tert-Butyl N-benzyl-N-(2-hydroxyethyl)carbamate
- CAS No.
- 121496-39-7
- Chemical Name:
- tert-Butyl N-benzyl-N-(2-hydroxyethyl)carbamate
- Synonyms
- N-Boc-benzyl-ethanol amine;2-(Benzyl-Boc-amino)ethanol;N-Boc-N-benzyl-ethanolamine;tertbutylbenzylhydroxyethylcarbamate;tert-butyl benzyl(2-hydroxyethyl)carbamate;N-tert.-Butoxycarbonyl-N-benzyl-ethanolamine;tert-Butyl N-benzyl-N-(2-hydroxyethyl)carbamate;Benzyl (2-hydroxyethyl)carbamate tert-butyl ester;Carbamic acid, N-(2-hydroxyethyl)-N-(phenylmethyl)-, 1,1-dimethylethyl ester
- CBNumber:
- CB82527091
- Molecular Formula:
- C14H21NO3
- Molecular Weight:
- 251.32
- MDL Number:
- MFCD14155817
- MOL File:
- 121496-39-7.mol
| Product description | Number | Pack Size | Price |
| tert-Butyl benzyl(2-hydroxyethyl)carbamate 97% | AS114230 | 1g | $121 |
| tert-Butyl benzyl(2-hydroxyethyl)carbamate 97% | AS114230 | 5g | $375 |
| tert-Butyl benzyl(2-hydroxyethyl)carbamate 97% | AS114230 | 25g | $894 |
| tert-Butyl N-benzyl-N-(2-hydroxyethyl)carbamate | 054336 | 1.00g | $63 |
| tert-Butyl N-benzyl-N-(2-hydroxyethyl)carbamate | 054336 | 5.00g | $237 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H412-H319-H335-H315 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P273-P501 |
| HazardClass | IRRITANT |
tert-Butyl N-benzyl-N-(2-hydroxyethyl)carbamate price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS114230 | tert-Butyl benzyl(2-hydroxyethyl)carbamate 97% | 121496-39-7 | 1g | $121 | 2026-06-04 | Buy |
| Activate Scientific | AS114230 | tert-Butyl benzyl(2-hydroxyethyl)carbamate 97% | 121496-39-7 | 5g | $375 | 2026-06-04 | Buy |
| Activate Scientific | AS114230 | tert-Butyl benzyl(2-hydroxyethyl)carbamate 97% | 121496-39-7 | 25g | $894 | 2026-06-04 | Buy |
| Matrix Scientific | 054336 | tert-Butyl N-benzyl-N-(2-hydroxyethyl)carbamate | 121496-39-7 | 1.00g | $63 | 2026-05-18 | Buy |
| Matrix Scientific | 054336 | tert-Butyl N-benzyl-N-(2-hydroxyethyl)carbamate | 121496-39-7 | 5.00g | $237 | 2026-05-18 | Buy |
tert-Butyl N-benzyl-N-(2-hydroxyethyl)carbamate Chemical Properties,Uses,Production
Synthesis
24424-99-5
104-63-2
121496-39-7
General procedure for the synthesis of tert-butyl benzyl (2-hydroxyethyl) carbamate from di-tert-butyl dicarbonate and N-benzylethanolamine: a solution of di-tert-butyl dicarbonate (0.01 mol) in dichloromethane (15 mL) was added slowly and dropwise to a mixture containing 2-benzylaminoethanol (0.01 mol), dichloromethane (15 mL), and a 1 M aqueous sodium hydroxide solution (12 mL). . The reaction mixture was stirred at room temperature for 24 hours. After completion of the reaction, the organic layer was separated, washed sequentially with water (25 mL × 2) and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure to give the crude product as an oil. The crude product was purified by silica gel column chromatography with the eluent of petroleum ether: ethyl acetate (7:3, v/v) to obtain the target product tert-butyl benzyl (2-hydroxyethyl)carbamate in 100% yield.
References
[1] Bioorganic and Medicinal Chemistry Letters, 1998, vol. 8, # 3, p. 295 - 300
[2] Journal of Organic Chemistry, 2000, vol. 65, # 20, p. 6368 - 6380
[3] Patent: WO2005/26111, 2005, A2. Location in patent: Page/Page column 17
[4] Patent: WO2008/42353, 2008, A1. Location in patent: Page/Page column 19; 21
[5] Patent: TW2016/2105, 2016, A. Location in patent: Paragraph 0563
tert-Butyl N-benzyl-N-(2-hydroxyethyl)carbamate Preparation Products And Raw materials
Raw materials
Preparation Products
tert-Butyl N-benzyl-N-(2-hydroxyethyl)carbamate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Beijing FYF Chemicals Co., Ltd | 010-57903446 15869909019 | 168931144@qq.com | China | 2851 | 58 |
| Mashilabs (Shanghai) Co.,Ltd. | 19916721580 | mafarm@126.com | China | 4539 | 58 |
| Shanghai Brain Biotechnology Co., Ltd. | 13564638271 | shhjiang1977@163.com | China | 2994 | 55 |
| Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28769 | 58 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15082 | 58 |
| Shanghai SPAR pharmaceutical technology co., LTD | 021-000000 | admin@jingshipharmatech.com | China | 9839 | 58 |
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