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IQGAP1 antibody

CAS No.
Chemical Name:
IQGAP1 antibody
Synonyms
IQGAP1 antibody
CBNumber:
CB85648326
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Product description Number Pack Size Price
IQGAP1 Antibody orb622692 50μl $400
IQGAP1 Antibody orb622692 100μl $540
IQGAP1 Antibody orb380108 100μl $360
IQGAP1 antibody Affinity purified by Protein A orb10931 200μg $673.2
IQGAP1 antibody Affinity purified by Protein A orb10931 100μg $421.6

IQGAP1 antibody price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biorbyt Ltd orb622692 IQGAP1 Antibody 50μl $400 2026-05-06 Buy
Biorbyt Ltd orb622692 IQGAP1 Antibody 100μl $540 2026-05-06 Buy
Biorbyt Ltd orb380108 IQGAP1 Antibody 100μl $360 2026-05-06 Buy
Biorbyt Ltd orb10931 IQGAP1 antibody Affinity purified by Protein A 200μg $673.2 2021-12-16 Buy
Biorbyt Ltd orb10931 IQGAP1 antibody Affinity purified by Protein A 100μg $421.6 2021-12-16 Buy
Product number Packaging Price Buy
orb622692 50μl $400 Buy
orb622692 100μl $540 Buy
orb380108 100μl $360 Buy
orb10931 200μg $673.2 Buy
orb10931 100μg $421.6 Buy

IQGAP1 antibody Chemical Properties,Uses,Production

Source

Rabbit

Reactivity

Human;Mouse;Rat;Hamster;Monkey

Background

IQGAPs are scaffolding proteins involved in mediating cytoskeletal function. They contain multiple protein interaction domains and bind to a growing number of molecules including actin, myosin light chain, calmodulin, E-cadherin, and β-catenin. Through their GAP-related domains, they bind the small GTPases Rac1 and cdc42. IQGAPs lack GAP activity, however, and regulate small GTPases by stabilizing their GTP-bound forms. Research studies have shown that the function and distribution of the IQGAP proteins widely vary. IQGAP1 is ubiquitously expressed and has been found to interact with APC and the CLIP170 complex in response to small GTPases, promoting cell polarization and migration. Additional research studies have suggested that IQGAP1 could play a part in the invasiveness of some cancers. IQGAP2, which is about 60% identical to IQGAP1, is expressed primarily in liver, but lower levels have been detected in the prostate, kidney, thyroid, stomach, and testis. Research studies have shown that IQGAP2 displays tumor suppressor properties. Less is known about the function of IQGAP3, but this protein is present in the lung, brain, small intestine, and testis and is only expressed in proliferating cells, suggesting a role in cell growth and division.

References

[1] Briggs, M.W. and Sacks, D.B. (2003) EMBO Rep 4, 571-4.
[2] Ho, Y.D. et al. (1999) J Biol Chem 274, 464-70.
[3] Brill, S. et al. (1996) Mol Cell Biol 16, 4869-78.
[4] Watanabe, T. et al. (2004) Dev Cell 7, 871-83.
[5] Fukata, M. et al. (2002) Cell 109, 873-85.
[6] Chew, C.S. et al. (2005) Am J Physiol Gastrointest Liver Physiol 288, G376-87.
[7] Jin, S.H. et al. (2008) Int J Cancer 122, 1040-6.
[8] Liu, Z. et al. (2010) Clin Cancer Res 16, 6009-18.
[9] Wang, S. et al. (2007) J Cell Sci 120, 567-77.
[10] Schmidt, V.A. et al. (2003) Blood 101, 3021-8.

IQGAP1 antibody Preparation Products And Raw materials

Raw materials

Preparation Products

IQGAP1 antibody Suppliers

Global( 49)Suppliers
Supplier Tel Email Country ProdList Advantage
Novus Biologicals 400821347 orders@novusbio.com China 6434 58
GeneTex, Inc. 0755-26755892 1-949-553-1900 international@genetex.com China 6092 58
NSJ Bioreagents 858.663.9055 8586639055 NSJBioname@qq.com China 6941 58
Enzo Biochem Inc Enzo Biochem Inc. 13797054060 Enzoname@qq.com China 6174 58
Cell Signaling Technology Inc 21-80243558 86218024 info@cellsignal.cn China 6427 58
Abmart Inc 4006-123-828 13162017139 market@ab-mart.com China 6917 58
Wuhan Fine Biotech Co Ltd 13047170542 marketing@fn-test.com China 6600 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 sales@biosynth.com China 6051 58
Rockland Immunochemicals Inc 0512-65829739 antibodies-onlinename@qq.com China 6808 58
Shanghai Tuoran Biotechnology Co., Ltd. 18621916228 CHINA 5067 58
IQGAP1 antibody
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