1-(5-Bromo-7-azaindole)ethanone
- CAS No.
- 866545-96-2
- Chemical Name:
- 1-(5-Bromo-7-azaindole)ethanone
- Synonyms
- 3-Acetl-5-bromo-7-azaindole;1-(5-Bromo-7-azaindole)ethanone;1-(5-BROMO-1H-PYRROLO[2,3-B]PYRIDIN-3-YL)-ETHANONE;1-{5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl}ethan-1-one;Ethanone, 1-(5-broMo-1H-pyrrolo[2,3-b]pyridin-3-yl)-
- CBNumber:
- CB92485417
- Molecular Formula:
- C9H7BrN2O
- Molecular Weight:
- 239.07
- MDL Number:
- MFCD12403936
- MOL File:
- 866545-96-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone | RJB54596 | 5g | $354 |
| 1-(5-Bromo-7-azaindole)ethanone | 116010 | 1.00g | $643 |
| 1-(5-Bromo-7-azaindole)ethanone | 116010 | 5.00g | $1815 |
| 1-(5-Bromo-7-azaindole)ethanone | 116010 | 10.00g | $2632 |
| 1-(5-Bromo-7-azaindole)ethanone 97.0% | B10152 | 1g | $35 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
1-(5-Bromo-7-azaindole)ethanone price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | RJB54596 | 1-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone | 866545-96-2 | 5g | $354 | 2026-06-05 | Buy |
| Matrix Scientific | 116010 | 1-(5-Bromo-7-azaindole)ethanone | 866545-96-2 | 1.00g | $643 | 2026-05-18 | Buy |
| Matrix Scientific | 116010 | 1-(5-Bromo-7-azaindole)ethanone | 866545-96-2 | 5.00g | $1815 | 2026-05-18 | Buy |
| Matrix Scientific | 116010 | 1-(5-Bromo-7-azaindole)ethanone | 866545-96-2 | 10.00g | $2632 | 2026-05-18 | Buy |
| Synthonix | B10152 | 1-(5-Bromo-7-azaindole)ethanone 97.0% | 866545-96-2 | 1g | $35 | 2026-05-06 | Buy |
1-(5-Bromo-7-azaindole)ethanone Chemical Properties,Uses,Production
Synthesis
75-36-5
183208-35-7
866545-96-2
Step 1: Synthesis of 1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone. 5-Bromo-1H-pyrrolo[2,3-b]pyridine (2.00 g, 10.15 mmol) was added to a suspension of aluminum chloride (6.77 g, 50.75 mmol) in stirred anhydrous dichloromethane (100 mL) under nitrogen protection. The reaction mixture was stirred at room temperature for 1 h, followed by slow dropwise addition of acetyl chloride (3.61 mL, 50.75 mmol). After the dropwise addition was completed, the reaction solution was continued to be stirred for 5 hours. Upon completion of the reaction, the mixture was cooled to 0 °C in an ice bath and methanol was added slowly until the solution was clarified to quench the reaction. The reaction solution was concentrated under reduced pressure, water was added and the pH was adjusted dropwise to 4 by addition of 1 N sodium hydroxide solution.The product was extracted with ethyl acetate and the organic layer was washed with saturated potassium sodium tartrate solution to remove residual aluminum salts. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was redissolved in ethyl acetate and filtered through a silica gel bed. The filtrate was concentrated to afford 1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone as an orange solid (2.25 g, 93% yield).1H NMR (500 MHz, d6-DMSO) δ 12.70 (br s, 1H), 8.56 (d, J = 2.5 Hz, 1H), 8.55 (s, 1H), 8.40 (d , J = 2.5 Hz, 1H), 2.46 (s, 3H). Mass spectrum: m/z 238.9/240.9 (M + H+).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 24, p. 7212 - 7215
[2] Patent: US2006/30583, 2006, A1. Location in patent: Page/Page column 61-62
[3] Patent: WO2008/124849, 2008, A2. Location in patent: Page/Page column 77-78
[4] Patent: US2008/261921, 2008, A1. Location in patent: Page/Page column 141-142
[5] Patent: US2011/82138, 2011, A1. Location in patent: Page/Page column 65
1-(5-Bromo-7-azaindole)ethanone Preparation Products And Raw materials
Raw materials
Preparation Products
1-(5-Bromo-7-azaindole)ethanone Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29792 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +86-15195660023 | 3899766280@qq.com | China | 26362 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43333 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39021 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
| Chongqing jooe co., ltd | +86-15223382610 | info@jooe.com | China | 15971 | 58 |
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +86-13382787392 | sales@aeechem.com | China | 10002 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
View Lastest Price from 1-(5-Bromo-7-azaindole)ethanone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-13 | 1-(5-Bromo-7-azaindole)ethanone
866545-96-2
|
$9.80 | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- 1-(5-Bromo-7-azaindole)ethanone
866545-96-2
- $9.80
- ≥99%
- Career Henan Chemical Co
866545-96-2(1-(5-Bromo-7-azaindole)ethanone)Related Search:
1of3
