ChemicalBook >> CAS DataBase List >>15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester
15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester
- CAS No.
- 459426-22-3
- Chemical Name:
- 15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester
- Synonyms
- Biotin-PEG4-NHS;Biotin-PEG4-NHS ester;NHS-dPEG ®Biotin-PEG4-SPA;NHS-PEG4-Biotin;NHS-dPEG4-Biotin;Biotin-PEG4-PA-NHS;NHS-dPEG(R)4-biotin;(+)-Biotin-PEG4-NHS Ester;Biotin-PEG4-NHS-propionate
- CBNumber:
- CB72546806
- Molecular Formula:
- C25H40N4O10S
- Molecular Weight:
- 588.67
- MDL Number:
- MFCD08458915
- MOL File:
- 459426-22-3.mol
- MSDS File:
- SDS
Last updated:2026-01-13 11:23:57
| Product description | Number | Pack Size | Price |
| NHS-dPEG?4-biotin | QBD10200 | 50MG | $179 |
| NHS-dPEG?4-biotin | QBD10200 | 1000 mg | $1160 |
| Biotin-PEG4-NHS ester ≥90% | 29114 | 25mg | $72 |
| Biotin-PEG4-NHS ester ≥90% | 29114 | 50mg | $134 |
| Biotin-PEG4-NHS ester ≥90% | 29114 | 100mg | $252 |
| More product size | |||
| Density | 1.33±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | -20°C |
| solubility | Soluble in DMSO, DMF, DCM |
| pka | 13.90±0.40(Predicted) |
| form | solid or viscous liquid |
| color | White to light yellow |
| Appearance | white to off-beige powder |
| InChIKey | DTLVBHCSSNJCMJ-JXQFQVJHSA-N |
| SMILES | C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@H]1[C@@]2([H])NC(=O)N[C@@]2([H])CS1 |
| UNSPSC Code | 12161502 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Precautionary statements | P271-P261-P280 |
|---|---|
| HS Code | 2942000090 |
| Storage Class | 11 - Combustible Solids |
15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | QBD10200 | NHS-dPEG?4-biotin | 459426-22-3 | 50MG | $179 | 2026-04-30 | Buy |
| Sigma-Aldrich | QBD10200 | NHS-dPEG?4-biotin | 459426-22-3 | 1000 mg | $1160 | 2026-04-30 | Buy |
| Cayman Chemical | 29114 | Biotin-PEG4-NHS ester ≥90% | 459426-22-3 | 25mg | $72 | 2026-04-30 | Buy |
| Cayman Chemical | 29114 | Biotin-PEG4-NHS ester ≥90% | 459426-22-3 | 50mg | $134 | 2026-04-30 | Buy |
| Cayman Chemical | 29114 | Biotin-PEG4-NHS ester ≥90% | 459426-22-3 | 100mg | $252 | 2026-04-30 | Buy |
15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester Chemical Properties,Uses,Production
Description
Biotin-PEG4-NHS is an amine reactive reagent that contains biotin linked via a four-unit PEG spacer to N-hydroxysuccinimide (NHS), which facilitates the coupling of biotin to primary amines. Biotin-PEG4-NHS has been used in the biotinylation of proteins and antibodies.
Uses
Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
reaction suitability
reagent type: cross-linking reagent
reaction type: Biotinylations
reactivity: amine reactive
reagent type: linker
IC 50
PEGs
References
[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329
15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 133)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 | contact@trustwe.com | China | 5742 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| XIAMEN SINOPEG BIOTECH CO., LTD. | +86-0592-7761068 15616186207 | changaiwei@sinopeg.com | China | 1133 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3147 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19905 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +86-18327326525 | masar@topule.com | China | 8433 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
View Lastest Price from 15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-20 | Biotin-PEG4-NHS ester
459426-22-3
|
10g | TargetMol Chemicals Inc. | ||||
 |
2025-06-07 | Biotin-PEG4-NHS ester
459426-22-3
|
1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
-
- Biotin-PEG4-NHS ester
459426-22-3
- $0.00
- TargetMol Chemicals Inc.
-
- Biotin-PEG4-NHS ester
459426-22-3
- $0.00
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
459426-22-3(15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester)Related Search:
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459426-22-3
C25H40N4O10S
SiChem
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