13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4
- CAS No.
- Chemical Name:
- 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4
- Synonyms
- 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4
- CBNumber:
- CB82589871
- Molecular Formula:
- C20H30D4F2O5
- Molecular Weight:
- 396.502413512
- MDL Number:
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 ≥99%deuteratedforms(d1-d4) | 9000406 | 25μg | $84 |
| 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 ≥99%deuteratedforms(d1-d4) | 9000406 | 50μg | $157 |
| 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 ≥99%deuteratedforms(d1-d4) | 9000406 | 100μg | $295 |
| 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 ≥99%deuteratedforms(d1-d4) | 9000406 | 1mg | $2280 |
| 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 ≥99% deuterated forms (d1-d4) | 9000406 | 25μg | $76 |
13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 9000406 | 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 ≥99%deuteratedforms(d1-d4) | 25μg | $84 | 2026-04-30 | Buy | |
| Cayman Chemical | 9000406 | 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 ≥99%deuteratedforms(d1-d4) | 50μg | $157 | 2026-04-30 | Buy | |
| Cayman Chemical | 9000406 | 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 ≥99%deuteratedforms(d1-d4) | 100μg | $295 | 2026-04-30 | Buy | |
| Cayman Chemical | 9000406 | 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 ≥99%deuteratedforms(d1-d4) | 1mg | $2280 | 2026-04-30 | Buy | |
| Cayman Chemical | 9000406 | 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 ≥99% deuterated forms (d1-d4) | 25μg | $76 | 2024-03-01 | Buy |
13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 Chemical Properties,Uses,Production
Description
PGE1 is produced by the metabolism of dihomo-γ-linolenic acid (DGLA) by the cyclooxygenase pathway. PGE1 inhibits platelet aggregation (IC50 = 40 nM) and increases vasodilation.1,213,14-dihydro-16,16-difluoro PGE1 is a biologically active metabolite of PGE1, inhibiting platelet aggregation with comparable potency to the parent compound.3,2 The addition of two electron-withdrawing fluorine atoms, which should stabilize the molecule against hydrolytic cleavage, may be expected to delay degradation in vivo.4 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro PGE1-3,3’,4,4’-d4) contains four deuterium atoms at the 3, 3’, 4, and 4’ positions. It is intended for use as an internal standard for the quantification of 13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1 by GC- or LC-mass spectrometry (MS).WARNING This product is not for human or veterinary use.
References
[1] I. J?RVING. ANTIAGGREGATING POTENCY OF E-TYPE PROSTAGLANDINS IN HUMAN AND RABBIT PLATELETS[J]. Proceedings of the Estonian Academy of Sciences. Chemistry, 1991, 32 1. DOI: 10.3176/chem.1991.3.09
[2] WESTWICK J. The effect of pulmonary metabolites of prostaglandins E1, E2 and F2alpha on ADP-induced aggregation of human and rabbit platelets [proceedings].[J]. British Journal of Pharmacology, 1976, 58 2: 297P-298P.
[3] B A PESKAR. On the metabolism of prostaglandin E1 administered intravenously to human volunteers.[J]. Journal of Physiology and Pharmacology, 1991, 42 3: 327-331.
[4] Y HATANO. Vascular relaxing activity and stability studies of 10,10-difluoro-13,14-dehydroprostacyclin.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1980, 77 11: 6846-6850. DOI: 10.1073/pnas.77.11.6846
13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 Preparation Products And Raw materials
Raw materials
Preparation Products
13,14-dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChemeGen | 18818260767 | 2625930290@qq.com | China | 6973 | 58 |
| Cayman Chemical Company | -- | sales@caymanchem.com | China | 6838 | 58 |
| Santa Cruz Biotechnology Inc | -- | scbt@scbt.com | China | 6594 | 58 |
| Supplier | Advantage |
|---|---|
| ChemeGen | 58 |
| Cayman Chemical Company | 58 |
| Santa Cruz Biotechnology Inc | 58 |
