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ChemicalBook >> CAS DataBase List >>cycrimine

cycrimine

CAS No.
77-39-4
Chemical Name:
cycrimine
Synonyms
cycrimine;cycrimine USP/EP/BP;1-Piperidinepropanol, α-cyclopentyl-α-phenyl-;1-Piperidinepropanol, a-cyclopentyl-a-phenyl-;α-Cyclopentyl-α-phenyl-1-piperidine-1-propanol;1-Phenyl-1-cyclopentyl-3-piperidino-1-propanol;1-cyclopentyl-1-phenyl-3-piperidino-propan-1-ol;1-cyclopentyl-1-phenyl-3-piperidin-1-ylpropan-1-ol;1-cyclopentyl-1-phenyl-3-piperidin-1-yl-propan-1-ol
CBNumber:
CB8937186
Molecular Formula:
C19H29NO
Molecular Weight:
287.444
MDL Number:
MFCD00865230
MOL File:
77-39-4.mol
MSDS File:
SDS
Last updated:2026-07-16 07:06:08
Product description Number Pack Size Price
Cycrimine ≥98% 445395 100mg $475
Cycrimine ≥98% 445395 250mg $998
Cycrimine 99.85% CS-0078367 1mg $173
Cycrimine 99.85% CS-0078367 5mg $412
Cycrimine 99.85% CS-0078367 10mg $650

cycrimine Properties

Melting point 90-92°C
Boiling point 125-135 °C(Press: 0.02 Torr)
Density 1.057±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Ethyl Acetate, Methanol (Slightly)
form Solid
pka 14.40±0.29(Predicted)
color Off-White to Pale Yellow
Stability Stable under recommended storage conditions., Stable Under Recommended Storage C
FDA UNII 543567RFQQ

cycrimine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 445395 Cycrimine ≥98% 77-39-4 100mg $475 2026-06-03 Buy
Usbiological 445395 Cycrimine ≥98% 77-39-4 250mg $998 2026-06-03 Buy
ChemScene CS-0078367 Cycrimine 99.85% 77-39-4 1mg $173 2026-06-04 Buy
ChemScene CS-0078367 Cycrimine 99.85% 77-39-4 5mg $412 2026-06-04 Buy
ChemScene CS-0078367 Cycrimine 99.85% 77-39-4 10mg $650 2026-06-04 Buy
Product number Packaging Price Buy
445395 100mg $475 Buy
445395 250mg $998 Buy
CS-0078367 1mg $173 Buy
CS-0078367 5mg $412 Buy
CS-0078367 10mg $650 Buy

cycrimine Chemical Properties,Uses,Production

Originator

Pagitane,Lilly,US,1953

Uses

Cycrimine is a cholinolytic anti-Parkinson drug which can cause neuromuscular blockades in isolated rat diaphragms.

Definition

ChEBI: A member of the class of piperidines that is 3-(piperidin-1-yl)propan-1-ol in which one of the hydrogen atoms at the 1-position is substituted by cyclopentyl, and the other is substituted by phenyl. A central anticholinergic, it is used as its hydrochlorid salt in the management and treatment of Parkinson's disease.

Manufacturing Process

The manufacture of the cyclohexyl analog is as follows. Phenyl magnesium bromide was prepared from 48.5 g (0.308 mol) of bromobenzene, 7 g (0.29 mol) of magnesium, and 125 ml of dry ether. To it was added at 5°C over a period of hour 40 g (0.18 mol) of cyclohexyl β-(N-piperidyl)-ethyl ketone (BP 115° to 117°C/1 mm) in 125 ml of dry ether. The mixture was allowed slowly to come to room temperature, refluxed for one hour, and then poured into ice containing 80 ml of concentrated hydrochloric acid. Ammonium chloride (100 g) and 200 ml of concentrated ammonium hydroxide were added and the organic layer was separated. After drying and removing the solvent, the residue was distilled under reduced pressure. The base distilled at 158° to 170°C (1 mm) and solidified. Upon recrystallization from methanol it melted at 112° to 113°C.

brand name

Pagitane (Lilly).

Therapeutic Function

Muscle relaxant, Antiparkinsonian

cycrimine Preparation Products And Raw materials

Raw materials

Preparation Products

cycrimine Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1059@dideu.com China 29120 58
TargetMol Chemicals Inc.
13564774135 marketing@targetmol.com United States 19956 58
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12335 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1248 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11972 58
Baoji Didu Pharmaceutical and Chemical Co., Ltd 029-81145305 17791533577 1021@dideu.com China 9997 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29879 58
Chengdu Peter-like Biotechnology Co., Ltd. 028-81700200 13308200041 2851167782@qq.com China 10763 58
LGC Science (Shanghai) Ltd. 17717235263 offer.de@lgcgroup.com China 38235 58

View Lastest Price from cycrimine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cycrimine pictures 2026-07-15 Cycrimine
77-39-4
$985.00-1940.00 10g TargetMol Chemicals Inc.
cycrimine USP/EP/BP pictures 2025-11-18 cycrimine USP/EP/BP
77-39-4
$1.10 1g 99.9% 100 Tons min Dideu Industries Group Limited
  • Cycrimine pictures
  • Cycrimine
    77-39-4
  • $985.00-1940.00
  • TargetMol Chemicals Inc.
1-cyclopentyl-1-phenyl-3-piperidin-1-ylpropan-1-ol 1-cyclopentyl-1-phenyl-3-piperidino-propan-1-ol 1-Piperidinepropanol, a-cyclopentyl-a-phenyl- cycrimine 1-Phenyl-1-cyclopentyl-3-piperidino-1-propanol α-Cyclopentyl-α-phenyl-1-piperidine-1-propanol 1-cyclopentyl-1-phenyl-3-piperidin-1-yl-propan-1-ol cycrimine USP/EP/BP 1-Piperidinepropanol, α-cyclopentyl-α-phenyl- 77-39-4
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