5-Amino-1,3-dihydro-2H-benzimidazol-2-one
- CAS No.
- 95-23-8
- Chemical Name:
- 5-Amino-1,3-dihydro-2H-benzimidazol-2-one
- Synonyms
- 5-AMINOBENZIMIDAZOLONE;5(6)-AMINOBENZOIMIDAZOLONE;5-AMINO-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE;7-AMINO-3,4-DIHYDRO-1H-QUINOXALIN-2-ONE;AKOS BBS-00006487;5-Nitro benzimidazolone;Ilaprazole Impurity 170;5-AMINOBENZIMIDAZOLINONE;5-Aminobenzimidazolone,98%;5-AMino-2-enziMidazolinone
- CBNumber:
- CB8410489
- Molecular Formula:
- C7H7N3O
- Molecular Weight:
- 149.15
- MDL Number:
- MFCD00053555
- MOL File:
- 95-23-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Amino-1,3-dihydro-2H-benzimidazol-2-one Aldrich | CDS003171 | 1g | $93.2 |
| 5-Amino-2-benzimidazolinone >98.0%(HPLC) | A1950 | 5g | $17 |
| 5-Amino-2-benzimidazolinone >98.0%(HPLC) | A1950 | 25g | $22 |
| 5-Amino-2-benzimidazolinone Asreported | 258595 | 1kg | $505 |
| 5-Amino-2-benzimidazolinone Asreported | 258595 | 500g | $509 |
| More product size | |||
| Melting point | >300 °C |
|---|---|
| Boiling point | 201.4±19.0 °C(Predicted) |
| Density | 1.363±0.06 g/cm3(Predicted) |
| vapor pressure | 0.001Pa at 20℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | Powder |
| pka | 11.80±0.30(Predicted) |
| color | White to Amber to Dark purple |
| InChI | InChI=1S/C7H7N3O/c8-4-1-2-5-6(3-4)10-7(11)9-5/h1-3H,8H2,(H2,9,10,11) |
| InChIKey | BCXSVFBDMPSKPT-UHFFFAOYSA-N |
| SMILES | C1(=O)NC2=CC=C(N)C=C2N1 |
| LogP | -0.33 at 23℃ and pH6.5-7.5 |
| CAS DataBase Reference | 95-23-8(CAS DataBase Reference) |
| FDA UNII | 3V3FDT3X0M |
| EPA Substance Registry System | 2H-Benzimidazol-2-one, 5-amino-1,3-dihydro- (95-23-8) |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319 |
| Precautionary statements | P305+P351+P338 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-36-22 |
| Safety Statements | 26-36/37/39 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HazardClass | IRRITANT |
| HS Code | 2933998090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 |
| REACH Registrations | Active |
5-Amino-1,3-dihydro-2H-benzimidazol-2-one price More Price(85)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS003171 | 5-Amino-1,3-dihydro-2H-benzimidazol-2-one Aldrich | 95-23-8 | 1g | $93.2 | 2026-04-30 | Buy |
| TCI Chemical | A1950 | 5-Amino-2-benzimidazolinone >98.0%(HPLC) | 95-23-8 | 5g | $17 | 2026-04-30 | Buy |
| TCI Chemical | A1950 | 5-Amino-2-benzimidazolinone >98.0%(HPLC) | 95-23-8 | 25g | $22 | 2026-04-30 | Buy |
| Usbiological | 258595 | 5-Amino-2-benzimidazolinone Asreported | 95-23-8 | 1kg | $505 | 2026-06-03 | Buy |
| Usbiological | 258595 | 5-Amino-2-benzimidazolinone Asreported | 95-23-8 | 500g | $509 | 2026-06-03 | Buy |
5-Amino-1,3-dihydro-2H-benzimidazol-2-one Chemical Properties,Uses,Production
Chemical Properties
Crystalline powder
Uses
5-Amino-2-hydroxybenzimidazole is an important reagent in the discovery of potent and selective non-nucleotide small molecule inhibitors of CD73
Synthesis
93-84-5
95-23-8
Step: 21b Synthesis of 5-amino-1,3-dihydrobenzimidazol-2-one. Pd/C catalyst (140 mg) was added to a mixed solution of methanol and ethyl acetate containing 5-nitro-1,3-dihydrobenzimidazol-2-one (1.4 g, 7.8 mmol) and the hydrogenation reaction was carried out for 6 hours. The progress of the reaction was monitored by thin layer chromatography (TLC, the unfolding agent was a chloroform solution of 10% methanol). After completion of the reaction, the reaction mixture was filtered through a bed of diatomaceous earth and the filtrate was concentrated to give the target product 5-amino-1,3-dihydrobenzimidazol-2-one (1 g, 86% yield).
References
[1] Patent: WO2012/59932, 2012, A1. Location in patent: Page/Page column 161-162
[2] Patent: WO2009/42907, 2009, A1. Location in patent: Page/Page column 78-79
[3] Journal of the American Chemical Society, 1958, vol. 80, p. 1662
[4] Patent: WO2012/115479, 2012, A2. Location in patent: Page/Page column 23
[5] Patent: CN104151251, 2017, B. Location in patent: Paragraph 0024
5-Amino-1,3-dihydro-2H-benzimidazol-2-one Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5229 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16512 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| QINGDAO HONG JIN CHEMCIAL CO.,LTD. | +86-86-532-83657313 +86-18663969289 | hjt@hong-jin.com | China | 225 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 5-Amino-1,3-dihydro-2H-benzimidazol-2-one manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | 5-Amino-1,3-dihydro-2H-benzimidazol-2-one
95-23-8
|
$10.00-30.00 | 10kg | 99% | 100000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-04-17 | 5-Amino-1,3-dihydro-2H-benzimidazol-2-one
95-23-8
|
$3.00-9.00 | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |||
 |
2021-07-13 | 5-Amino-1,3-dihydro-2H-benzimidazol-2-one
95-23-8
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 5-Amino-1,3-dihydro-2H-benzimidazol-2-one
95-23-8
- $10.00-30.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 5-Amino-1,3-dihydro-2H-benzimidazol-2-one
95-23-8
- $3.00-9.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 5-Amino-1,3-dihydro-2H-benzimidazol-2-one
95-23-8
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
