3,5-Bis(trifluoromethyl)benzyl bromide
- CAS No.
- 32247-96-4
- Chemical Name:
- 3,5-Bis(trifluoromethyl)benzyl bromide
- Synonyms
- 1-(BROMOMETHYL)-3,5-BIS(TRIFLUOROMETHYL)BENZENE;5-Bis(trifluoroMethyl)benzyl broMide;3,5-Bis(trifluoremethyl)benzylbromide;3,5-BIS(TRIFLUOROMETHYL)BENZYL BROMIDE;3,5-DI(TRIFLUORO METHYL)BENZYL BROMIDE;3,5-Bis(trifluoromethyl)benzylbromiode;3,5-Bis(trifluoromethyl)benzylbromide98%;3,5-Bis(trifluoromethyl)benzyl bromide 98%;3,5-Bis(trifluoromethyl)benzyl Bromide >3,5-Bis(trifluoromethyl)benzyl bromide, 97+%
- CBNumber:
- CB8709789
- Molecular Formula:
- C9H5BrF6
- Molecular Weight:
- 307.03
- MDL Number:
- MFCD00009905
- MOL File:
- 32247-96-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3,5-Bis(trifluoromethyl)benzyl bromide 97% | 263397 | 1g | $29.1 |
| 3,5-Bis(trifluoromethyl)benzyl bromide 97% | 263397 | 5g | $69.1 |
| 3,5-Bis(trifluoromethyl)benzyl Bromide >96.0%(GC) | B1867 | 5g | $47 |
| 3,5-Bis(trifluoromethyl)benzyl Bromide >96.0%(GC) | B1867 | 25g | $187 |
| 3,5-Bis(trifluoromethyl)benzyl Bromide | TRC-B585575-5G | 5g | $154 |
| More product size | |||
| Melting point | 18°C |
|---|---|
| Boiling point | 136-140°C 14mm |
| Density | 1.675 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 79 °F |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Difficult to mix. |
| form | Liquid |
| color | Clear colorless to yellow-brown |
| Specific Gravity | 1.675 |
| Sensitive | Lachrymatory |
| BRN | 656506 |
| InChI | InChI=1S/C9H5BrF6/c10-4-5-1-6(8(11,12)13)3-7(2-5)9(14,15)16/h1-3H,4H2 |
| InChIKey | ATLQGZVLWOURFU-UHFFFAOYSA-N |
| SMILES | C1(CBr)=CC(C(F)(F)F)=CC(C(F)(F)F)=C1 |
| CAS DataBase Reference | 32247-96-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 3,5-Bis(trifluoromethyl)benzyl bromide(32247-96-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H314 | |||||||||
| Precautionary statements | P210-P233-P240-P280-P303+P361+P353-P305+P351+P338 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C,F | |||||||||
| Risk Statements | 10-34 | |||||||||
| Safety Statements | 26-36/37/39-45-25-16 | |||||||||
| RIDADR | UN 2920 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Corrosive/Lachrymatory | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29039990 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Eye Dam. 1 Flam. Liq. 3 Skin Corr. 1B |
|||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
3,5-Bis(trifluoromethyl)benzyl bromide price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 263397 | 3,5-Bis(trifluoromethyl)benzyl bromide 97% | 32247-96-4 | 1g | $29.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 263397 | 3,5-Bis(trifluoromethyl)benzyl bromide 97% | 32247-96-4 | 5g | $69.1 | 2026-04-30 | Buy |
| TCI Chemical | B1867 | 3,5-Bis(trifluoromethyl)benzyl Bromide >96.0%(GC) | 32247-96-4 | 5g | $47 | 2026-04-30 | Buy |
| TCI Chemical | B1867 | 3,5-Bis(trifluoromethyl)benzyl Bromide >96.0%(GC) | 32247-96-4 | 25g | $187 | 2026-04-30 | Buy |
| TRC | TRC-B585575-5G | 3,5-Bis(trifluoromethyl)benzyl Bromide | 32247-96-4 | 5g | $154 | 2026-06-03 | Buy |
3,5-Bis(trifluoromethyl)benzyl bromide Chemical Properties,Uses,Production
Chemical Properties
White or Colorles to Yellow to Orange powder to lump to clear liquid
Uses
3,5-Bis(trifluoromethyl)benzyl bromide is used as derivatization reagent in detection of uracil in DNA by GC and negative chemical ionization mass spectrometry in enantioselective synthesis of non-peptidic neurokinin NK1 receptor antagonist.
Synthesis
Synthesis of 3, 5-bis (trifluoromethyl)-benzyl bromide:
In a 4-neck flask with capacity 1000 ml equipped with mechanical agitator, thermometer, bubble condenser and 100 ml loading funnel, 262.2 g of the product of Example 1 (ii) at 92. 8% (0. 988 moles), 550,2 g HBr 48% (3.2645 moles) are loaded; this is heated at 50°C so as to melt the alcohol, then one starts to dose 113 g of concentrated His04 (1.153 moles). Pouring is accomplished in 30 minutes, noting an increase of the internal temperature. This is heated to 100-105°C and left to react for 8 hours. The reaction is completed by reflux heating for per 1.5 hours. the mixture is left to settle and the phases are separated; the solvents are removed from the organic phase and the product in the title is obtained with a yield of 99.1 %.
References
[1] Patent: WO2005/35472, 2005, A1. Location in patent: Page/Page column 7-8
[2] Advanced Synthesis and Catalysis, 2016, vol. 358, # 11, p. 1731 - 1735
3,5-Bis(trifluoromethyl)benzyl bromide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Sunsoly S&T Co.,Ltd | +86-13910445483; +8613910445483 | amanda@sunsoly.com | China | 300 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20120 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from 3,5-Bis(trifluoromethyl)benzyl bromide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-09 | 3,5-Bis(trifluoromethyl)benzyl bromide
32247-96-4
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-04-04 | 3,5-Bis(trifluoromethyl)benzyl bromide
32247-96-4
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2019-09-02 | 3,5-Bis(trifluoromethyl)benzyl bromide
32247-96-4
|
$7.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 3,5-Bis(trifluoromethyl)benzyl bromide
32247-96-4
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3,5-Bis(trifluoromethyl)benzyl bromide
32247-96-4
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 3,5-Bis(trifluoromethyl)benzyl bromide
32247-96-4
- $7.00
- 99%
- Career Henan Chemical Co
32247-96-4(3,5-Bis(trifluoromethyl)benzyl bromide)Related Search:
1of4
