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ChemicalBook >> CAS DataBase List >>3′,4′-(Methylenedioxy)propiophenone

3′,4′-(Methylenedioxy)propiophenone

CAS No.
28281-49-4
Chemical Name:
3′,4′-(Methylenedioxy)propiophenone
Synonyms
3,4-(METHYLENEDIOXY)PROPIOPHENONE;NSC 29484;ai3-31258;5-Propanoyl-1,3-benzodioxole;1,3-BENZODIOXOLE-5-PROPANOYL;5-PROPIONYL-1,3-BENZODIOXOLE;3,4-5(Methylenedioxy)propiophenone;1-(1,3-benzodioxol-5-yl)-1-propanon;3',4'-(Methylenedioxy)propiophenone;1-(1,3-benzodioxol-5-yl)propan-1-one
CBNumber:
CB9205460
Molecular Formula:
C10H10O3
Molecular Weight:
178.18
MDL Number:
MFCD00016652
MOL File:
28281-49-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:52:59
Product description Number Pack Size Price
3,4-Methylenedioxypropiophenone ≥98% 39438 10mg $71
3,4-Methylenedioxypropiophenone ≥98% 39438 50mg $245
3,4-Methylenedioxy Propiophenone TRC-M304050-5G 5g $78
3,4-Methylenedioxy Propiophenone TRC-M304050-1G 1g $73
3,4-Methylenedioxypropiophenone ≥98% CS-W017337 500mg $28

3′,4′-(Methylenedioxy)propiophenone Properties

Melting point 34-36°C
Boiling point 165-168°C 20mm
Density 1,21 g/cm3
Flash point 165-168°C/20mm
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Low-Melting Solid
color Off-White to Light Brown
BRN 165729
InChI InChI=1S/C10H10O3/c1-2-8(11)7-3-4-9-10(5-7)13-6-12-9/h3-5H,2,6H2,1H3
InChIKey RVBJGSPBFIUTTR-UHFFFAOYSA-N
SMILES C(C1=CC=C2OCOC2=C1)(=O)CC
CAS DataBase Reference 28281-49-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 79S7K6SNO8
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
Signal word  Warning
Hazard statements  H302-H315-H319-H335-H411
Precautionary statements  P233-P260-P261-P264-P270-P271-P273-P280-P301+P312-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P330-P332+P313-P337+P313-P340-P362-P391-P403-P403+P233-P405-P501
Hazard Codes  Xn
Risk Statements  33-22
Safety Statements  26-37
WGK Germany  WGK 3
RTECS  UC0440600
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Aquatic Chronic 2
REACH Registrations Active
NFPA 704
1
0 0

3′,4′-(Methylenedioxy)propiophenone price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 39438 3,4-Methylenedioxypropiophenone ≥98% 28281-49-4 10mg $71 2026-04-30 Buy
Cayman Chemical 39438 3,4-Methylenedioxypropiophenone ≥98% 28281-49-4 50mg $245 2026-04-30 Buy
TRC TRC-M304050-5G 3,4-Methylenedioxy Propiophenone 28281-49-4 5g $78 2026-06-03 Buy
TRC TRC-M304050-1G 3,4-Methylenedioxy Propiophenone 28281-49-4 1g $73 2026-06-03 Buy
ChemScene CS-W017337 3,4-Methylenedioxypropiophenone ≥98% 28281-49-4 500mg $28 2026-06-04 Buy
Product number Packaging Price Buy
39438 10mg $71 Buy
39438 50mg $245 Buy
TRC-M304050-5G 5g $78 Buy
TRC-M304050-1G 1g $73 Buy
CS-W017337 500mg $28 Buy

3′,4′-(Methylenedioxy)propiophenone Chemical Properties,Uses,Production

Description

3′,4′-(Methylenedioxy)propiophenone, also known as 3,4-(Methylenedioxy)phenyl-1-propanone (MDP1P), is a member of the benzodioxole family, which is a five-membered heterocyclic compound. This compound is a phenylpropanoid found in some plants of the genus Piper and is an isomer of 3,4-methylenedioxyphenyl-2-propanone (MDP2P).

Chemical Properties

Pale Orange Solid

Uses

Intermediate in the production of Isosafrole and Ethylone.

Definition

ChEBI: 3,4-Methylenedioxypropiophenone is a member of benzodioxoles.

Application

3′,4′-(Methylenedioxy)propiophenone is a synthetic compound with a fatty acid chain. It has been shown to have potent activity against leishmania and has been used as an intermediate in the synthesis of other drugs. 3′,4′-(Methylenedioxy)propiophenone can be synthesized by acylation reactions with chloride and acetylcholinesterase inhibition. This product also has molecular docking properties, which have been analyzed using computational methods, such as profiling and profile analysis.

Synthesis Reference(s)

Tetrahedron Letters, 23, p. 3085, 1982 DOI: 10.1016/S0040-4039(00)87539-5

274-09-9
79-03-8
28281-49-4
Synthesis of 3′,4′-(Methylenedioxy)propiophenone from 1,3-Benzodioxole and Propionyl chloride

3′,4′-(Methylenedioxy)propiophenone Preparation Products And Raw materials

Raw materials

Preparation Products

3′,4′-(Methylenedioxy)propiophenone Suppliers

Global( 141)Suppliers
Supplier Tel Email Country ProdList Advantage
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 +86-15355479329 market18@leapchem.com China 43303 58
Shandong Liteng Biotechnology Co. , Ltd.
+86-18663721413 +86-15552573001 rosy@litengpharm.com China 3279 58
Hebei Yanxi Chemical Co., Ltd.
+86-17531190177 faithe@yan-xi.com China 5838 58
Shanghai UCHEM Inc.
+86-18930848214 +86-021-56762820 sales@myuchem.com China 8899 58
Anhui Yiao New Material Technology Co., Ltd
+86-18033737140 +86-17354101231 sales1@hbganmiao.com China 217 58
Suzhou Sanyi Polymer Chemical Technology Co., Ltd.
+86-18151108777 15571922873@163.com China 99 58
Xiamen Wonderful Bio Technology Co., Ltd.
+86-13043004613 Sara@xmwonderfulbio.com China 265 58
Shaanxi Franta Biotechnology Co., Ltd
+86-13082019107 admin@flanderff.com China 234 58
Apeloa production Co.,Limited
+86-19131931000 admin@apcl.com.cn China 856 58
Shanghai Likang New Materials Co., Limited
+86-16631818819 +86-17736933208 3684455296@qq.com China 9287 58

View Lastest Price from 3′,4′-(Methylenedioxy)propiophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,4-(methylenedioxy)propiophenone pictures 2026-08-07 3,4-(methylenedioxy)propiophenone
28281-49-4
$24.00-268.00 5g 0.98 25kg Shanghai UCHEM Inc.
3,4-(METHYLENEDIOXY)PROPIOPHENONE pictures 2026-08-07 3,4-(METHYLENEDIOXY)PROPIOPHENONE
28281-49-4
$1.00 1kg 99% 100kg RongNa Biotechnology Co.,Ltd
3,4-Methylenedioxyphenyl ethyl ketone pictures 2026-07-26 3,4-Methylenedioxyphenyl ethyl ketone
28281-49-4
1gram 99.9% 20tons Shanghai Longyu Biotechnology Co., Ltd.
5-PROPIONYL-1,3-BENZODIOXOLE 1-(3,4-METHYLENEDIOXYPHENYL)-1-PROPANONE 1,3-BENZODIOXOLE-5-PROPANOYL 1-(1,3-benzodioxol-5-yl)propan-1-one 1-(benzo[d][1,3]dioxol-5-yl)propan-1-one 3',4'-(Methylenedioxy)propiophenone,98% 5-Propanoyl-1,3-benzodioxole NSC 29484 1-(Benz[d][1,3]dioxol-5-yl)propan-1-one 3,4-Methylenedioxyphenyl ethyl ketone 3,4-5(Methylenedioxy)propiophenone 1-(1,3-benzodioxol-5-yl)-1-propanon 1-(1,3-Benzodioxol-5-yl)-1-propanone 1-Propanone, 1-(1,3-benzodioxol-5-yl)- ai3-31258 1-(2H-1,3-benzodioxol-5-yl)propan-1-one 3',4'-(Methylenedioxy)propiophenone 3,4-(METHYLENEDIOXY)PROPIOPHENONE 28281-49-4 Adehydes, Acetals & Ketones Aromatics Intermediates 28281-49-4 1 ADVANCED INT.
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