10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE
![10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE Structure](CAS/GIF/160588-45-4.gif)
- CAS No.
- 160588-45-4
- Chemical Name:
- 10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE
- Synonyms
- XR 543;DMP 543;DMP 543,DMP543;DMP 543 (XR-543;DMP-543, 10 mM in DMSO;10,10-BIS[(2-FLUORO-4-PYRIDYL)METHYL]ANTHRONE;10,10-Bis((2-fluoropyridin-4-yl)Methyl)anthracen-9(10H)-one;10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE;9(10H)-Anthracenone, 10,10-bis[(2-fluoro-4-pyridinyl)methyl]-;10,10-bis[(2-fluoropyridin-4-yl)methyl]-9,10-dihydroanthracen-9-one
- CBNumber:
- CB8843647
- Molecular Formula:
- C26H18F2N2O
- Molecular Weight:
- 412.43
- MDL Number:
- MFCD00934500
- MOL File:
- 160588-45-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| DMP 543 ≥98% | 32849 | 1mg | $36 |
| DMP 543 ≥98% | 32849 | 5mg | $120 |
| DMP 543 ≥98% | 32849 | 10mg | $169 |
| DMP 543 ≥99% | 255174 | 10mg | $423 |
| DMP 543 ≥99% | 255174 | 50mg | $1103 |
| Melting point | 159-161 °C |
|---|---|
| Boiling point | 593.1±50.0 °C(Predicted) |
| Density | 1.319±0.06 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| form | Powder |
| pka | 0.38±0.10(Predicted) |
| color | White to yellow |
| FDA UNII | DYD4418J7V |
10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 32849 | DMP 543 ≥98% | 160588-45-4 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 32849 | DMP 543 ≥98% | 160588-45-4 | 5mg | $120 | 2026-04-30 | Buy |
| Cayman Chemical | 32849 | DMP 543 ≥98% | 160588-45-4 | 10mg | $169 | 2026-04-30 | Buy |
| Usbiological | 255174 | DMP 543 ≥99% | 160588-45-4 | 10mg | $423 | 2026-06-03 | Buy |
| Usbiological | 255174 | DMP 543 ≥99% | 160588-45-4 | 50mg | $1103 | 2026-06-03 | Buy |
10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE Chemical Properties,Uses,Production
Uses
DMP-543 (XR-543) is a KV7 channel blocker, also acts as a potent neurotransmitter release enhancer[1][2].
Definition
ChEBI: 10,10-bis[(2-fluoro-4-pyridinyl)methyl]-9-anthracenone is a member of anthracenes.
References
[1] Ipavec V, et al. KV7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fundus. Pharmacol Res. 2011 Oct;64(4):397-409. DOI:10.1016/j.phrs.2011.06.016
[2] Zaczek R, et al. Two new potent neurotransmitter release enhancers, 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone and 10,10-bis(2-fluoro-4-pyridinylmethyl)-9(10H)-anthracenone: comparison to linopirdine. J Pharmacol Exp Ther. 1998 May;285(2):724-30. PMID:9580619
10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE Preparation Products And Raw materials
Raw materials
Preparation Products
10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4865 | 55 | |
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2826 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9804 | 58 |
