O-Propargyl-PuroMycin
- CAS No.
- 1416561-90-4
- Chemical Name:
- O-Propargyl-PuroMycin
- Synonyms
- O-Propargyl-PuroMycin;O-propargyl-puromycin (OPP);O-Propargyl-Puromycin, 10 mM in DMSO;O-propargyl-puromycine (OPP) (CCT-1407);OPropargylPuromycin,O Propargyl Puromycin;O-Propargylpuromycin, protein marker for imaging;Adenosine, 3'-[[(2S)-2-amino-1-oxo-3-[4-(2-propyn-1-yloxy)phenyl]propyl]amino]-3'-deoxy-N,N-dimethyl-
- CBNumber:
- CB82668514
- Molecular Formula:
- C24H29N7O5
- Molecular Weight:
- 495.53
- MDL Number:
- MFCD28386284
- MOL File:
- 1416561-90-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| O-Propargyl-puromycin ≥98% | 15134 | 500μg | $208 |
| O-Propargyl-puromycin ≥98% | 15134 | 1mg | $374 |
| O-Propargyl-puromycin | 15134 | 500μg | $189 |
| O-Propargyl-puromycin | 15134 | 1mg | $340 |
| O-Propargyl-puromycin (OPP) | CRB7108418 | 5mg | $990 |
O-Propargyl-PuroMycin price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 15134 | O-Propargyl-puromycin ≥98% | 1416561-90-4 | 500μg | $208 | 2026-04-30 | Buy |
| Cayman Chemical | 15134 | O-Propargyl-puromycin ≥98% | 1416561-90-4 | 1mg | $374 | 2026-04-30 | Buy |
| Cayman Chemical | 15134 | O-Propargyl-puromycin | 1416561-90-4 | 500μg | $189 | 2024-03-01 | Buy |
| Cayman Chemical | 15134 | O-Propargyl-puromycin | 1416561-90-4 | 1mg | $340 | 2024-03-01 | Buy |
| Biosynth | CRB7108418 | O-Propargyl-puromycin (OPP) | 1416561-90-4 | 5mg | $990 | 2026-06-04 | Buy |
O-Propargyl-PuroMycin Chemical Properties,Uses,Production
Uses
O-Propargyl-Puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-Propargyl-Puromycin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
in vivo
Tissues from uninjected mice shows low nonspecific staining, whereas tissues from O-propargyl-puromycin-injected mice display specific patterns of O-propargyl-puromycin incorporation into nascent proteins. In the small intestine, translation is strongest in cells in the crypts and at the base of intestinal villi, consistent with the high proliferative and secretory activity of these cells. The stain is particularly strong in Paneth cells, which are located close to the base of the crypts and are filled with secretory vesicles. The intense O-propargyl-puromycin labeling of vesicles in Paneth cells suggests that prematurely terminated, O-propargyl-puromycin-conjugated secretory proteins are translocated into the endoplasmic reticulum (ER) lumen[1].
storage
Store at -20°C
References
[1] Liu J, et al. Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin. Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):413-8. DOI:10.1073/pnas.1111561108
O-Propargyl-PuroMycin Preparation Products And Raw materials
Raw materials
Preparation Products
O-Propargyl-PuroMycin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39039 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9248 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9804 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847 13636370518 | shyysw007@163.com | China | 89686 | 60 |
| BOC Sciences | 16314854226 | inquiry@bocsci.com | United States | 9713 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
View Lastest Price from O-Propargyl-PuroMycin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-26 | O-Propargyl-Puromycin
1416561-90-4
|
$66.00-248.00 | 99.45% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-05-26 | O-Propargyl-Puromycin
1416561-90-4
|
$66.00-248.00 | 99.45% | 10g | TargetMol Chemicals Inc. |
-
- O-Propargyl-Puromycin
1416561-90-4
- $66.00-248.00
- 99.45%
- TargetMol Chemicals Inc.
-
- O-Propargyl-Puromycin
1416561-90-4
- $66.00-248.00
- 99.45%
- TargetMol Chemicals Inc.
