Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester
- CAS No.
- Chemical Name:
- Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester
- Synonyms
- Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester
- CBNumber:
- CB92507799
- Molecular Formula:
- C33H46N6O10
- Molecular Weight:
- 686.75254
- MDL Number:
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| Abacavir5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronicAcidMethylEster | A105030 | 10mg | $1230 |
Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester is an intermediate used in the synthesis of various Abacavir metabolites. Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Uses
An intermediate in the preparation of Abacavir metabolites
Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester Preparation Products And Raw materials
Raw materials
Preparation Products
Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Supplier | Advantage |
|---|---|
| Chemsky（shanghai）International Co.,Ltd. | 50 |
