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Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]-

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- structure

CAS No.: 1034305-17-3

Chemical Name:: Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]-

Synonyms: 2-(5-BroMo-2-fluorobenzyl)benzothiophene;2-(5-BroMo-2-fluorobenzyl)benzo[b]thiophene;Ipragliflozin-004;Azilsartan Impurity 64;Ipragliflozin Impurity B;Ipragliflozin Impurity 9;Ipragliflozin intermediate 1;Ipragliflozin impurity B (B4);2-[(5-broMo-2-fluorophenyl)Methyl]-;2-(5-Eromo-2-fluorobenzyl)benzobthiophene

CBNumber:: CB82652155

Molecular Formula:: C15H10BrFS

Molecular Weight:: 321.21

MDL Number:: MFCD28144826

MOL File:: 1034305-17-3.mol

MSDS File:: SDS

Last updated:2026-01-07 11:19:19

Product description	Number	Pack Size	Price
2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 97%	B58108	100mg	$30
2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 97%	B58108	250mg	$40
2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 97%	B58108	1g	$70
2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 97%	B58108	5g	$150
2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 97%	B58108	10g	$370
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Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- Properties

Boiling point	408.9±35.0 °C(Predicted)
Density	1.509±0.06 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
Appearance	White to off-white Solid
InChI	InChI=1S/C15H10BrFS/c16-12-5-6-14(17)11(7-12)9-13-8-10-3-1-2-4-15(10)18-13/h1-8H,9H2
InChIKey	IKGTVOQAJKYBGO-UHFFFAOYSA-N
SMILES	C12=CC=CC=C1C=C(CC1=CC(Br)=CC=C1F)S2

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Synthonix	B58108	2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 97%	1034305-17-3	100mg	$30	2026-05-06	Buy
Synthonix	B58108	2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 97%	1034305-17-3	250mg	$40	2026-05-06	Buy
Synthonix	B58108	2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 97%	1034305-17-3	1g	$70	2026-05-06	Buy
Synthonix	B58108	2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 97%	1034305-17-3	5g	$150	2026-05-06	Buy
Synthonix	B58108	2-(5-Bromo-2-fluorobenzyl)benzo[b]thiophene 97%	1034305-17-3	10g	$370	2026-05-06	Buy

Product number	Packaging	Price	Buy
B58108	100mg	$30	Buy
B58108	250mg	$40	Buy
B58108	1g	$70	Buy
B58108	5g	$150	Buy
B58108	10g	$370	Buy

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- Chemical Properties,Uses,Production

Uses

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- is mainly used in medicine and organic synthesis.

Synthesis

Benzo[b]thiophene-2-Methanol, α-(5-broMo-2-fluorophenyl)-

1034305-11-7

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]-

1034305-17-3

General procedure for the synthesis of 2-(5-bromo-2-fluorobenzyl)benzo[b]thiophene from benzo[b]thiophen-2-yl(5-bromo-2-fluorophenyl)methanol: 35.4 g (105 mmol) of benzo[b]thiophene-2-yl(5-bromo-2-fluorophenyl)methanol, a compound of Formula 3, was dissolved in 800 mL of dichloromethane, and the solution was cooled to -20 °C. To this solution, 36.5 mL (230 mmol) of triethylsilane and 15.2 mL (120 mmol) of boron trifluoride ethyl ether compound were slowly added under stirring. The reaction mixture was kept stirred at -20°C for 30 minutes. Upon completion of the reaction, saturated aqueous sodium bicarbonate solution was added to the mixture to neutralize the reaction. The organic phase was separated, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to remove the solvent. The resulting crude product was purified by column chromatography (eluent: ethyl acetate/hexane mixed solvent) to afford the target product 2-(5-bromo-2-fluorobenzyl)benzo[b]thiophene (Compound 4) 30.4 g, with 99.5% purity and 90.1% yield.

References

[1] Patent: CN108276396, 2018, A. Location in patent: Paragraph 0041; 0048; 0049; 0064; 0079
[2] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 10, p. 3263 - 3279
[3] Patent: CN108623558, 2018, A. Location in patent: Paragraph 0042; 0044; 0046; 0048; 0050; 0052; 0054; 0056

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- Preparation Products And Raw materials

Raw materials

Benzo[b]thiophene-2-Methanol, α-(5-broMo-2-fluorophenyl)- Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)chloroMethyl]- Triethylsilane Boron trifluoride diethyl etherate Dichloromethane

Preparation Products

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- Suppliers

Global( 169)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ANHUI CHICO CHEMICAL CO., LTD.	13057662806	kirsten@chicopharm.com	China	2620	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21585	55
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
Nanjing Finetech Chemical Co., Ltd.	025-85710122 17714198479	sales@fine-chemtech.com	CHINA	885	55
Anqing Chico Pharmaceutical Co., Ltd.	15380796838	chloewu@chicopharm.cn	CHINA	340	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29812	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	965	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58

Supplier	Advantage
ANHUI CHICO CHEMICAL CO., LTD.	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Yingrui Biopharma Co., Ltd.	60
Nanjing Finetech Chemical Co., Ltd.	55
Anqing Chico Pharmaceutical Co., Ltd.	58
career henan chemical co	58
Biochempartner	58
Shenzhen Nexconn Pharmatechs Ltd	58

View Lastest Price from Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-04	2-(5-Bromo-2-fluorobenzyl)benzothiophene 1034305-17-3		1kg	99%	100mt/year	Jinan Finer Chemical Co., Ltd
2025-11-18	Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- 1034305-17-3	$1.10	1g	99.0% Min	100 Tons	Dideu Industries Group Limited
2025-04-04	2-(5-Bromo-2-fluorobenzyl)benzothiophene 1034305-17-3		1KG	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

2-(5-Bromo-2-fluorobenzyl)benzothiophene
1034305-17-3
$0.00
99%
Jinan Finer Chemical Co., Ltd

Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]-
1034305-17-3
$1.10
99.0% Min
Dideu Industries Group Limited

2-(5-Bromo-2-fluorobenzyl)benzothiophene
1034305-17-3
98%
Henan Aochuang Chemical Co.,Ltd.

1034305-17-3(Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]-)Related Search:

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2-(5-bromo-2-fluorobenzyl)-1-benzothiophene 2-[(5-bromo-2-fluorophenyl)methyl]-1-benzothiophene Ipragliflozin impurity B (B4) 2-[(5-broMo-2-fluorophenyl)Methyl]- Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- 2-[(5-bromo-2-fluorophenyl)Methyl]-Benzo[b]thiophene Ipragliflozin-004 Ipragliflozin Impurity B Ipragliflozin intermediate 1 Benzo[b]thiophene, 2-[(5-broMo-2-fluorophenyl)Methyl]- ISO 9001：2015 REACH Azilsartan Impurity 64 2-(5-BroMo-2-fluorobenzyl)benzothiophene Ipragliflozin Impurity 9 2-(5-Eromo-2-fluorobenzyl)benzobthiophene 2-(5-BroMo-2-fluorobenzyl)benzo[b]thiophene 1034305-17-3 C15H10BrFS

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