(±)-5-HETE, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution
- CAS No.
- 71030-39-2
- Chemical Name:
- (±)-5-HETE, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution
- Synonyms
- KGIJOOYOSFUGPC-XTDASVJISA-N;(±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution;6,8,11,14-Eicosatetraenoic acid, 5-hydroxy-, (6E,8Z,11Z,14Z)-;(±)-5-HETE, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution
- CBNumber:
- CB82129488
- Molecular Formula:
- C20H32O3
- Molecular Weight:
- 320.47
- MDL Number:
- MFCD00065818
- MOL File:
- 71030-39-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (±)5-HETE ≥95% | 34210 | 25μg | $87 |
| (±)5-HETE ≥95% | 34210 | 50μg | $165 |
| (±)5-HETE ≥95% | 34210 | 100μg | $313 |
| (±)5-HETE ≥95% | 34210 | 25 μg | $72 |
| (±)5-HETE ≥95% | 34210 | 50 μg | $135 |
| Boiling point | 487.7±45.0 °C(Predicted) |
|---|---|
| Density | 0.984±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility |
0.1 M Na2CO3: 2 mg/ml DMF: Miscible DMSO: Miscible Ethanol: MisciblePBS pH 7.2: 0.8 mg/ml |
| pka | 4.67±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
| FDA UNII | 92JQY74TBX |
(±)-5-HETE, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 34210 | (±)5-HETE ≥95% | 71030-39-2 | 25μg | $87 | 2026-04-30 | Buy |
| Cayman Chemical | 34210 | (±)5-HETE ≥95% | 71030-39-2 | 50μg | $165 | 2026-04-30 | Buy |
| Cayman Chemical | 34210 | (±)5-HETE ≥95% | 71030-39-2 | 100μg | $313 | 2026-04-30 | Buy |
| Cayman Chemical | 34210 | (±)5-HETE ≥95% | 71030-39-2 | 25 μg | $72 | 2024-03-01 | Buy |
| Cayman Chemical | 34210 | (±)5-HETE ≥95% | 71030-39-2 | 50 μg | $135 | 2024-03-01 | Buy |
(±)-5-HETE, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution Chemical Properties,Uses,Production
Uses
5-HETE ((±)-5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5(S)-HETE and 5(R)-HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC50 value of 200 nM[1].
Definition
ChEBI: 5-HETE is a HETE having a 5-hydroxy group and (6E)-, (8Z)-, (11Z)- and (14Z)-double bonds. It has a role as a mouse metabolite. It is a conjugate acid of a 5-HETE(1-).
References
[1] J T O'Flaherty, et al. Neutrophil-aggregating activity of monohydroxyeicosatetraenoic acids. Am J Pathol. 1981 Jul;104(1):55-62. PMID:7258296
[2] ZONGYUAN WU, FANG WEI* Analytical Strategy for Oxylipin Annotation by Combining Chemical Derivatization-Based Retention Index Algorithm and Feature Tandem Mass Spectrometric Fragmentation as a Biomarker Discovery Tool[J]. Analytical Chemistry, 2023, 95 43: 15933-15942. DOI: 10.1021/acs.analchem.3c02789
[3] DONG CHENG. MGAT2 inhibitor decreases liver fibrosis and inflammation in murine NASH models and reduces body weight in human adults with obesity.[J]. Cell metabolism, 2022, 34 11: 1732-1748.e5. DOI: 10.1016/j.cmet.2022.10.007
[4] YILIN PANG . LC?MS/MS-based arachidonic acid metabolomics in acute spinal cord injury reveals the upregulation of 5-LOX and COX-2 products[J]. Free Radical Biology and Medicine, 2022, 193: Pages 363-372. DOI: 10.1016/j.freeradbiomed.2022.10.303
[5] ANNE-SOPHIE ARCHAMBAULT. High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients[J]. FASEB Journal, 2021, 35 6. DOI: 10.1096/fj.202100540r
[6] DAVID MERIWETHER. Apolipoprotein A-I mimetics mitigate intestinal inflammation in COX2-dependent inflammatory bowel disease model.[J]. Journal of Clinical Investigation, 2019, 129 9: 3670-3685. DOI: 10.1172/jci123700
[7] JESMOND DALLI. Lipid Mediator Metabolomics Via LC-MS/MS Profiling and Analysis.[J]. Methods in molecular biology, 2018, 1730: 59-72. DOI: 10.1007/978-1-4939-7592-1_4
[8] CARLOS ARTéRIO SORGI. Comprehensive high-resolution multiple-reaction monitoring mass spectrometry for targeted eicosanoid assays[J]. Scientific Data, 2018, 5 1: 1-12. DOI: 10.1038/sdata.2018.167
[9] REBECA CAIRES. Omega-3 Fatty Acids Modulate TRPV4 Function through Plasma Membrane Remodeling.[J]. Cell reports, 2017, 21 1: 246-258. DOI: 10.1016/j.celrep.2017.09.029
[10] RYOHEI AOYAGI. Comprehensive analyses of oxidized phospholipids using a measured MS/MS spectra library.[J]. Journal of Lipid Research, 2017, 58 11: 2229-2237. DOI: 10.1194/jlr.d077123
[11] SWATHI BANTHIYA . Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa[J]. Biochimica et biophysica acta. Molecular and cell biology of lipids, 2016, 1861 11: Pages 1681-1692. DOI: 10.1016/j.bbalip.2016.08.002
[12] HAI-YAN QI. A cytosolic phospholipase A2-initiated lipid mediator pathway induces autophagy in macrophages.[J]. Journal of immunology, 2011, 187 10: 5286-5292. DOI: 10.4049/jimmunol.1004004
(±)-5-HETE, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution Preparation Products And Raw materials
Raw materials
Preparation Products
(±)-5-HETE, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29868 | 58 |
| Cayman Chemical Company | -- | sales@caymanchem.com | China | 6838 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Cayman Chemical Company | 58 |
71030-39-2((±)-5-HETE, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic acid solution)Related Search:
1of4
