I2906
- CAS No.
- 331963-29-2
- Chemical Name:
- I2906
- Synonyms
- I2906;I-2906 (I 2906;1-ET-4-HO-2-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID N'-TRIDECANOYL-HYDRAZIDE;1-ET-4-HO-2-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID N'-TRIDECANOYL-HYDRAZIDE;1-Ethyl-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinecarboxylic acid 2-(1-oxotridecyl)hydrazide;3-Quinolinecarboxylic acid, 1-ethyl-1,2-dihydro-4-hydroxy-2-oxo-, 2-(1-oxotridecyl)hydrazide
- CBNumber:
- CB92624182
- Molecular Formula:
- C25H37N3O4
- Molecular Weight:
- 443.58
- MDL Number:
- MFCD01128075
- MOL File:
- 331963-29-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| I2906 99.83% | CS-0829 | 25mg | $32 |
| I2906 99.83% | CS-0829 | 50mg | $60 |
| I2906 99.83% | CS-0829 | 100mg | $103 |
| I2906 99.83% | CS-0829 | 500mg | $357 |
| I2906 | BA1431 | 100mg | $93 |
I2906 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0829 | I2906 99.83% | 331963-29-2 | 25mg | $32 | 2026-06-04 | Buy |
| ChemScene | CS-0829 | I2906 99.83% | 331963-29-2 | 50mg | $60 | 2026-06-04 | Buy |
| ChemScene | CS-0829 | I2906 99.83% | 331963-29-2 | 100mg | $103 | 2026-06-04 | Buy |
| ChemScene | CS-0829 | I2906 99.83% | 331963-29-2 | 500mg | $357 | 2026-06-04 | Buy |
| ApexBio Technology | BA1431 | I2906 | 331963-29-2 | 100mg | $93 | 2026-05-06 | Buy |
I2906 Chemical Properties,Uses,Production
Uses
I2906 showed antimycobacterial and cytotoxic activity against mycobacterium tuberculosis. IC50 Value: Target: Antibacterial Under in vitro conditions, I2906 showed excellent antimycobacterial activities and low cytotoxicity. In a murine model infected with M. tuberculosis H37Rv, the reductions on bacterial loads of both lungs and spleen were statistically significant (p < 0.05) between I2906-treated mice and untreated controls after 4 weeks. Further, the colony-forming unit counts in the lungs were dramatically lower (p < 0.05) than that of isoniazid-treated mice by the addition of I2906 after 8 weeks. Moreover, survival rate was increased by I2906 treatment. For multidrug-resistant strain infection, bacterial counts were reduced significantly in the lungs and spleen due to I2906 treatment in comparison with data from untreated controls (p < 0.05).
References
[1] Lu, Jingning; Yue, Jun; Wu, Jing et al. In vitro and in vivo Activities of a New Lead Compound I2906 against Mycobacterium tuberculosis. Pharmacology (2010), 85(6), 365-371. DOI:10.1159/000299795
I2906 Preparation Products And Raw materials
Raw materials
Preparation Products
I2906 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7552 | 61 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2782 | 58 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9923 | 65 |
| Codow Chemical Co.,Ltd. | -- | amy@howeipharm.com | China | 6687 | 55 |
| Guangzhou QiYun Biotechnology Co., Ltd. | 020-61288194 61288195 | 505721671@qq.com | China | 3866 | 58 |
| Chengdu Huachun Technology Co., Ltd | 400-1166-196 15982826727 | cdhxsj@163.com | China | 14603 | 60 |
