2-Chloro-6-hydroxyquinoline
- CAS No.
- 577967-89-6
- Chemical Name:
- 2-Chloro-6-hydroxyquinoline
- Synonyms
- 2-chloroquinolin-6-ol;2-chloro-6-Quinolinol;6-Quinolinol, 2-chloro-;2-Chloro-6-hydroxyquinoline;577967-89-6
- CBNumber:
- CB82554695
- Molecular Formula:
- C9H6ClNO
- Molecular Weight:
- 179.6
- MDL Number:
- MFCD12405093
- MOL File:
- 577967-89-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Chloroquinolin-6-ol | TRC-C429278-500MG | 500mg | $223 |
| 2-Chloroquinolin-6-ol | TRC-C429278-250MG | 250mg | $144 |
| 2-Chloroquinolin-6-ol | TRC-C429278-100MG | 100mg | $97 |
| 2-Chloroquinolin-6-ol | CYA96789 | 25g | $649 |
| 2-Chloroquinolin-6-ol | CYA96789 | 50g | $908.5 |
| Melting point | 192℃ |
|---|---|
| Boiling point | 342.1±22.0 °C(Predicted) |
| Density | 1.412 |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Acetonitrile (Slightly), DMSO (Slightly) |
| form | Solid |
| pka | 8.62±0.40(Predicted) |
| color | Pale Beige |
| InChI | InChI=1S/C9H6ClNO/c10-9-4-1-6-5-7(12)2-3-8(6)11-9/h1-5,12H |
| InChIKey | XANCOYIVTNZKOE-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC(O)=CC=2)C=CC=1Cl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933499090 |
2-Chloro-6-hydroxyquinoline price More Price(68)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-C429278-500MG | 2-Chloroquinolin-6-ol | 577967-89-6 | 500mg | $223 | 2026-06-03 | Buy |
| TRC | TRC-C429278-250MG | 2-Chloroquinolin-6-ol | 577967-89-6 | 250mg | $144 | 2026-06-03 | Buy |
| TRC | TRC-C429278-100MG | 2-Chloroquinolin-6-ol | 577967-89-6 | 100mg | $97 | 2026-06-03 | Buy |
| Biosynth | CYA96789 | 2-Chloroquinolin-6-ol | 577967-89-6 | 25g | $649 | 2026-06-04 | Buy |
| Biosynth | CYA96789 | 2-Chloroquinolin-6-ol | 577967-89-6 | 50g | $908.5 | 2026-06-04 | Buy |
2-Chloro-6-hydroxyquinoline Chemical Properties,Uses,Production
Uses
2-Chloroquinolin-6-ol can be used for hair dye compositions.
Definition
ChEBI: 2-chloroquinolin-6-ol is a monohydroxyquinoline that is 6-hydroxyquinoline in which the hydrogen at position 2 is replaced by a chlorine. It is an organochlorine compound and a monohydroxyquinoline.
Synthesis
13676-02-3
577967-89-6
The general procedure for the synthesis of 2-chloro-6-hydroxyquinoline from 2-chloro-6-methoxyquinoline is as follows: General method: aryl methyl ether (1.0 eq.) was dissolved in dichloromethane (DCM, 10 mL) and cooled to 0 °C. Boron tribromide (BBr3, 5.0 eq.) was added slowly under stirring. The reaction mixture was stirred at 0 °C and then gradually warmed to room temperature and continued stirring at room temperature for 15 hours. Upon completion of the reaction, the reaction was quenched with sodium bicarbonate (NaHCO3) solution (50 mL) followed by extraction with DCM (4 x 10 mL). The organic layers were combined, washed with water (3 × 10 mL), dried over anhydrous sodium sulfate (Na2SO4), and finally concentrated under vacuum to obtain the target phenolic compounds. 2-Chloro-6-hydroxyquinoline (DHK-6-71) was prepared from 2 g scale of 2-chloro-6-methoxyquinoline using the above general method G. The product was a yellow solid in 93% (1.72 g) yield.
References
[1] Patent: CN102985411, 2016, B. Location in patent: Paragraph 0906-0908
[2] Patent: WO2012/48181, 2012, A1. Location in patent: Page/Page column 74
[3] Patent: WO2012/83165, 2012, A1. Location in patent: Page/Page column 91
[4] ACS Chemical Neuroscience, 2016, vol. 7, # 7, p. 897 - 911
[5] Journal of the American Chemical Society, 1951, vol. 73, p. 4837
2-Chloro-6-hydroxyquinoline Preparation Products And Raw materials
2-Chloro-6-hydroxyquinoline Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | sale03@alfachem.cn | China | 9812 | 58 |
| Labnetwork lnc. | +86-27-50766799 +86-18062016861 | contact@labnetwork.com | China | 19987 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43333 | 58 |
| Sichuan Biosynce Pharmatech Co., Ltd. | diane@biosynce.com | China | 4871 | 58 | |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33324 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
View Lastest Price from 2-Chloro-6-hydroxyquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-09-04 | 2-Chloro-6-hydroxyquinoline
577967-89-6
|
$1.00 | 1KG | 97%-98% | 200KG | Career Henan Chemical Co |
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- 2-Chloro-6-hydroxyquinoline
577967-89-6
- $1.00
- 97%-98%
- Career Henan Chemical Co
