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ChemicalBook >> CAS DataBase List >>4-BOCAMINO-NICOTINIC ACID

4-BOCAMINO-NICOTINIC ACID

CAS No.
171178-34-0
Chemical Name:
4-BOCAMINO-NICOTINIC ACID
Synonyms
4-BOCAMINO-NICOTINIC ACID;4-N-Boc-aminonicotinic acid;4-TERT-BUTOXYCARBONYLAMINO-NICOTINIC ACID;4-Tert-butoxycarbonylamino-nicatinec acid;4-{[(tert-butoxy)carbonyl]aMino}pyridine-3-carboxylic acid;4-[(2-methylpropan-2-yl)oxycarbonylamino]pyridine-3-carboxylic acid;3-Pyridinecarboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-;4-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-pyridinecarboxylic acid
CBNumber:
CB7692761
Molecular Formula:
C11H14N2O4
Molecular Weight:
238.24
MDL Number:
MFCD03427724
MOL File:
171178-34-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:38:02
Product description Number Pack Size Price
4-((tert-Butoxycarbonyl)amino)nicotinic acid 294942 250.00mg $43
4-Boc-aminonicotinic acid ≥95%(NMR) 18979 250MG $124.99
4-((tert-Butoxycarbonyl)amino)nicotinic acid 294942 1.00g $74
4-Boc-aminonicotinic acid ≥95%(NMR) 18979 1G $259.39
4-((tert-Butoxycarbonyl)amino)nicotinic acid 294942 5.00g $265

4-BOCAMINO-NICOTINIC ACID Properties

Boiling point 348.4±27.0 °C(Predicted)
Density 1.293±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka 1.70±0.36(Predicted)
Appearance White to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P261-P280
Hazard Codes  Xi
Risk Statements  43
Safety Statements  36/37

4-BOCAMINO-NICOTINIC ACID price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 294942 4-((tert-Butoxycarbonyl)amino)nicotinic acid 171178-34-0 250.00mg $43 2026-05-19 Buy
Chem-Impex 18979 4-Boc-aminonicotinic acid ≥95%(NMR) 171178-34-0 250MG $124.99 2026-05-19 Buy
Matrix Scientific 294942 4-((tert-Butoxycarbonyl)amino)nicotinic acid 171178-34-0 1.00g $74 2026-05-19 Buy
Chem-Impex 18979 4-Boc-aminonicotinic acid ≥95%(NMR) 171178-34-0 1G $259.39 2026-05-19 Buy
Matrix Scientific 294942 4-((tert-Butoxycarbonyl)amino)nicotinic acid 171178-34-0 5.00g $265 2026-05-19 Buy
Product number Packaging Price Buy
294942 250.00mg $43 Buy
18979 250MG $124.99 Buy
294942 1.00g $74 Buy
18979 1G $259.39 Buy
294942 5.00g $265 Buy

4-BOCAMINO-NICOTINIC ACID Chemical Properties,Uses,Production

Synthesis

Methyl 4-((tert-butoxycarbonyl)aMino)nicotinate

280115-84-6

4-BOCAMINO-NICOTINIC ACID

171178-34-0

General procedure for the synthesis of 4-((tert-butoxycarbonyl)amino)nicotinic acid from methyl 4-((tert-butoxycarbonyl)amino)nicotinate: 4-((tert-butoxycarbonyl)amino)nicotinic acid methyl ester (6.02 g, 23.86 mmol) was dissolved in dioxane (100 mL), and an aqueous sodium hydroxide solution (0.970 N, 28.05 mL, 27.20 mmol ). The reaction mixture was heated to 60°C and held for 1 hr and subsequently cooled to room temperature. To the cooled mixture was added aqueous hydrochloric acid (1.03 M, 26.99 mL, 27.20 mmol) and then extracted with chloroform (5 x 100 mL). The organic phases were combined, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 4-((tert-butoxycarbonyl)amino)nicotinic acid as a creamy solid (4.70 g, 83% yield).

References

[1] Patent: WO2006/100310, 2006, A1. Location in patent: Page/Page column 34
[2] Patent: WO2005/32481, 2005, A2. Location in patent: Page/Page column 42-43

4-BOCAMINO-NICOTINIC ACID Suppliers

Global( 59)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
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Win-Win chemical CO., Limited
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Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 17705817739 info@dycnchem.com China 52704 58
Alfa Chemistry
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GIHI CHEMICALS CO.,LIMITED
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Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501 product@acmec-e.com China 33324 58
Jilin Chinese Academy of Sciences-yanshen Technology
18143011203 info@chemextension.com China 42056 58
Aladdin Scientific
tp@aladdinsci.com United States 52923 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580 cooperation@kean-chem.com China 40066 58
4-BOCAMINO-NICOTINIC ACID 4-TERT-BUTOXYCARBONYLAMINO-NICOTINIC ACID 4-{[(tert-butoxy)carbonyl]aMino}pyridine-3-carboxylic acid 4-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-pyridinecarboxylic acid 3-Pyridinecarboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]- 4-Tert-butoxycarbonylamino-nicatinec acid 4-[(2-methylpropan-2-yl)oxycarbonylamino]pyridine-3-carboxylic acid 4-N-Boc-aminonicotinic acid 171178-34-0
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