3′,4′-(Methylenedioxy)propiophenone
- CAS No.
- 28281-49-4
- Chemical Name:
- 3′,4′-(Methylenedioxy)propiophenone
- Synonyms
- 3,4-(METHYLENEDIOXY)PROPIOPHENONE;NSC 29484;ai3-31258;5-Propanoyl-1,3-benzodioxole;1,3-BENZODIOXOLE-5-PROPANOYL;5-PROPIONYL-1,3-BENZODIOXOLE;3,4-5(Methylenedioxy)propiophenone;1-(1,3-benzodioxol-5-yl)-1-propanon;3',4'-(Methylenedioxy)propiophenone;1-(1,3-benzodioxol-5-yl)propan-1-one
- CBNumber:
- CB9205460
- Molecular Formula:
- C10H10O3
- Molecular Weight:
- 178.18
- MDL Number:
- MFCD00016652
- MOL File:
- 28281-49-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3,4-Methylenedioxypropiophenone ≥98% | 39438 | 10mg | $71 |
| 3,4-Methylenedioxypropiophenone ≥98% | 39438 | 50mg | $245 |
| 3,4-Methylenedioxy Propiophenone | TRC-M304050-5G | 5g | $78 |
| 3,4-Methylenedioxy Propiophenone | TRC-M304050-1G | 1g | $73 |
| 3,4-Methylenedioxypropiophenone ≥98% | CS-W017337 | 500mg | $28 |
| Melting point | 34-36°C |
|---|---|
| Boiling point | 165-168°C 20mm |
| Density | 1,21 g/cm3 |
| Flash point | 165-168°C/20mm |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Low-Melting Solid |
| color | Off-White to Light Brown |
| BRN | 165729 |
| InChI | InChI=1S/C10H10O3/c1-2-8(11)7-3-4-9-10(5-7)13-6-12-9/h3-5H,2,6H2,1H3 |
| InChIKey | RVBJGSPBFIUTTR-UHFFFAOYSA-N |
| SMILES | C(C1=CC=C2OCOC2=C1)(=O)CC |
| CAS DataBase Reference | 28281-49-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 79S7K6SNO8 |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335-H411 | |||||||||
| Precautionary statements | P233-P260-P261-P264-P270-P271-P273-P280-P301+P312-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P330-P332+P313-P337+P313-P340-P362-P391-P403-P403+P233-P405-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 33-22 | |||||||||
| Safety Statements | 26-37 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| RTECS | UC0440600 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 2 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
3′,4′-(Methylenedioxy)propiophenone price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 39438 | 3,4-Methylenedioxypropiophenone ≥98% | 28281-49-4 | 10mg | $71 | 2026-04-30 | Buy |
| Cayman Chemical | 39438 | 3,4-Methylenedioxypropiophenone ≥98% | 28281-49-4 | 50mg | $245 | 2026-04-30 | Buy |
| TRC | TRC-M304050-5G | 3,4-Methylenedioxy Propiophenone | 28281-49-4 | 5g | $78 | 2026-06-03 | Buy |
| TRC | TRC-M304050-1G | 3,4-Methylenedioxy Propiophenone | 28281-49-4 | 1g | $73 | 2026-06-03 | Buy |
| ChemScene | CS-W017337 | 3,4-Methylenedioxypropiophenone ≥98% | 28281-49-4 | 500mg | $28 | 2026-06-04 | Buy |
3′,4′-(Methylenedioxy)propiophenone Chemical Properties,Uses,Production
Description
3′,4′-(Methylenedioxy)propiophenone, also known as 3,4-(Methylenedioxy)phenyl-1-propanone (MDP1P), is a member of the benzodioxole family, which is a five-membered heterocyclic compound. This compound is a phenylpropanoid found in some plants of the genus Piper and is an isomer of 3,4-methylenedioxyphenyl-2-propanone (MDP2P).
Chemical Properties
Pale Orange Solid
Uses
Intermediate in the production of Isosafrole and Ethylone.
Definition
ChEBI: 3,4-Methylenedioxypropiophenone is a member of benzodioxoles.
Application
3′,4′-(Methylenedioxy)propiophenone is a synthetic compound with a fatty acid chain. It has been shown to have potent activity against leishmania and has been used as an intermediate in the synthesis of other drugs. 3′,4′-(Methylenedioxy)propiophenone can be synthesized by acylation reactions with chloride and acetylcholinesterase inhibition. This product also has molecular docking properties, which have been analyzed using computational methods, such as profiling and profile analysis.
Synthesis Reference(s)
Tetrahedron Letters, 23, p. 3085, 1982 DOI: 10.1016/S0040-4039(00)87539-5
3′,4′-(Methylenedioxy)propiophenone Preparation Products And Raw materials
3′,4′-(Methylenedioxy)propiophenone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Shandong Liteng Biotechnology Co. , Ltd. | +86-18663721413 +86-15552573001 | rosy@litengpharm.com | China | 3279 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177 | faithe@yan-xi.com | China | 5838 | 58 |
| Shanghai UCHEM Inc. | +86-18930848214 +86-021-56762820 | sales@myuchem.com | China | 8899 | 58 |
| Anhui Yiao New Material Technology Co., Ltd | +86-18033737140 +86-17354101231 | sales1@hbganmiao.com | China | 217 | 58 |
| Suzhou Sanyi Polymer Chemical Technology Co., Ltd. | +86-18151108777 | 15571922873@163.com | China | 99 | 58 |
| Xiamen Wonderful Bio Technology Co., Ltd. | +86-13043004613 | Sara@xmwonderfulbio.com | China | 265 | 58 |
| Shaanxi Franta Biotechnology Co., Ltd | +86-13082019107 | admin@flanderff.com | China | 234 | 58 |
| Apeloa production Co.,Limited | +86-19131931000 | admin@apcl.com.cn | China | 856 | 58 |
| Shanghai Likang New Materials Co., Limited | +86-16631818819 +86-17736933208 | 3684455296@qq.com | China | 9287 | 58 |
View Lastest Price from 3′,4′-(Methylenedioxy)propiophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-07 | 3,4-(methylenedioxy)propiophenone
28281-49-4
|
$24.00-268.00 | 5g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
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2026-08-07 | 3,4-(METHYLENEDIOXY)PROPIOPHENONE
28281-49-4
|
$1.00 | 1kg | 99% | 100kg | RongNa Biotechnology Co.,Ltd | |
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2026-07-26 | 3,4-Methylenedioxyphenyl ethyl ketone
28281-49-4
|
1gram | 99.9% | 20tons | Shanghai Longyu Biotechnology Co., Ltd. |
-

- 3,4-(methylenedioxy)propiophenone
28281-49-4
- $24.00-268.00
- 0.98
- Shanghai UCHEM Inc.
-

- 3,4-(METHYLENEDIOXY)PROPIOPHENONE
28281-49-4
- $1.00
- 99%
- RongNa Biotechnology Co.,Ltd
-

- 3,4-Methylenedioxyphenyl ethyl ketone
28281-49-4
- $0.00
- 99.9%
- Shanghai Longyu Biotechnology Co., Ltd.









