chloro-[1,8]naphthyridin-2-ol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth QAA94434 7-Chloro-1,8-naphthyridin-2-ol 15944-34-0 100mg $342 2026-06-04 Buy
Biosynth QAA94434 7-Chloro-1,8-naphthyridin-2-ol 15944-34-0 1g $1073.8 2026-06-04 Buy
Matrix Scientific 297497 7-Chloro-1,8-naphthyridin-2-ol 15944-34-0 100.00mg $139 2026-05-19 Buy
Matrix Scientific 297497 7-Chloro-1,8-naphthyridin-2-ol 15944-34-0 250.00mg $269 2026-05-19 Buy
Matrix Scientific 297497 7-Chloro-1,8-naphthyridin-2-ol 15944-34-0 1.00g $506 2026-05-19 Buy
Product number Packaging Price Buy
QAA94434 100mg $342 Buy
QAA94434 1g $1073.8 Buy
297497 100.00mg $139 Buy
297497 250.00mg $269 Buy
297497 1.00g $506 Buy

7-Chloro-[1,8]naphthyridin-2-ol Chemical Properties,Uses,Production

Synthesis

3-Pyridinepropanoic acid, 6-chloro-2-[(2,2-dimethyl-1-oxopropyl)amino]-β-hydroxy-, 1,1-dimethylethyl ester

127446-41-7

7-Chloro-[1,8]naphthyridin-2-ol

15944-34-0

Tert-butyl 3-[6-chloro-2-(2,2-dimethylpropanamido)pyridin-3-yl]-3-hydroxypropanoate (4 g, 11 mmol) was used as a raw material, which was dissolved in a mixed solution of 1 M HCl/dioxane (1:1, 50 mL) and reacted overnight. After completion of the reaction, ice water was added to the mixture and the precipitated solid was collected by filtration and dried to afford 7-chloro-1,8-diazanaphthalen-2-ol (1.7 g, 9.4 mmol, 86% yield). The obtained product could be used in the subsequent reaction without further purification.LC-MS analysis showed the (M-H)-peak was 181.1.

References

[1] Journal of Organic Chemistry, 1990, vol. 55, # 15, p. 4744 - 4750
[2] Patent: WO2017/211759, 2017, A1. Location in patent: Page/Page column 94

7-Chloro-[1,8]naphthyridin-2-ol Suppliers

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16676 50

7-Chloro-[1,8]naphthyridin-2-ol Spectrum

7-Chloro-[1,8]naphthyridin-2-ol 1,8-Naphthyridin-2(1H)-one, 7-chloro- 7-Chloro-1H-[1,8]naphthyridin-2-one 15944-34-0
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