ChemicalBook >> CAS DataBase List >>N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamidesesquifumarate
N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamidesesquifumarate
![N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamidesesquifumarate Structure](CAS/20180808/GIF/299900-84-8.gif)
- CAS No.
- 299900-84-8
- Chemical Name:
- N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamidesesquifumarate
- Synonyms
- YM-202074 sesquifumarate salt hydrate;N-cyclohexyl-6-{[(2-methoxyethyl)(methyl)amino]methyl}-N-methylthiazolo[3,2-a]benzimidazole-2-carboxamide;N-cyclohexyl-7-[[2-methoxyethyl(methyl)amino]methyl]-N-methyl-[1,3]thiazolo[3,2-a]benzimidazole-2-carboxamide;N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamidesesquifumarate
- CBNumber:
- CB92518865
- Molecular Formula:
- C26H34N4O6S
- Molecular Weight:
- 530.64
- MDL Number:
- MFCD16879020
- MOL File:
- 299900-84-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 05:36:07
| Product description | Number | Pack Size | Price |
| YM-202074 sesquifumarate salt hydrate ≥98% (HPLC) | Y1271 | 25mg | $478 |
| YM-202074 sesquifumarate salt hydrate ≥98% (HPLC) | Y1271 | 5mg | $83.3 |
| YM 202074 | 468905 | 10mg | $439 |
| YM 202074 | 468905 | 25mg | $701 |
| YM 202074 ≥99% | 257146 | 5mg | $360 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H319 |
| Precautionary statements | P301+P310+P330-P305+P351+P338 |
| Hazard Codes | T |
| Risk Statements | 25-36 |
| Safety Statements | 26-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 |
N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamidesesquifumarate price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y1271 | YM-202074 sesquifumarate salt hydrate ≥98% (HPLC) | 299900-84-8 | 25mg | $478 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y1271 | YM-202074 sesquifumarate salt hydrate ≥98% (HPLC) | 299900-84-8 | 5mg | $83.3 | 2025-07-31 | Buy |
| Usbiological | 468905 | YM 202074 | 299900-84-8 | 10mg | $439 | 2026-06-03 | Buy |
| Usbiological | 468905 | YM 202074 | 299900-84-8 | 25mg | $701 | 2026-06-03 | Buy |
| Usbiological | 257146 | YM 202074 ≥99% | 299900-84-8 | 5mg | $360 | 2026-06-03 | Buy |
N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamidesesquifumarate Chemical Properties,Uses,Production
Uses
YM 202074 is a highly selective mGluR-1 antagonist.
Biological Activity
YM-202074 is a potent and selective allosteric metabotropic glutamate receptor type 1 (mGluR1) antagonist. It bound an allosteric site of r at mGluR1 with a Ki value of 4.8 nM. It also inhibited the mGluR1-mediated inositol phosphates production in r at cerebellar granule cells with an IC50 value of 8.6 nM, while showing selectivity over mGluR(2-7).
N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamidesesquifumarate Preparation Products And Raw materials
Raw materials
Preparation Products
N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamidesesquifumarate Suppliers
Global( 13)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15815 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Merck KGaA | -- | ordercn@merckgroup.com | China | 6376 | 58 |
| Santa Cruz Biotechnology Inc | -- | scbt@scbt.com | China | 6575 | 58 |
| ApexBio Technology | -- | sales@apexbt.com | United States | 6245 | 58 |
| Beijing Zhongcheng Jinnian Technology Co., Ltd. | -- | CHINA | 2059 | 58 |
N-cyclohexyl-6-{[(2-methoxyethyl)(methyl)amino]methyl}-N-methylthiazolo[3,2-a]benzimidazole-2-carboxamide
YM-202074 sesquifumarate salt hydrate
N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamidesesquifumarate
N-cyclohexyl-7-[[2-methoxyethyl(methyl)amino]methyl]-N-methyl-[1,3]thiazolo[3,2-a]benzimidazole-2-carboxamide
299900-84-8
C22H30N4O2S15C4H4O4
C56H72N8O16S2
