Capillarisin
- CAS No.
- 56365-38-9
- Chemical Name:
- Capillarisin
- Synonyms
- Capillaris;CAPILLARISIN;CAPILLARISIN(RG);CAPILLARISIN hplc;Capillarisin std.;Capillarisin Standard;Capillarisin USP/EP/BP;5,7-Dihydroxy-2-(4-hydroxyphenoxy)-6-methoxychromen-4-one;5,7-Dihydroxy-2-(4-hydroxyphenoxy)-6-methoxy-4H-chromen-4-one;5,7-dihydroxy-2-(4-hydroxyphenoxy)-6-methoxy-1-benzopyran-4-one
- CBNumber:
- CB7693122
- Molecular Formula:
- C16H12O7
- Molecular Weight:
- 316.26
- MDL Number:
- MFCD00017728
- MOL File:
- 56365-38-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Capillarisin 99.27% | CS-0080783 | 1mg | $552 |
| Capillarisin 99.27% | CS-0080783 | 5mg | $1571 |
| Capillarisin 99.27% | CS-0080783 | 1mg | $552 |
| Capillarisin 99.27% | CS-0080783 | 5mg | $1571 |
| Capillarisin >98% | AA00ECWI | 1mg | $602 |
| Melting point | approximate 225℃ (dec.) |
|---|---|
| Boiling point | 582.6±50.0 °C(Predicted) |
| Density | 1.551±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 6.37±0.40(Predicted) |
| color | Light yellow to yellow |
Capillarisin price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0080783 | Capillarisin 99.27% | 56365-38-9 | 1mg | $552 | 2026-06-04 | Buy |
| ChemScene | CS-0080783 | Capillarisin 99.27% | 56365-38-9 | 5mg | $1571 | 2026-06-04 | Buy |
| ChemScene | CS-0080783 | Capillarisin 99.27% | 56365-38-9 | 1mg | $552 | 2026-06-04 | Buy |
| ChemScene | CS-0080783 | Capillarisin 99.27% | 56365-38-9 | 5mg | $1571 | 2026-06-04 | Buy |
| aablocks | AA00ECWI | Capillarisin >98% | 56365-38-9 | 1mg | $602 | 2026-05-28 | Buy |
Capillarisin Chemical Properties,Uses,Production
Uses
Capillarisin, as a constituent from Artemisiae Capillaris herba, is found to exert anti-inflammatory and antioxidant properties. Capillarisin can be used for the research of asthma-mediated complications and can be a potential neuroprotectant against bupivacaine-induced neurotoxicity[1][2][3].
Definition
ChEBI: Capillarisin is a member of coumarins.
in vivo
Capillarisin (20 and 80 mg/kg; i.p.; 1 hour) pretreatment strongly inhibits NF-κB mediated genes (iNOS, COX-2)[4].
Capillarisin significantly reduces the plasma leading nitrite production. Capillarisin markedly suppresses the adenosine 5'-triphosphate (ATP) in plasma and substance P in CFA-induced paw tissue[4].
| Animal Model: | ICR mice[4] |
| Dosage: | 20 and 80 mg/kg |
| Administration: | I.p.; 1 hour |
| Result: | Pretreatment strongly inhibited NF-κB mediated genes (iNOS, COX-2). |
target
TLR | NF-kB | MAPK | STAT | TNF-α | IL Receptor | NO | PGE | AP-1 | ERK | NOS | COX | MMP(e.g.TIMP) | VEGFR | JNK | Bcl-2/Bax
References
[1] Peng G, et al. Capillarisin exerts antiasthmatic activity in neonatal rats via modulating the matrix remodeling. Pak J Pharm Sci. 2020;33(4(Supplementary)):1907-1915. PMID:33612476
[2] Komiya T, et al. Capillarisin, a Constituent from Artemisiae Capillaris Herba. Chemical and Pharmaceutical Bulletin, 1975
[3] Zhao T, Wang Q. Capillarisin protects SH-SY5Y cells against bupivacaine-induced apoptosis via ROS-mediated PI3K/PKB pathway. Life Sci. 2020;259:118279. DOI:10.1016/j.lfs.2020.118279
[4] Khan S, et al. Anti-hyperalgesic and anti-allodynic activities of capillarisin via suppression of inflammatory signaling in animal model. J Ethnopharmacol. 2014;152(3):478-486. DOI:10.1016/j.jep.2014.01.028
Capillarisin Preparation Products And Raw materials
Raw materials
Preparation Products
Capillarisin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28675 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33324 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Chengdu Climax Biotech Co., Ltd. | 028-83311324 1278112614 | climaxbiotech@gmail.com | China | 925 | 58 |
