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CTR9 (D1Z4F) Rabbit mAb

CAS No.
Chemical Name:
CTR9 (D1Z4F) Rabbit mAb
Synonyms
CTR9 (D1Z4F) Rabbit mAb
CBNumber:
CB85726486
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

CTR9 (D1Z4F) Rabbit mAb Chemical Properties,Uses,Production

Source

Rabbit

Reactivity

Human;Mouse;Rat

Background

The PAF associated factor) complex was initially identified in yeast and is comprised of subunits PAF1, Leo1, Ctr9, Cdc73, RTF1 and Ski8. The PAF complex plays an important role in transcription initiation and elongation by RNAPII by regulating the establishment of proper histone modifications such as histone H2B ubiquitination and the recruitment of the histone chaperone FACT. The PAF complex also plays a role in mRNA processing and maturation by interacting with and recruiting the cleavage and polyadenylation specificity factor and cleavage stimulation factor complexes via the Cdc73 subunit. In addition, the Ski8 subunit of the PAF complex is part of the hSKi complex that regulates RNA surveillance, suggesting an important function of the complex in coordinating events associated with proper RNA maturation during transcription.

References

[1] Jaehning, J.A. (2010) Biochim Biophys Acta 1799, 379-88.
[2] Chaudhary, K. et al. (2007) Oncogene 26, 7499-507.
[3] Pavri, R. et al. (2006) Cell 125, 703-17.
[4] Rozenblatt-Rosen, O. et al. (2005) Mol Cell Biol 25, 612-20.
[5] Zhu, B. et al. (2005) Genes Dev 19, 1668-1673.
[6] Rozenblatt-Rosen, O. et al. (2009) Proc Natl Acad Sci U S A 106, 755-60.
[7] Farber, L.J. et al. (2010) Mol Carcinog 49, 215-223.

CTR9 (D1Z4F) Rabbit mAb Preparation Products And Raw materials

Raw materials

Preparation Products

CTR9 (D1Z4F) Rabbit mAb Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Cell Signaling Technology Inc 21-80243558 86218024 info@cellsignal.cn China 6427 58
Guangzhou Jinling Biotechnology Co., Ltd. 15017560539 CHINA 6140 58
Hangzhou Novas Biotechnology Co., Ltd. 15264006066 CHINA 1844 58
Guangzhou Keda Heng New Technology Co., Ltd. 17328662120 CHINA 6139 58
Shanghai Tuoran Biotechnology Co., Ltd. 18621916228 CHINA 5067 58
CTR9 (D1Z4F) Rabbit mAb
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