ChemicalBook >> CAS DataBase List >>Mc-Val-Cit-PAB-Cl
Mc-Val-Cit-PAB-Cl
- CAS No.
- 1639351-92-0
- Chemical Name:
- Mc-Val-Cit-PAB-Cl
- Synonyms
- Mc-Val-Cit-PAB-Cl;Mc Val Cit PAB Cl,Antibody-drug conjugates linkers,McValCitPABCl,ADC Linkers,inhibit,Inhibitor;L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(chloromethyl)phenyl]-;N-[(S)-1-[[(S)-1-[[4-(Chloromethyl)phenyl]amino]-1-oxo-5-ureido-2-pentyl]amino]-3-methyl-1-oxo-2-butyl]-6-(2,5-dioxo-2,5-dihydro-1-pyrrolyl)hexanamide;N-[(1S)-1-{[(1S)-4-(carbamoylamino)-1-{[4-(chloromethyl)phenyl]carbamoyl}butyl]carbamoyl}-2-methylpropyl]-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide;N-((S)-1-(((S)-1-((4-(Chloromethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide
- CBNumber:
- CB85821132
- Molecular Formula:
- C28H39ClN6O6
- Molecular Weight:
- 591.1
- MDL Number:
- MFCD32201033
- MOL File:
- 1639351-92-0.mol
- MSDS File:
- SDS
Last updated:2026-07-18 07:23:31
| Product description | Number | Pack Size | Price |
| Mc-Val-Cit-PAB-Cl ≥95% | CS-0043347 | 25mg | $183 |
| Mc-Val-Cit-PAB-Cl ≥95% | CS-0043347 | 100mg | $487 |
| Mc-Val-Cit-PAB-Cl ≥95% | CS-0043347 | 25mg | $183 |
| Mc-Val-Cit-PAB-Cl ≥95% | CS-0043347 | 100mg | $487 |
| N-((S)-1-(((S)-1-((4-(Chloromethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide | 297910 | 10.00mg | $104 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317 |
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P362+P364 |
Mc-Val-Cit-PAB-Cl price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0043347 | Mc-Val-Cit-PAB-Cl ≥95% | 1639351-92-0 | 25mg | $183 | 2026-06-04 | Buy |
| ChemScene | CS-0043347 | Mc-Val-Cit-PAB-Cl ≥95% | 1639351-92-0 | 100mg | $487 | 2026-06-04 | Buy |
| ChemScene | CS-0043347 | Mc-Val-Cit-PAB-Cl ≥95% | 1639351-92-0 | 25mg | $183 | 2026-06-04 | Buy |
| ChemScene | CS-0043347 | Mc-Val-Cit-PAB-Cl ≥95% | 1639351-92-0 | 100mg | $487 | 2026-06-04 | Buy |
| Matrix Scientific | 297910 | N-((S)-1-(((S)-1-((4-(Chloromethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide | 1639351-92-0 | 10.00mg | $104 | 2026-05-19 | Buy |
Mc-Val-Cit-PAB-Cl Chemical Properties,Uses,Production
Uses
Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).
IC 50
Protease Cleavable Linker; Cleavable Linker
References
[1] Staben LR, et al. Stabilizing a Tubulysin Antibody-Drug Conjugate To Enable Activity Against Multidrug-Resistant Tumors. ACS Med Chem Lett. 2017 Sep 5;8(10):1037-1041. DOI:10.1021/acsmedchemlett.7b00243
Mc-Val-Cit-PAB-Cl Preparation Products And Raw materials
Raw materials
Preparation Products
Mc-Val-Cit-PAB-Cl Suppliers
Global( 44)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32468 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +86-0086-13720134139 | orders@jknbiochem.com | China | 5221 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 | 3525679403@qq.com | China | 4332 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4876 | 55 | |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Wellman Pharmaceutical Group Limited | 15807197853 18971451745 | 15807197853@163.com | China | 3672 | 58 |
View Lastest Price from Mc-Val-Cit-PAB-Cl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-17 | Mc-Val-Cit-PAB-Cl
1639351-92-0
|
$97.00-395.00 | 99.79% | 10g | TargetMol Chemicals Inc. |
-
- Mc-Val-Cit-PAB-Cl
1639351-92-0
- $97.00-395.00
- 99.79%
- TargetMol Chemicals Inc.
Mc-Val-Cit-PAB-Cl
L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(chloromethyl)phenyl]-
Mc Val Cit PAB Cl,Antibody-drug conjugates linkers,McValCitPABCl,ADC Linkers,inhibit,Inhibitor
N-[(S)-1-[[(S)-1-[[4-(Chloromethyl)phenyl]amino]-1-oxo-5-ureido-2-pentyl]amino]-3-methyl-1-oxo-2-butyl]-6-(2,5-dioxo-2,5-dihydro-1-pyrrolyl)hexanamide
N-[(1S)-1-{[(1S)-4-(carbamoylamino)-1-{[4-(chloromethyl)phenyl]carbamoyl}butyl]carbamoyl}-2-methylpropyl]-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide
N-((S)-1-(((S)-1-((4-(Chloromethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide
1639351-92-0
C28H39ClN6O6
