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ChemicalBook >> CAS DataBase List >>2-PHENYL-5-OXAZOLONE

2-PHENYL-5-OXAZOLONE

CAS No.
1199-01-5
Chemical Name:
2-PHENYL-5-OXAZOLONE
Synonyms
Phenyloxazolone;2-phenyloxazolone;2-PHENYL-5-OXAZOLONE;2-phenyl-5(4h)-oxazolon;2-Phenyl-5(4H)-oxazolone;2-PHENYL-4H-OXAZOL-5-ONE;2-PHENYL-2-OXAZOLIN-5-ONE;2-Phenyl-2-oxazoline-5-one;2-phenyl-4H-1,3-oxazol-5-one
CBNumber:
CB7469864
Molecular Formula:
C9H7NO2
Molecular Weight:
161.16
MDL Number:
MFCD00014517
MOL File:
1199-01-5.mol
MSDS File:
SDS
Last updated:2026-05-28 02:50:17
Product description Number Pack Size Price
2-PHENYL-2-OXAZOLIN-5-ONE AldrichCPR S554243 1 unit $152
2-PHENYL-4H-OXAZOL-5-ONE AldrichCPR S301604 1 unit $32.7
2-PHENYL-2-OXAZOLIN-5-ONE Aldrich S554243 250mg $139
2-PHENYL-4H-OXAZOL-5-ONE Aldrich S301604 25mg $29.8
2-PHENYL-4H-OXAZOL-5-ONE 95% 65136 0.25G $39

2-PHENYL-5-OXAZOLONE Properties

Melting point 89-92°C
Boiling point 248.1±23.0 °C(Predicted)
Density 1.25±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Soluble in most common organic solvents.
pka 2.56±0.20(Predicted)
Appearance Off-white to light yellow Solid
Sensitive Air Sensitive
BRN 128465
EPA Substance Registry System 5(4H)-Oxazolone, 2-phenyl- (1199-01-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H312-H315-H318-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Safety Statements  22-24/25
TSCA  TSCA listed
NFPA 704
1
0 0

2-PHENYL-5-OXAZOLONE price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S554243 2-PHENYL-2-OXAZOLIN-5-ONE AldrichCPR 1199-01-5 1 unit $152 2026-04-30 Buy
Sigma-Aldrich S301604 2-PHENYL-4H-OXAZOL-5-ONE AldrichCPR 1199-01-5 1 unit $32.7 2026-04-30 Buy
Sigma-Aldrich S554243 2-PHENYL-2-OXAZOLIN-5-ONE Aldrich 1199-01-5 250mg $139 2024-03-01 Buy
Sigma-Aldrich S301604 2-PHENYL-4H-OXAZOL-5-ONE Aldrich 1199-01-5 25mg $29.8 2024-03-01 Buy
AstaTech 65136 2-PHENYL-4H-OXAZOL-5-ONE 95% 1199-01-5 0.25G $39 2026-04-30 Buy
Product number Packaging Price Buy
S554243 1 unit $152 Buy
S301604 1 unit $32.7 Buy
S554243 250mg $139 Buy
S301604 25mg $29.8 Buy
65136 0.25G $39 Buy

2-PHENYL-5-OXAZOLONE Chemical Properties,Uses,Production

Uses

2-Phenyl-5-oxazolone is a reagent used as a masked glycine equivalent and for the formation of heterocyclic structures, it can be used to produce 4-benzylidene-2-phenyl-4H-oxazol-5-one.

Definition

ChEBI: A 1,3-oxazole having a phenyl substituent at the 2-position and an oxo group at the 5-position. Note that phenyloxazolone is commonly used as a synonym for 4-(ethoxymethylene)-2-phenyloxazol-5-one (PhOx).

Synthesis

Hippuric acid

495-69-2

2-PHENYL-5-OXAZOLONE

1199-01-5

The general procedure for the synthesis of 2-phenyl-5-azolone from equine uric acid was as follows: equine uric acid (5.0 g, 27.9 mmol) and EDCI-HCl (7.0 g, 36.3 mmol) were dissolved in dichloromethane (50 mL) and stirred for 45 min at room temperature under nitrogen protection. Upon completion of the reaction, the reaction was quenched with water. The organic layer was separated and washed twice with water and once with brine sequentially, then dried with anhydrous magnesium sulfate. After filtration, the filtrate was concentrated in vacuum to afford 2-phenyl-5-azolone as an off-white solid (4.1 g, 91% yield), which could be used in the next reaction without further purification. The nuclear magnetic resonance hydrogen spectrum (1H NMR, 600 MHz, CDCl3) data of the product were as follows: δ 7.96 (dd, J = 5.2, 3.3 Hz, 2H), 7.55 (m, 1H), 7.46 (m, 2H), 4.38 (s, 2H). Nuclear magnetic resonance carbon spectroscopy (13C NMR, 151 MHz, CDCl3) data were as follows: δ 176.00, 163.54, 132.87, 129.09, 128.88, 128.66, 127.86, 125.94, 77.37, 77.16, 76.95, 55.04.

References

[1] Organic Letters, 2016, vol. 18, # 4, p. 696 - 699
[2] Patent: WO2017/147646, 2017, A1. Location in patent: Page/Page column 42; 43
[3] Synthesis, 1982, # 3, p. 191 - 193
[4] Synthetic Communications, 1980, vol. 10, # 10, p. 761 - 766
[5] Journal of Heterocyclic Chemistry, 1994, vol. 31, # 5, p. 1145 - 1150

2-PHENYL-5-OXAZOLONE Suppliers

Global( 101)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Nanjing jinheyou Trading Co., Ltd. 		15705188088 admin@jheyou.com CHINA 1268 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Hangzhou Huarong Pharm Co., Ltd. 		571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3148 58
SUZHOU SENFEIDA CHEMICAL CO.,LTD 		+86-0512-83500002 +8618662433356 3899766280@qq.com China 26362 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 43333 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Qingdao Dexin Chemical Co., Ltd 		+86-15553333686 15553333686@qq.com China 3113 58
Suzhou ARTK Medchem Co., Ltd. 		+8618118463618 sales1@artkmedchem.com China 39021 58
Shandong Liteng Biotechnology Co. , Ltd. 		+86-18663721413 +86-15552573001 rosy@litengpharm.com China 3280 58

View Lastest Price from 2-PHENYL-5-OXAZOLONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-PHENYL-5-OXAZOLONE pictures 2026-06-30 2-PHENYL-5-OXAZOLONE
1199-01-5
 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2-PHENYL-5-OXAZOLONE pictures 2019-12-31 2-PHENYL-5-OXAZOLONE
1199-01-5
 $6.60 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co
2-PHENYL-5-OXAZOLONE pictures 2019-11-08 2-PHENYL-5-OXAZOLONE
1199-01-5
 1g 98%min 20kg/month Nanjing jinheyou Trading Co., Ltd.

2-PHENYL-5-OXAZOLONE Spectrum

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