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ChemicalBook >> CAS DataBase List >>3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

CAS No.
1479-24-9
Chemical Name:
3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
Synonyms
ETHYL 3-(2-FLUOROPHENYL)-3-OXOPROPANOATE;RMA-126;NSC 166423;ETHYL 2-FLUOROBENZOYLACETATE;Ethyl(2-Fluorobenzoyl)acetate>2-Fluorobenzoylacetic acid ethyl ester;2-[(2-fluorophenyl)-oxomethyl]butanoate;Ethyl 3-oxo-3-(2-fluorophenyl)propionate;Ethyl 3-(2-fluorophenyl)-3-oxo-propionate;Ethyl (2-fluorobenzoyl)acetate technical grade
CBNumber:
CB7331507
Molecular Formula:
C11H11FO3
Molecular Weight:
210.2
MDL Number:
MFCD00000321
MOL File:
1479-24-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-20 15:45:00
Product description Number Pack Size Price
Ethyl (2-fluorobenzoyl)acetate technical grade 225134 10g $1130
Ethyl (2-fluorobenzoyl)acetate technical grade 225134 1g $176
Ethyl (2-Fluorobenzoyl)acetate >98.0%(GC)(T) E1097 5g $80
Ethyl (2-Fluorobenzoyl)acetate >98.0%(GC)(T) E1097 25g $283
Ethyl (2-fluorobenzoyl)acetate ≥98%(GC) 45316 5G $109.3
More product size

3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Properties

Boiling point 124-125℃ (1.5 Torr)
Density 1.164 g/mL at 25 °C(lit.)
refractive index n20/D 1.516(lit.)
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form Liquid
pka 10.03±0.46(Predicted)
color Colorless to Light orange to Yellow
InChI 1S/C11H11FO3/c1-2-15-11(14)7-10(13)8-5-3-4-6-9(8)12/h3-6H,2,7H2,1H3
InChIKey YMUNUVJSNWUWDA-UHFFFAOYSA-N
SMILES CCOC(=O)CC(=O)c1ccccc1F
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

PPE Eyeshields, Gloves
WGK Germany  3
HS Code  2918.30.9000
Storage Class 10 - Combustible liquids
NFPA 704
1
0 0

3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 225134 Ethyl (2-fluorobenzoyl)acetate technical grade 1479-24-9 10g $1130 2026-04-30 Buy
Sigma-Aldrich 225134 Ethyl (2-fluorobenzoyl)acetate technical grade 1479-24-9 1g $176 2023-06-20 Buy
TCI Chemical E1097 Ethyl (2-Fluorobenzoyl)acetate >98.0%(GC)(T) 1479-24-9 5g $80 2026-04-30 Buy
TCI Chemical E1097 Ethyl (2-Fluorobenzoyl)acetate >98.0%(GC)(T) 1479-24-9 25g $283 2026-04-30 Buy
Chem-Impex 45316 Ethyl (2-fluorobenzoyl)acetate ≥98%(GC) 1479-24-9 5G $109.3 2026-05-19 Buy
Product number Packaging Price Buy
225134 10g $1130 Buy
225134 1g $176 Buy
E1097 5g $80 Buy
E1097 25g $283 Buy
45316 5G $109.3 Buy

3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Chemical Properties,Uses,Production

Uses

Ethyl (2-fluorobenzoyl)acetate may be used in chemical synthesis.

Synthesis

Ethanol

64-17-5

1,3-Dioxane-4,6-dione, 5-(2-fluorobenzoyl)-2,2-dimethyl-

223679-79-6

3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

1479-24-9

GENERAL METHOD: An appropriate amount of diketone (9a or 9b) (0.3 mol) was mixed with ethanol (500 mL), heated to 80 °C and refluxed for 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the solvent was removed by distillation under reduced pressure to give the target product ester (10a or 10b) in the form of a red oil. 7.10.1 Preparation of ethyl 3-(2-fluorophenyl)-3-oxopropanoate (10a): the product obtained was a red oily material in 85% yield; mass spectrum (ESI) m/z: 233.1 [M + Na] , 443.1 [2M + Na]

References

[1] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 11, p. 2843 - 2855
[2] Archiv der Pharmazie, 2013, vol. 346, # 7, p. 521 - 533
[3] Patent: EP2799437, 2014, A1. Location in patent: Paragraph 0057
[4] Patent: US2014/364431, 2014, A1. Location in patent: Paragraph 0188
[5] Patent: WO2017/37672, 2017, A1. Location in patent: Page/Page column 48

3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER Preparation Products And Raw materials

Global( 107)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
Alchem Pharmtech,Inc.
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CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
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Blocksynth Pharmaceutical Technology Co.,Ltd
0086-19817745290; +8619817745290 bd@blocksynth.com China 5973 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52704 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615531151365 mina@chuanghaibio.com China 18126 58
PT CHEM GROUP LIMITED
+86-85511178; peter68@ptchemgroup.com China 35425 58

View Lastest Price from 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER pictures 2019-12-20 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
1479-24-9
$1.00 1ASSAYS 99% Career Henan Chemical Co
Ethyl 3-oxo-3-(2-fluorophenyl)propionate NSC 166423 Ethyl (2-fluorobenzoyl)acetate technical grade Ethyl 3-(2-fluorophenyl)-3-oxo-propionate 2-Fluorobenzoylacetic acid ethyl ester 3-Oxo-3-(2-fluorophenyl)propionic acid ethyl ester β-Oxo-2-fluorobenzenepropanoic acid ethyl ester Benzenepropanoic acid, 2-fluoro-b-oxo-, ethyl ester ETHYL 2-FLUOROBENZOYLACETATE 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER 2-[(2-fluorophenyl)-oxomethyl]butanoate Ethyl(2-Fluorobenzoyl)acetate> Benzenepropanoic acid, 2-fluoro-β-oxo-, ethyl ester RMA-126 Benzenepropanoic acid, 2-fluoro-β-oxo-, ethyl ester ETHYL 3-(2-FLUOROPHENYL)-3-OXOPROPANOATE 1479-24-9 Building Blocks Carbonyl Compounds C10 to C11 Organic Building Blocks Esters Aryl Fluorinated Building Blocks Building Blocks C10 to C11 C8-C12 Carbonyl Compounds Chemical Synthesis Fluorinated Building Blocks Organic Building Blocks Organic Fluorinated Building Blocks Other Fluorinated Organic Building Blocks C10 to C11 Carbonyl Compounds Esters
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