L(+)-Homoarginine hydrochloride
- CAS No.
- 1483-01-8
- Chemical Name:
- L(+)-Homoarginine hydrochloride
- Synonyms
- L-HOMOARGININE HYDROCHLORIDE;NSC 145416;HomoArg.HCl;H-HAR-OH HCL;-(+)-Homoarg;H-HArg-OH·HCl;L-Homoarg.hcl;inine hydrochL;H-L-HArg-OH*HCl;H-HOMOARG-OH HCL
- CBNumber:
- CB8732118
- Molecular Formula:
- C7H17ClN4O2
- Molecular Weight:
- 224.69
- MDL Number:
- MFCD00012622
- MOL File:
- 1483-01-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| L-Homoarginine hydrochloride unnatural arginine analog | H1007 | 5g | $399 |
| L-Homoarginine Hydrochloride >97.0%(T) | H1172 | 1g | $83 |
| L-Homoarginine Hydrochloride >97.0%(T) | H1172 | 5g | $243 |
| L-Homoarginine (hydrochloride) ≥95% | 22285 | 1g | $49 |
| L-Homoarginine (hydrochloride) ≥95% | 22285 | 5g | $202 |
| More product size | |||
| Melting point | 213-215 °C(lit.) |
|---|---|
| alpha | 18 º (c=1, 1N HCl) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: 50 mg/mL, clear to slightly hazy, faintly yellow |
| form | Granular Powder |
| color | White |
| Water Solubility | Soluble in water(50 mg/mL). |
| BRN | 4016621 |
| Stability | Moisture Sensitive |
| Major Application | peptide synthesis |
| InChI | InChI=1/C7H16N4O2.ClH/c8-5(6(12)13)3-1-2-4-11-7(9)10;/h5H,1-4,8H2,(H,12,13)(H4,9,10,11);1H/t5-;/s3 |
| InChIKey | YMKBVNVCKUYUDM-USHJBNIQNA-N |
| SMILES | C(CCCNC(=N)N)[C@H](N)C(=O)O.Cl |&1:8,r| |
| CAS DataBase Reference | 1483-01-8(CAS DataBase Reference) |
| UNSPSC Code | 12352209 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-36/37/39-27-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29252900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
L(+)-Homoarginine hydrochloride price More Price(94)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H1007 | L-Homoarginine hydrochloride unnatural arginine analog | 1483-01-8 | 5g | $399 | 2026-04-30 | Buy |
| TCI Chemical | H1172 | L-Homoarginine Hydrochloride >97.0%(T) | 1483-01-8 | 1g | $83 | 2026-04-30 | Buy |
| TCI Chemical | H1172 | L-Homoarginine Hydrochloride >97.0%(T) | 1483-01-8 | 5g | $243 | 2026-04-30 | Buy |
| Cayman Chemical | 22285 | L-Homoarginine (hydrochloride) ≥95% | 1483-01-8 | 1g | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 22285 | L-Homoarginine (hydrochloride) ≥95% | 1483-01-8 | 5g | $202 | 2026-04-30 | Buy |
L(+)-Homoarginine hydrochloride Chemical Properties,Uses,Production
Description
L-Homoarginine is an uncompetitive and organ-specific inhibitor of alkaline phosphatases. This non-essential amino acid inhibits human bone and liver alkaline phosphatases but has no effect on placental or intestinal isoenzymes. In vitro, L-homoarginine inhibits [3H]thymidine uptake by mouse myeloma MOPC 104E cells and inhibits proliferation of C3H/He mouse osteosarcoma cells. Pre-treatment with L-homoarginine delays in vivo tumor growth in a murine C3H/He osteosarcoma model. It also inhibits high-protein diet-induced pancreatic growth and enzyme secretion in bile-pancreatic juice-diverted rats, a model for the induction of pancreatic enzyme secretion with hypercholecystokininemia.
Chemical Properties
White Powder
Uses
An inhibitor of alkaline phosphatase isoenzymes. It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter. The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.
Uses
An inhibitor of alkaline phosphatase isoenzymes. An analog of Homoarginine (H585000).
Biochem/physiol Actions
Homoarginine is an inhibitor of tissue nonspecific alkaline phosphatase (TNALP). It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter.
IC 50
Human Endogenous Metabolite
References
[1] CHI-WEI LIN W F. L-Homoarginine. An organ-specific, uncompetitive inhibitor of human liver and bone alkaline phosphohydrolases.[J]. The Journal of Biological Chemistry, 1972, 16 1: 3082-3087. DOI: 10.1016/s0021-9258(19)45215-0
[2] Y KIKUCHI K K I Kizawa. [Inhibitory effect of L-homoarginine on murine osteosarcoma cell proliferation].[J]. Japanese Journal of Cancer and Chemotherapy, 1982, 9 5: 888-897.
[3] T. HIRA H. H S Ohyama. l-Homoarginine suppresses exocrine pancreas in rats[J]. Amino Acids, 2003, 24 4: 389-396. DOI: 10.1007/s00726-002-0344-2
L(+)-Homoarginine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +8617392709771 | 1097@dideu.com | China | 3993 | 58 |
| Sichuan HongRi Pharma-Tech Co.,Ltd | +8618382028708 | ni@enlaibio.com | China | 1103 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Shanghai Worldyang Chemical Co.,Ltd. | +86-021-56795779 +8613651600618 | sales@worldyachem.com | China | 967 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6366 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
View Lastest Price from L(+)-Homoarginine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | L-Homoarg.hcl
1483-01-8
|
1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
 |
2026-07-24 | L(+)-Homoarginine hydrochloride
1483-01-8
|
1KG | 98.0% | 5000kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-07-24 | L-Homoarginine Hydrochloride
1483-01-8
|
50g | 98.0%-101.5% | 100kg | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- L-Homoarg.hcl
1483-01-8
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- L(+)-Homoarginine hydrochloride
1483-01-8
- $0.00
- 98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- L-Homoarginine Hydrochloride
1483-01-8
- 98.0%-101.5%
- WUHAN FORTUNA CHEMICAL CO., LTD
