5-alpha-Hydroxy- Laxogenin
- CAS No.
- 56786-63-1
- Chemical Name:
- 5-alpha-Hydroxy- Laxogenin
- Synonyms
- 5a-hydroxy laxogenin;5a-Hydroxy lxogenin;5α-hydroxy Laxogenin;DI 31;BB 16;Biobras 16;laxogenin 99%;5-alpha-Hydroxy-;5α-hydroxyLaxogenin;5a-hidroxy-Laxogenin
- CBNumber:
- CB92657041
- Molecular Formula:
- C27H42O5
- Molecular Weight:
- 446.62
- MDL Number:
- MFCD00273330
- MOL File:
- 56786-63-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5α-hydroxy Laxogenin ≥95% | 27665 | 100mg | $208 |
| 5α-hydroxy Laxogenin ≥95% | 27665 | 250mg | $494 |
| 5α-hydroxy Laxogenin ≥95% | 27665 | 500mg | $937 |
| 5α-hydroxy Laxogenin ≥95% | 27665 | 1g | $1768 |
| 5α-hydroxy Laxogenin | 27665 | 250mg | $648 |
| More product size | |||
| Melting point | 247-250 °C |
|---|---|
| Boiling point | 578.4±50.0 °C(Predicted) |
| Density | 1.21±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMF: 15 mg/ml; DMSO: 10 mg/ml |
| form | A solid |
| pka | 12.62±0.70(Predicted) |
| InChIKey | HCRGPOQBVFMZFY-YPAZECSTNA-N |
| SMILES | C1C[C@]2(C)C3CC[C@]4(C)C5[C@H](C)C6(OC[C@H](C)CC6)OC5CC4C3CC(=O)[C@@]2(O)C[C@H]1O |&1:2,7,10,15,27,30,r| |
| FDA UNII | 844KE20WT5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
5-alpha-Hydroxy- Laxogenin price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 27665 | 5α-hydroxy Laxogenin ≥95% | 56786-63-1 | 100mg | $208 | 2026-04-30 | Buy |
| Cayman Chemical | 27665 | 5α-hydroxy Laxogenin ≥95% | 56786-63-1 | 250mg | $494 | 2026-04-30 | Buy |
| Cayman Chemical | 27665 | 5α-hydroxy Laxogenin ≥95% | 56786-63-1 | 500mg | $937 | 2026-04-30 | Buy |
| Cayman Chemical | 27665 | 5α-hydroxy Laxogenin ≥95% | 56786-63-1 | 1g | $1768 | 2026-04-30 | Buy |
| Cayman Chemical | 27665 | 5α-hydroxy Laxogenin | 56786-63-1 | 250mg | $648 | 2024-03-01 | Buy |
5-alpha-Hydroxy- Laxogenin Chemical Properties,Uses,Production
Uses
5α-Hydroxy laxogenin is a synthetic derivative of a naturally occurring spirostane-type steroid, laxogenin. It is a synthetic spirostane-type steroid, which is contained in dietary supplements and advertised as anabolic agent.
Description
5α-hydroxy Laxogenin is a brassinosteroid analog and a derivative of diosgenin.Topical administration of 5α-hydroxy laxogenin (4, 8, and 12 ppm), in combination with a commercial fertilizer, increases the yield and fresh weight of endives (C. endivia).It also inhibits sodium chloride-induced decreases in the fresh weight of lettuce shoots and roots when applied topically at concentrations of 0.1 and 1 μM, as well as inhibits increases in ethylene emission at a concentration of 1 μM.
Synthesis
5874-17-9
56786-63-1
5 g (10.2 mmol) of compound 8 (CAS:5874-17-9) was taken as raw material and dissolved in 390 mL of methanol. Subsequently, a solution of 4.6 g of NaHCO3 dissolved in 60 mL of water was slowly added and the reaction mixture was stirred under reflux conditions for 3 hours. After completion of the reaction, the mixture was cooled to room temperature and left to settle. The settled reaction mixture was poured into water, filtered and dried to give 4.35 g of the target product S9 (95% yield) with a melting point of 272 °C (methanol). The structure of the product was confirmed by the following characterization: IR (KBr, cm-1): 3396 (νOH), 2953 (νCH), 1703 (νC=O), 1449 and 1380 (δCH), 1055 (νC-O), 977 (spiroketal); 1H-NMR (δ, ppm): 1.97/1.30 (m, 2H, H-1). 1.80/1.45 (m, 2H, H-2), 3.93 (m, 1H, H-3), 1.84/1.69 (m, 2H, H-4), 2.82/2.04 (m, 2H, H-7), 1.94 (m, 1H, H-8), 1.99 (m, 1H, H-9), 1.51/1.36 (m, 2H, H-11), 1.81 /1.28 (m, 2H, H-12), 1.47 (m, 1H, H-14), 1.96/1.29 (m, 2H, H-15), 4.44 (m, 1H, H-16), 1.83 (m, 1H, H-17), 0.82 (s, 3H, CH3-18), 0.83 (s, 3H, H-19), 1.90 (m, 1H H-20), 0.99 (d, 3H, CH3-21), 1.70/1.60 (m, 2H, H-23), 1.65/1.46 (m, 2H, H-24), 1.64 (m, 1H, H-25), 3.48/3.40 (m, 2H, H-26), 0.82 (d, CH3-27); 13C-NMR (δ ppm): 30.4 (C-1), 29.8 (C-2), 67.2 (C-3), 36.5 (C-4), 80.7 (C-5), 211.7 (C-6), 41.9 (C-7), 36.7 (C-8), 44.6 (C-9), 42.4 (C-10), 21.3 (C-11), 39.5 (C-12). 41.1 (c-13), 56.1 (c-14), 31.6 (c-15), 80.5 (c-16), 62.0 (c-17), 16.4 (c-18), 14.2 (c-19), 41.6 (c-20), 14.5 (c-21), 109.3 (c-22), 31.3 (c-23), 28.8 (c-24), 30.3 (c-24), 30.3 (c-24), 30.3 (c-24), 30.3 (c-24), 28.8 (c-24) 24), 30.3 (c-25), 66.9 (c-26), 17.1 (c-27).
References
[1] Molecules, 2016, vol. 21, # 8,
5-alpha-Hydroxy- Laxogenin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dingwang Technology (Wuhan) Co., Ltd. | +undefined-27-2786652399 +undefined13627115097 | market02@senwayer.com | China | 887 | 58 |
| XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 +86-18829239519 | sales06@tgybio.com | China | 898 | 58 |
| Shanghai Worldyang Chemical Co.,Ltd. | +86-021-56795779 +8613651600618 | sales@worldyachem.com | China | 967 | 58 |
| Shanghai Yunao International Trade Co., Ltd | +8617621705551 | asdf@shanghaihg.cn | China | 264 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 480 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 | info@fortunachem.com | China | 5995 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| HR Biotechnology Co.,Ltd | +8618565342020 | sales@chemhy.com | China | 110 | 58 |
View Lastest Price from 5-alpha-Hydroxy- Laxogenin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | 5-alpha-Hydroxy- Laxogenin
56786-63-1
|
1KG | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
 |
2026-07-24 | 5-alpha-Hydroxy- Laxogenin
56786-63-1
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-07-23 | 5a-Hydroxy Laxogenin
56786-63-1
|
1KG | 0.99 | 1000KG | Shaanxi Xianhe Biotech Co., Ltd |
-
- 5-alpha-Hydroxy- Laxogenin
56786-63-1
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- 5-alpha-Hydroxy- Laxogenin
56786-63-1
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 5a-Hydroxy Laxogenin
56786-63-1
- $0.00
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
