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ChemicalBook >> CAS DataBase List >>2-AMINOTEREPHTHALIC ACID

2-AMINOTEREPHTHALIC ACID

CAS No.
10312-55-7
Chemical Name:
2-AMINOTEREPHTHALIC ACID
Synonyms
H2ABDC;2-AMINOBENZENE-1,4-DICARBOXYLIC ACID;2-AMINO-1,4-BENZENEDICARBOXYLIC ACID;2,5-Dicarboxyaniline;2-AMINOTEREPHTHALATE;3-aminoterephthalic acid;DK7275;DK7418;JACS-10312-55-7;2-AminoterephthaL
CBNumber:
CB8275813
Molecular Formula:
C8H7NO4
Molecular Weight:
181.15
MDL Number:
MFCD00134536
MOL File:
10312-55-7.mol
MSDS File:
SDS
Last updated:2026-07-31 17:49:05
Product description Number Pack Size Price
2-Aminoterephthalic acid 99% 381071 25g $132
2-Aminoterephthalic Acid A1291 5G $31
2-Aminoterephthalic Acid >98.0%(HPLC)(T) A1291 25g $93
2-Aminoterephthalic acid FA62841 0.1kg $220
2-Aminoterephthalic acid FA62841 0.25kg $395.31
More product size

2-AMINOTEREPHTHALIC ACID Properties

Melting point 324 °C (dec.) (lit.)
Boiling point 314.24°C (rough estimate)
Density 1.4283 (rough estimate)
refractive index 1.5468 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 3.95±0.10(Predicted)
form Granular Powder
color Yellow
Water Solubility Slightly soluble in water.
BRN 2805625
InChI InChI=1S/C8H7NO4/c9-6-3-4(7(10)11)1-2-5(6)8(12)13/h1-3H,9H2,(H,10,11)(H,12,13)
InChIKey GPNNOCMCNFXRAO-UHFFFAOYSA-N
SMILES C1(C(O)=O)=CC=C(C(O)=O)C=C1N
CAS DataBase Reference 10312-55-7(CAS DataBase Reference)
UNSPSC Code 12352106
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
Hazard Note  Irritant
HS Code  29224999
NFPA 704
1
2 0

2-AMINOTEREPHTHALIC ACID price More Price(83)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 381071 2-Aminoterephthalic acid 99% 10312-55-7 25g $132 2026-04-30 Buy
TCI Chemical A1291 2-Aminoterephthalic Acid 10312-55-7 5G $31 2026-04-30 Buy
TCI Chemical A1291 2-Aminoterephthalic Acid >98.0%(HPLC)(T) 10312-55-7 25g $93 2026-04-30 Buy
Biosynth FA62841 2-Aminoterephthalic acid 10312-55-7 0.1kg $220 2026-06-04 Buy
Biosynth FA62841 2-Aminoterephthalic acid 10312-55-7 0.25kg $395.31 2026-06-04 Buy
Product number Packaging Price Buy
381071 25g $132 Buy
A1291 5G $31 Buy
A1291 25g $93 Buy
FA62841 0.1kg $220 Buy
FA62841 0.25kg $395.31 Buy

2-AMINOTEREPHTHALIC ACID Chemical Properties,Uses,Production

Chemical Properties

slight yellow crystalline powder

Uses

2-Aminoterephthalic acid is used as a pharmaceutical intermediate.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

Nitroterephthalic acid

610-29-7

2-AMINOTEREPHTHALIC ACID

10312-55-7

General procedure for the synthesis of 2-aminoterephthalic acid from 2-nitroterephthalic acid: in typical experiments, a mixture of nitroaromatic compounds (1.0 mmol), ammonium formate (3.3 mmol, 208 mg, 1.1 eq.), palladium catalyst (10% Pd/C, 2 mol%, 21 mg), and silicon dioxide (175 mg) was ball-milled in the presence of anhydrous methanol (η= 0.25 μL/mg) was ball-milled for 90 min in the presence of anhydrous methanol (η= 0.25 μL/mg). Upon completion of the milling, a small amount (~1 mg) of the crude reaction mixture was suspended in methanol and analyzed by thin-layer chromatography (TLC, usually using a solvent mixture of dichloromethane: methanol = 20:1 as eluent). The crude product was placed in a well-ventilated fume hood overnight, then suspended in methanol and filtered through a Büchner funnel. The filtrate is evaporated to give the target product 2-aminoterephthalic acid. If necessary, the final product can be further purified by column chromatography.

References

[1] Journal of Organic Chemistry, 1988, vol. 53, # 18, p. 4209 - 4218
[2] Molecules, 2018, vol. 23, # 12,
[3] Farmaco, Edizione Scientifica, 1984, vol. 39, # 11, p. 968 - 978
[4] Patent: CN103664684, 2016, B. Location in patent: Paragraph 0039
[5] Chemische Berichte, 1877, vol. 10, p. 145

610-29-7
10312-55-7
Synthesis of 2-AMINOTEREPHTHALIC ACID from Nitroterephthalic acid
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2-AMINOTEREPHTHALIC ACID pictures 2026-08-07 2-AMINOTEREPHTHALIC ACID
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1kg/bag ≥98% 50 T/Month Hebei Qujie Technology Co., Ltd.
2-AMINOTEREPHTHALIC ACID pictures 2026-08-06 2-AMINOTEREPHTHALIC ACID
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$5.00 1KG 98% Henan Fengda Chemical Co., Ltd
	2,4-2-AMINOTEREPHTHALIC ACID pictures 2026-08-06 2,4-2-AMINOTEREPHTHALIC ACID
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$1.00-6.00 1KG 99% Henan Fengda Chemical Co., Ltd
2-AMINOTEREPHTHALIC ACID TIMTEC-BB SBB006751 2-Aminoterephthalic acid, 99+% Aminoterephthalicacid 2-Aminobenzene-1,4-dicarboxylic acid, 2,5-Dicarboxyaniline 2-AMinoterephthalic acid, 99+% 25GR 2-AMinoterephthalic acid, vzorka 2-AMinoterephthalic acid 99% 2-Aminophthalic acid JACS-10312-55-7 2-AminoterephthaL 2-Aminoterephthalic Acid > 2-Aminoterephthalic Acid,>98% 1,4-Benzenedicarboxylic acid, 2-amino- Dimethyl 5-bromo terephthalate 2-AMINOTEREPHTHALIC ACID USP/EP/BP 2,5-Dicarboxyaniline DK7275 DK7418 2-Aminoterephthalic acid (2-ATA) 2,4-2-AMINOTEREPHTHALIC ACID (2-Bromo-5-methoxy-9-methyl-phenyl)-methano 2-AMINOBENZENE-1,4-DICARBOXYLIC ACID 2-AMINO-1,4-BENZENEDICARBOXYLIC ACID 2-AMINOTEREPHTHALATE 3-aminoterephthalic acid H2ABDC 10312-55-7 H2NC6H314CO2H2 Unnatural Amino Acid Derivatives Specialty Synthesis Peptide Synthesis Aromatic Amino Acids Aromatic Amino Acids Peptide Synthesis Unnatural Amino Acid Derivatives Phthalic Acids, Esters and Derivatives Derivatives of phthalic acid 10312-55-7
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