3-Chlorocinnamic acid
- CAS No.
- 1866-38-2
- Chemical Name:
- 3-Chlorocinnamic acid
- Synonyms
- (E)-3-(3-CHLOROPHENYL)ACRYLIC ACID;3-(3-Chlorophenyl)acrylic acid;AURORA 22720;AKOS BBS-00006453;RARECHEM BK HC T320;3-Chlorociamic acid;3-Chlorocinamic acid;M-CHLOROCINNAMIC ACID;3-Chlorocinnamic acid;3-ChlorocinnamicAcid>
- CBNumber:
- CB8361088
- Molecular Formula:
- C9H7ClO2
- Molecular Weight:
- 182.6
- MDL Number:
- MFCD00004384
- MOL File:
- 1866-38-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Chlorocinnamic Acid >98.0%(T) | C0975 | 25g | $56 |
| 3-Chlorocinnamic acid | FC71049 | 250g | $150 |
| 3-Chlorocinnamic acid | FC71049 | 100g | $150 |
| 3-Chlorocinnamic acid | FC71049 | 500g | $170 |
| 3-Chlorocinnamic acid 95% | J58167 | 5g | $21 |
| More product size | |||
| Melting point | 161-164 °C(lit.) |
|---|---|
| Boiling point | 326.2±25.0 °C(Predicted) |
| Density | 1.332±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 4.29(at 25℃) |
| color | White to Almost white |
| BRN | 2207378 |
| CAS DataBase Reference | 1866-38-2(CAS DataBase Reference) |
| NIST Chemistry Reference | m-Chlorocinnamic acid(1866-38-2) |
| EPA Substance Registry System | 2-Propenoic acid, 3-(3-chlorophenyl)- (1866-38-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26-37 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29163990 | |||||||||
| NFPA 704 |
|
3-Chlorocinnamic acid price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C0975 | 3-Chlorocinnamic Acid >98.0%(T) | 1866-38-2 | 25g | $56 | 2026-04-30 | Buy |
| Biosynth | FC71049 | 3-Chlorocinnamic acid | 1866-38-2 | 250g | $150 | 2026-06-04 | Buy |
| Biosynth | FC71049 | 3-Chlorocinnamic acid | 1866-38-2 | 100g | $150 | 2026-06-04 | Buy |
| Biosynth | FC71049 | 3-Chlorocinnamic acid | 1866-38-2 | 500g | $170 | 2026-06-04 | Buy |
| AK Scientific | J58167 | 3-Chlorocinnamic acid 95% | 1866-38-2 | 5g | $21 | 2026-06-04 | Buy |
3-Chlorocinnamic acid Chemical Properties,Uses,Production
Chemical Properties
white crystalline powder or crystals
Synthesis
141-82-2
587-04-2
1866-38-2
GENERAL METHOD: Under stirring conditions, 6.76 g (65 mmol) of malonic acid was dissolved in a mixed solution of 5 mL of pyridine and 0.5 mL of piperidine. Subsequently, 3-chlorobenzaldehyde (50 mmol) was slowly added at 85°C. The reaction mixture was stirred continuously for 6 hours, during which the progress of the reaction was monitored by thin layer chromatography (TLC) to confirm complete consumption of the feedstock. Upon completion of the reaction, the mixture was cooled to room temperature and neutralized with 10% hydrochloric acid solution under ice bath conditions, at which point a white solid was observed to precipitate. The solid product was collected by filtration and washed three times with ice water to remove impurities. Finally, the target product 3-chlorocinnamic acid (2a-h) was obtained by recrystallization and purification using aqueous ethanol (1:1, v/v).
References
[1] Journal of Organic Chemistry, 2009, vol. 74, # 23, p. 9152 - 9157
[2] Journal of Chemical Research, 2005, # 6, p. 364 - 365
[3] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 7, p. 1849 - 1853
[4] Proceedings - Indian Academy of Sciences, Section A, 1941, vol. 14, p. 116 - 120
[5] Chem.Abstr., 1942, p. 1599
3-Chlorocinnamic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29792 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34563 | 58 |
| Shanghai UCHEM Inc. | +86-18930848214 +86-021-56762820 | sales@myuchem.com | China | 8834 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9996 | 58 |
View Lastest Price from 3-Chlorocinnamic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 3-Chlorocinnamic acid
1866-38-2
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2020-01-09 | 3-Chlorocinnamic acid
1866-38-2
|
$3.00 | 1KG | 98% | 200KG | Career Henan Chemical Co |
-
- 3-Chlorocinnamic acid
1866-38-2
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3-Chlorocinnamic acid
1866-38-2
- $3.00
- 98%
- Career Henan Chemical Co
