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Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody

CAS No.
Chemical Name:
Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody
Synonyms
Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody
CBNumber:
CB75672386
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody Chemical Properties,Uses,Production

Source

Rabbit

Reactivity

Human;Mouse;Rat;Monkey

Background

Acetyl-CoA carboxylase catalyzes the carboxylation of acetyl-CoA to malonyl-CoA. It is the key enzyme in the biosynthesis and oxidation of fatty acids. In rodents, the 265 kDa ACC1 form is primarily expressed in lipogenic tissues, while 280 kDa ACC2 is the main isoform in oxidative tissues. However, in humans, ACC2 is the predominant isoform in both lipogenic and oxidative tissues. Phosphorylation by AMPK at Ser79 or by PKA at Ser1200 inhibits the enzymatic activity of ACC. ACC is a potential target of anti-obesity drugs.

References

[1] Castle, J.C. et al. (2009) PLoS One 4, e4369.
[2] Kreuz, S. et al. (2009) Diabetes Metab Res Rev 25, 577-86.
[3] Ha, J. et al. (1994) J Biol Chem 269, 22162-8.
[4] Abu-Elheiga, L. et al. (2001) Science 291, 2613-6.
[5] Levert, K.L. et al. (2002) J Biol Chem 277, 16347-50.
[6] Hadad, S.M. et al. (2009) BMC Cancer 9, 307.
[7] Fullerton, M.D. et al. (2013) Nat Med 19, 1649-54.

Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody Preparation Products And Raw materials

Raw materials

Preparation Products

Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Universal Biotech Co.,Ltd 15921930842 15921930842 yh-wang@univ-bio.com China 25021 58
Cell Signaling Technology Inc 21-80243558 86218024 info@cellsignal.cn China 6427 58
Guangzhou Laiye Biotechnology Co., Ltd. 18998805962 CHINA 174 58
Shenzhen Haoman Technology Co., Ltd. 13713773547 CHINA 1473 58
Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody
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