17-Hydroxy-19-nor-17alpha-pregna-4,9,11-trien-20-yn-3-one
- CAS No.
- 848-21-5
- Chemical Name:
- 17-Hydroxy-19-nor-17alpha-pregna-4,9,11-trien-20-yn-3-one
- Synonyms
- R-2010;Planor;RU-2010;Ogyline;norgestrienone;Ethynyl trienolone;(17R)-17-Hydroxy-19-norpregna-4,9,11-trien-20-yn-3-one;17-Hydroxy-19-nor-17alpha-pregna-4,9,11-trien-20-yn-3-one;19-Norpregna-4,9,11-trien-20-yn-3-one, 17-hydroxy-, (17α)-;17-Hydroxy-19-nor-17alpha-pregna-4,9,11-trien-20-yn-3-one USP/EP/BP
- CBNumber:
- CB92131028
- Molecular Formula:
- C20H22O2
- Molecular Weight:
- 294.39
- MDL Number:
- MFCD00199020
- MOL File:
- 848-21-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 17-ALPHA-ETHYNYL-17-BETA-HYDROXYESTRA-4,9,11-TRIEN-3-ONE 95.00% | APN0000129 | 1MG | $679.14 |
| More product size | |||
| Melting point | 169° |
|---|---|
| alpha | D20 +63° (c = 0.5 in alc) |
| Boiling point | 376.15°C (rough estimate) |
| Density | 1.1129 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| pka | 12.76±0.40(Predicted) |
| color | Pale-yellow needles from diisopropyl ether |
| FDA UNII | 89386PYU9O |
| ATC code | G03AC07 |
17-Hydroxy-19-nor-17alpha-pregna-4,9,11-trien-20-yn-3-one Chemical Properties,Uses,Production
Uses
Norgestrienone is a progestin receptor agonist. Norgestrienone is commonly used as a progesterone compound in birth control pills and can be combined with ethinylestradiol. Norgestrienone is a click chemical. It contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Azide groups. Norgestrienone can be used in the study of hereditary angioneurotic edema[1][2].
Definition
ChEBI: Norgestrienone is a steroid. It has a role as an estrogen.
Safety Profile
Human female reproductiveeffects by implant and intravaginal routes: changes inmenstrual cycle and fertility. When heated todecomposition it emits acrid smoke and irritating fumes
References
[1] S Diaz, et al. Diaz S, Pavez M, Quinteros E, Diaz J, Robertson DN, Croxatto HB. Clinical trial with subdermal implants containing norgestrienone. Contraception. 1978 Oct;18(4):429-40. DOI:10.1016/0010-7824(78)90027-6
[2] Wu X, et al. Gestrinone combined with ultrasound-guided aspiration and ethanol injection for treatment of chocolate cyst of ovary. J Obstet Gynaecol Res. 2015 May;41(5):712-6. DOI:10.1111/jog.12612
17-Hydroxy-19-nor-17alpha-pregna-4,9,11-trien-20-yn-3-one Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34563 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9996 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39037 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 029-029-029-81148696 18161915376 | 1040@dideu.com | China | 9999 | 58 |
