DL-THREONINE METHYL ESTER HYDROCHLORIDE
- CAS No.
- 62076-66-8
- Chemical Name:
- DL-THREONINE METHYL ESTER HYDROCHLORIDE
- Synonyms
- methyl 2-amino-3-hydroxybutanoate;Methyl 2-aMino-3-hydroxybutanoate hydrochloride;3-NO2-Tyr-OH;H-DL-Thr-OMe.HCl;DL-THREONINE METHYL ESTER HYDROCHLORIDE;Threonine,methyl ester, hydrochloride (1:1);DL-THREONINE METHYL ESTER HYDROCHLORIDE USP/EP/BP
- CBNumber:
- CB9101261
- Molecular Formula:
- C5H12ClNO3
- Molecular Weight:
- 169.61
- MDL Number:
- MFCD00070400
- MOL File:
- 62076-66-8.mol
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| DL-THREONINE METHYL ESTER HYDROCHLORIDE AldrichCPR | S765430 | 50mg | $28.6 |
| DL-Threonine methyl ester hydrochloride ≥97% | CS-W022797 | 100g | $195 |
| DL-Threonine methyl ester hydrochloride ≥97% | CS-W022797 | 500g | $678 |
| DL-Threonine methyl ester hydrochloride 95% | OR928456 | 5g | $21 |
| DL-Threonine methyl ester hydrochloride 95% | OR928456 | 25g | $54 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
| HS Code | 2922500090 |
DL-THREONINE METHYL ESTER HYDROCHLORIDE price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S765430 | DL-THREONINE METHYL ESTER HYDROCHLORIDE AldrichCPR | 62076-66-8 | 50mg | $28.6 | 2022-05-15 | Buy |
| ChemScene | CS-W022797 | DL-Threonine methyl ester hydrochloride ≥97% | 62076-66-8 | 100g | $195 | 2026-06-04 | Buy |
| ChemScene | CS-W022797 | DL-Threonine methyl ester hydrochloride ≥97% | 62076-66-8 | 500g | $678 | 2026-06-04 | Buy |
| Apolloscientific | OR928456 | DL-Threonine methyl ester hydrochloride 95% | 62076-66-8 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR928456 | DL-Threonine methyl ester hydrochloride 95% | 62076-66-8 | 25g | $54 | 2026-06-04 | Buy |
DL-THREONINE METHYL ESTER HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
Dl-threonine methyl ester HCl
Synthesis
67-56-1
28954-12-3
39994-75-7
The general procedure for the synthesis of L-threonine methyl ester hydrochloride from methanol and (2S,3S)-2-amino-3-hydroxybutanoic acid was as follows: a mixture of (2S,3S)-2-amino-3-hydroxybutanoic acid (5.4 g, 24.6 mmol) and 6N HCl (60 mL) was refluxed for 5 hours. After completion of the reaction, it was cooled to room temperature and the reaction mixture was extracted with ether (3 x 70 mL) to remove the benzoic acid. The aqueous phase was concentrated to dryness under reduced pressure and the residue was further dried under high vacuum overnight to give crude allo-L-threonine. Methanol (25 mL) was cooled to 0 °C and thionyl chloride (1.80 mL, 25.2 mmol) was added slowly and dropwise. Crude allo-L-threonine was added to the resulting HCl methanol solution and the reaction mixture was heated to reflux for 1 hour. After completion of the reaction, the solvent was removed under vacuum and another batch of HCl methanol solution prepared in the same manner was added and again heated to reflux for 1 hour. Finally, the solvent was removed in vacuum to give allo-L-threonine methyl ester hydrochloride (4.15 g, 98% overall yield in two steps) as a red solid. The product was confirmed by 1H NMR (300 MHz, CD3OD): δ1.27 (d, J=6.6 Hz, 3H), 4.03 (d, J=3.3 Hz, 1H), 4.27-4.33 (m, 1H); 13C NMR (75 MHz, CD3OD): δ17.13,58.17,65.11,167.62; MS ( ESI, positive): m/z 134 [M+H]+.
References
[1] Journal of Organic Chemistry, 2002, vol. 67, # 5, p. 1536 - 1547
[2] Helvetica Chimica Acta, 1957, vol. 40, p. 1531,1544
[3] Journal of Organic Chemistry, 1997, vol. 62, # 21, p. 7364 - 7375
[4] Journal of Organic Chemistry, 2003, vol. 68, # 26, p. 10046 - 10057
[5] Journal of the American Chemical Society, 2007, vol. 129, # 18, p. 6017 - 6021
DL-THREONINE METHYL ESTER HYDROCHLORIDE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dideu Industries Group Limited | +86-86-15536356810 +8617392712697 | 1022@dideu.com | China | 28760 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9539 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
View Lastest Price from DL-THREONINE METHYL ESTER HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-29 | DL-Thr-Ome.HCl
62076-66-8
|
1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd
|
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2020-01-09 | DL-THREONINE METHYL ESTER HYDROCHLORIDE
62076-66-8
|
$1.00 | 1g | ≥98% | Career Henan Chemical Co |
-
- DL-Thr-Ome.HCl
62076-66-8
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- DL-THREONINE METHYL ESTER HYDROCHLORIDE
62076-66-8
- $1.00
- ≥98%
- Career Henan Chemical Co
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