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ChemicalBook >> CAS DataBase List >>N-Boc-5-aminolevulinic acid

N-Boc-5-aminolevulinic acid

CAS No.
72072-06-1
Chemical Name:
N-Boc-5-aminolevulinic acid
Synonyms
N-Boc-5-aminolevulinic acid;5-(Boc-amino)-4-oxo-pentanoic acid;5-(Tert-butoxycarbonylamino)-4-oxopentanoic acid;Pentanoic acid,5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-;5-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)-4-oxopentanoic acid
CBNumber:
CB91562166
Molecular Formula:
C10H17NO5
Molecular Weight:
231.25
MDL Number:
MFCD02682635
MOL File:
72072-06-1.mol
MSDS File:
SDS
Last updated:2026-05-28 04:25:49
Product description Number Pack Size Price
5-((tert-Butoxycarbonyl)amino)-4-oxopentanoic acid 303852 100.00mg $58
5-((tert-Butoxycarbonyl)amino)-4-oxopentanoic acid 303852 250.00mg $91
5-((tert-Butoxycarbonyl)amino)-4-oxopentanoic acid 303852 1.00g $226
5-((tert-Butoxycarbonyl)amino)-4-oxopentanoic acid 95+% B53242 100mg $60
5-((tert-Butoxycarbonyl)amino)-4-oxopentanoic acid 95+% B53242 250mg $100
More product size

N-Boc-5-aminolevulinic acid Properties

Boiling point 401.5±25.0 °C(Predicted)
Density 1.169±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 4.61±0.17(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P305+P351+P338

N-Boc-5-aminolevulinic acid price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 303852 5-((tert-Butoxycarbonyl)amino)-4-oxopentanoic acid 72072-06-1 100.00mg $58 2026-05-19 Buy
Matrix Scientific 303852 5-((tert-Butoxycarbonyl)amino)-4-oxopentanoic acid 72072-06-1 250.00mg $91 2026-05-19 Buy
Matrix Scientific 303852 5-((tert-Butoxycarbonyl)amino)-4-oxopentanoic acid 72072-06-1 1.00g $226 2026-05-19 Buy
Synthonix B53242 5-((tert-Butoxycarbonyl)amino)-4-oxopentanoic acid 95+% 72072-06-1 100mg $60 2026-05-06 Buy
Synthonix B53242 5-((tert-Butoxycarbonyl)amino)-4-oxopentanoic acid 95+% 72072-06-1 250mg $100 2026-05-06 Buy
Product number Packaging Price Buy
303852 100.00mg $58 Buy
303852 250.00mg $91 Buy
303852 1.00g $226 Buy
B53242 100mg $60 Buy
B53242 250mg $100 Buy

N-Boc-5-aminolevulinic acid Chemical Properties,Uses,Production

Synthesis

Di-tert-butyl dicarbonate

24424-99-5

5-Aminolevulinic acid hydrochloride

5451-09-2

N-Boc-5-aminolevulinic acid

72072-06-1

A suspension was prepared from 5-aminolevulinic acid hydrochloride (2) (5.00 g, 29.8 mmol), NaHCO3 (15.04 g, 179.0 mmol) and di-tert-butyl dicarbonate (6.51 g, 29.8 mmol) in anhydrous methanol and the reaction was stirred at room temperature overnight. Upon completion of the reaction, the insoluble solids were removed by filtration followed by evaporation to remove the solvent. The oily residue obtained was dissolved in water and the pH of the aqueous phase was adjusted with 10% aqueous KHSO4 to 2. The mixture was extracted with ethyl acetate (EtOAc), the organic phase was washed with saturated saline, dried over anhydrous Na2SO4, filtered and concentrated. The oily residue was purified by silica gel column chromatography (eluent ratio CH2Cl2/MeOH = 10/1) to afford the target product 5-((tert-butoxycarbonyl)amino)-4-oxopentanoic acid (3) (6.24 g, 90% yield) as a white solid with a melting point of 72-74°C (literature value 74-77°C). The spectral data of product 3 were in agreement with literature reports.

References

[1] Arkivoc, 2014, vol. 2014, # 3, p. 228 - 238
[2] Journal of Medicinal Chemistry, 2008, vol. 51, # 23, p. 7356 - 7369
[3] Photochemistry and Photobiology, 2003, vol. 78, # 5, p. 481 - 486

N-Boc-5-aminolevulinic acid Preparation Products And Raw materials

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N-Boc-5-aminolevulinic acid 5-(Tert-butoxycarbonylamino)-4-oxopentanoic acid 5-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)-4-oxopentanoic acid Pentanoic acid,5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo- 5-(Boc-amino)-4-oxo-pentanoic acid 72072-06-1
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