Danofloxacin mesylate
- CAS No.
- 119478-55-6
- Chemical Name:
- Danofloxacin mesylate
- Synonyms
- Advoci;Nofloxacin;CP-76136-27;Dafloxacin mesylate;Danofloxacin Mesylat;DANOFLOXACIN MESYLATE;DANOFLOXACIN MESULATE;DANOFLOXACIN MESILATE;Mesylate Danofloxacin;DANOFLOXANCIN MESYLATE
- CBNumber:
- CB8736590
- Molecular Formula:
- C19H20FN3O3.CH4O3S
- Molecular Weight:
- 453.49
- MDL Number:
- MFCD00673687
- MOL File:
- 119478-55-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Danofloxacin (mesylate) ≥98% | 22408 | 50mg | $49 |
| Danofloxacin (mesylate) ≥98% | 22408 | 100mg | $82 |
| Danofloxacin (mesylate) ≥98% | 22408 | 250mg | $190 |
| Danofloxacin (mesylate) ≥98% | 22408 | 1g | $516 |
| Danofloxacin Mesylate (Danofloxacin Methanesulfonate, CP-76136-27, Advocin) | D1038-50 | 10mg | $340 |
| More product size | |||
| Melting point | 337-339°C |
|---|---|
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Aqueous Base (Slightly, Sonicated), DMSO (Slightly, Sonicated) |
| form | Solid |
| color | White to Off-White |
| Stability | Hygroscopic |
| InChIKey | APFDJSVKQNSTKF-LWBBREITNA-N |
| SMILES | C12C=C(C(F)=CC=1C(C(C(=O)O)=CN2C1CC1)=O)N1C[C@@]2([H])N(C)C[C@]1([H])C2.S(=O)(=O)(O)C |&1:20,25,r| |
| CAS DataBase Reference | 119478-55-6(CAS DataBase Reference) |
| FDA UNII | 94F3SX3LEM |
| UNSPSC Code | 51101500 |
| NACRES | NA.41 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H412-H373 |
| Precautionary statements | P273-P501-P260-P314-P501 |
| Safety Statements | 24/25 |
| WGK Germany | WGK 2 |
| HS Code | 29339900 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Aquatic Chronic 3 STOT RE 2 |
Danofloxacin mesylate price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22408 | Danofloxacin (mesylate) ≥98% | 119478-55-6 | 50mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 22408 | Danofloxacin (mesylate) ≥98% | 119478-55-6 | 100mg | $82 | 2026-04-30 | Buy |
| Cayman Chemical | 22408 | Danofloxacin (mesylate) ≥98% | 119478-55-6 | 250mg | $190 | 2026-04-30 | Buy |
| Cayman Chemical | 22408 | Danofloxacin (mesylate) ≥98% | 119478-55-6 | 1g | $516 | 2026-04-30 | Buy |
| Usbiological | D1038-50 | Danofloxacin Mesylate (Danofloxacin Methanesulfonate, CP-76136-27, Advocin) | 119478-55-6 | 10mg | $340 | 2026-06-03 | Buy |
Danofloxacin mesylate Chemical Properties,Uses,Production
Description
Danofloxacin is a fluoroquinolone antibiotic and a type II topoisomerase inhibitor. It has a broad antimicrobial spectrum. It can be used as an anti-infective agent for veterinary use only.
Brand Name(s) in US
Advocin
Reference
J. A. Schrickx, J. Fink-Gremmels, Danofloxacin-mesylate is a substrate for ATP-dependent efflux transporters, British Journal of Pharmacology, 2009, vol. 150, pp. 463-469
Description
Danofloxacin is a fluoroquinolone antibiotic. In vitro, danofloxacin has activity against 68 field isolates of Mycoplasma species isolated from cattle, swine, and poultry with MICs ranging from 8 to 500 nM. It is protective in vivo against P. multocida, E. coli, and S. choleraesuis in mice with protective doses of 0.31, 0.40, and 2.42 mg/kg, respectively. Formulations containing danofloxacin are widely used to prevent infectious disease in livestock.
Chemical Properties
Crystalline Solid
Uses
Fluorinated quinolone antibacterial.
Uses
Danofloxacin is a fluoroquinolone antibacterial for veterinary use, with MIC90 of 0.28 μM
Definition
ChEBI: Danofloxacin mesylate is a member of quinolines.
Veterinary Drugs and Treatments
Danofloxacin mesylate injection is indicated for the treatment of
Bovine Respiratory Disease (BRD) associated with Mannheimia
(Pasturella) hemolytica and P. multocida in cattle (not dairy or
veal). Because of the drug’s spectrum of activity, it may also be of
benefit in the treatment of infections caused by Histophilus somni
(Haemophilus somnus) or M. bovis, but the drug is not labeled (at
the time of writing) for treating these pathogens. In other countries,
danofloxacin may be labeled for use in swine and chickens
(non-laying), but in the USA it is illegal to use the drug in an extralabel
manner in food-producing species.
Danofloxacin may be of benefit in treating susceptible infections in
adult horses, camelids and other non-food producing species.
References
[1] A.C. COOPER. In vitro activity of danofloxacin, tylosin and oxytetracycline against mycoplasmas of veterinary importance[J]. Research in veterinary science, 1993, 54 3: Pages 329-334. DOI: 10.1016/0034-5288(93)90130-8
[2] PAUL R. MCGUIRK. Synthesis and structure-activity relationships of 7-diazabicycloalkylquinolones, including danofloxacin, a new quinolone antibacterial agent for veterinary medicine[J]. Journal of Medicinal Chemistry, 1992, 35 4: 611-620. DOI: 10.1021/jm00082a001
[3] MIN YAO. The regulation effects of danofloxacin on pig immune stress induced by LPS[J]. Research in veterinary science, 2017, 110: Pages 65-71. DOI: 10.1016/j.rvsc.2016.11.005
Danofloxacin mesylate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8737 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-17392712779 | 1097@dideu.com | China | 3989 | 58 |
| shandong perfect biotechnology co.ltd | +86-53169958659 +86-13153181156 | sales@sdperfect.com | China | 293 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | sarah@tnjone.com | China | 1139 | 58 | |
| Henan Suikang Pharmaceutical Co.,Ltd. | +86-18239973690 | sales@suikangpharm.com | China | 311 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21531 | 55 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Hubei Ipure Biology Co., Ltd | +8618062405514 | ada@ipurechemical.com | China | 10224 | 58 |
View Lastest Price from Danofloxacin mesylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-08 | Danofloxacin mesylate
119478-55-6
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-08-07 | Danofloxacin mesylate
119478-55-6
|
1KG | 99% | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-08-03 | Danofloxacin mesylate
119478-55-6
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd |
-
- Danofloxacin mesylate
119478-55-6
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Danofloxacin mesylate
119478-55-6
- $0.00
- 99%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Danofloxacin mesylate
119478-55-6
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
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