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ChemicalBook >> CAS DataBase List >>2-benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine

2-benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine

CAS No.
1104027-46-4
Chemical Name:
2-benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine
Synonyms
2-benzyl-5-chloro-3,4-dihydro-1H-2,6-naphthyridine;2-benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine;5-Chloro-1,2,3,4-tetrahydro-2-(benzyl)-2,6-naphthyridine;5-Chloro-1,2,3,4-tetrahydro-2-(phenylmethyl)-2,6-naphthyridine;2,6-Naphthyridine, 5-chloro-1,2,3,4-tetrahydro-2-(phenylmethyl)-;2-benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine hydrochloride;2,6-Naphthyridine-2(1H)-carboxylic acid, 5-chloro-3,4-dihydro-, 1,1-dimethylethyl ester
CBNumber:
CB82499244
Molecular Formula:
C15H15ClN2
Molecular Weight:
258.75
MDL Number:
MFCD11846202
MOL File:
1104027-46-4.mol
Last updated:2026-05-28 04:26:32
Product description Number Pack Size Price
2-BENZYL-5-CHLORO-1,2,3,4-TETRAHYDRO-2,6-NAPHTHYRIDINE 95% SC2351 0.25G $514
2-BENZYL-5-CHLORO-1,2,3,4-TETRAHYDRO-2,6-NAPHTHYRIDINE 95% SC2351 1G $1284
2-Benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine EUB02746 50mg $358.5
2-Benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine EUB02746 0.5g $1062
2-Benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine 070281 1.00g $1172
More product size

2-benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine Properties

Boiling point 377.5±42.0 °C(Predicted)
Density 1.227
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 5.38±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

2-benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech SC2351 2-BENZYL-5-CHLORO-1,2,3,4-TETRAHYDRO-2,6-NAPHTHYRIDINE 95% 1104027-46-4 0.25G $514 2026-04-30 Buy
AstaTech SC2351 2-BENZYL-5-CHLORO-1,2,3,4-TETRAHYDRO-2,6-NAPHTHYRIDINE 95% 1104027-46-4 1G $1284 2026-04-30 Buy
Biosynth EUB02746 2-Benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine 1104027-46-4 50mg $358.5 2026-06-04 Buy
Biosynth EUB02746 2-Benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine 1104027-46-4 0.5g $1062 2026-06-04 Buy
Matrix Scientific 070281 2-Benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine 1104027-46-4 1.00g $1172 2026-05-18 Buy
Product number Packaging Price Buy
SC2351 0.25G $514 Buy
SC2351 1G $1284 Buy
EUB02746 50mg $358.5 Buy
EUB02746 0.5g $1062 Buy
070281 1.00g $1172 Buy

2-benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine Chemical Properties,Uses,Production

Uses

5-Chloro-1,2,3,4-tetrahydro-2-(phenylmethyl)-2,6-naphthyridine is an intermediate used to prepare substituted naphthyridines as FAAH modulators useful in prevention and treatment of FAAH-mediated diseases.

Synthesis

A round bottom flask was charged with 6-benzyl-5,6,7,8-tetrahydro-2,6-naphthyridin-1-ol (7 g, 29 mmol) and phosphorochloridic acid {LeonidChemicals, India; add 80 mL) and heated to reflux for 16 hours to monitor the progress of the reaction by TLC. Upon completion of the reaction, POCl3 was distilled and the residue was quenched with ice-cold water and then extracted with dichloromethane (3 100 mL). The combined organic layers were dried with anhydrous sodium sulfate and the solvent was removed under reduced pressure. The residue was purified by column chromatography (methanol/dichloromethane, 5:95) to afford the desired product 2-phenylmethyl-5-chloro-1,2,3,4-tetrahydro-[2,6]diazanaphthalene (80% yield).

2-benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 36)Suppliers
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Capot Chemical Co.,Ltd.
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Alchem Pharmtech,Inc.
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Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
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DAYANG CHEM (HANGZHOU) CO.,LTD
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Amadis Chemical Company Limited
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Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18207 66
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10186 62
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16101 64
SynAsst Chemical. 021-60343070 China 12740 55
Xunteng International Trading Co.,Limited China Hong Kong 878 55

1104027-46-4(2-benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine)Related Search:

2-benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine 2-benzyl-5-chloro-1,2,3,4-tetrahydro-2,6-naphthyridine hydrochloride 5-Chloro-1,2,3,4-tetrahydro-2-(phenylmethyl)-2,6-naphthyridine 2-benzyl-5-chloro-3,4-dihydro-1H-2,6-naphthyridine 2,6-Naphthyridine-2(1H)-carboxylic acid, 5-chloro-3,4-dihydro-, 1,1-dimethylethyl ester 2,6-Naphthyridine, 5-chloro-1,2,3,4-tetrahydro-2-(phenylmethyl)- 5-Chloro-1,2,3,4-tetrahydro-2-(benzyl)-2,6-naphthyridine 1104027-46-4 C15H15ClN2ClH Heterocycle-Pyridine series
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