2,6-Difluorobenzoyl chloride
- CAS No.
- 18063-02-0
- Chemical Name:
- 2,6-Difluorobenzoyl chloride
- Synonyms
- FAC;FUROIC ACID;SKL1224;96.0%(T&2,6-difluoro;2-CARBOXYFURAN;PYROMUCIC ACID;AKOS BBS-00003916;ALPHA-FUROIC ACID;AKOS BBS-00003721
- CBNumber:
- CB9331536
- Molecular Formula:
- C7H3ClF2O
- Molecular Weight:
- 176.55
- MDL Number:
- MFCD00003238
- MOL File:
- 18063-02-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2,6-Difluorobenzoyl chloride 99% | 249408 | 25g | $61.1 |
| 2,6-Difluorobenzoyl chloride 99% | 249408 | 100g | $238 |
| 2,6-Difluorobenzoyl Chloride >97.0%(GC)(T) | D2798 | 25g | $149 |
| 2,6-Difluorobenzoyl chloride | FD71782 | 25g | $150 |
| 2,6-Difluorobenzoyl chloride | FD71782 | 50g | $181 |
| More product size | |||
| Melting point | 128-132 °C(lit.) |
|---|---|
| Boiling point | 72-77 °C/13 mmHg (lit.) |
| Density | 1.404 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 121 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| form | clear liquid |
| color | Colorless to Light orange to Yellow |
| Specific Gravity | 1.404 |
| Water Solubility | REACTS |
| Sensitive | Moisture Sensitive |
| BRN | 639438 |
| InChI | InChI=1S/C7H3ClF2O/c8-7(11)6-4(9)2-1-3-5(6)10/h1-3H |
| InChIKey | QRHUZEVERIHEPT-UHFFFAOYSA-N |
| SMILES | C(Cl)(=O)C1=C(F)C=CC=C1F |
| CAS DataBase Reference | 18063-02-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| NIST Chemistry Reference | 2,6-Difluorobenzoyl chloride(18063-02-0) |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS02,GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H314 | |||||||||
| Precautionary statements | P210-P233-P240-P280-P303+P361+P353-P305+P351+P338 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 36/37/38-34-10 | |||||||||
| Safety Statements | 26-36/37/39-45-28A-16 | |||||||||
| RIDADR | UN 2920 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LV1763000 | |||||||||
| F | 21 | |||||||||
| Hazard Note | Corrosive | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Eye Dam. 1 Flam. Liq. 3 Skin Corr. 1B |
|||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
2,6-Difluorobenzoyl chloride price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 249408 | 2,6-Difluorobenzoyl chloride 99% | 18063-02-0 | 25g | $61.1 | 2023-01-07 | Buy |
| Sigma-Aldrich | 249408 | 2,6-Difluorobenzoyl chloride 99% | 18063-02-0 | 100g | $238 | 2023-01-07 | Buy |
| TCI Chemical | D2798 | 2,6-Difluorobenzoyl Chloride >97.0%(GC)(T) | 18063-02-0 | 25g | $149 | 2026-04-30 | Buy |
| Biosynth | FD71782 | 2,6-Difluorobenzoyl chloride | 18063-02-0 | 25g | $150 | 2026-06-04 | Buy |
| Biosynth | FD71782 | 2,6-Difluorobenzoyl chloride | 18063-02-0 | 50g | $181 | 2026-06-04 | Buy |
2,6-Difluorobenzoyl chloride Chemical Properties,Uses,Production
Chemical Properties
CLEAR COLOURLESS TO LIGHT YELLOW LIQUID
Uses
2,6-Difluorobenzoyl chloride has been used in:
- the preparation of series of novel 2-aryl substituted 4H-3,1-benzoxazin-4-ones
- regioselective synthesis of 3,6-disubstituted-2-aminoimidazo[1,2-a]pyridine
- Friedel-Crafts acylation reaction of toluene, anisol, thioanisol, 4-phenoxyacetophenone and N,N-diacetyl-4-phenoxyaniline
Uses
Preservative, bactericide, furoates for perfume and flavoring, fumigant, textile processing, chemical intermediate.
Synthesis
Step 1: In a 250 ml three-necked flask equipped with a reflux condensing device, 2,6-difluorobenzoic acid, anhydrous KF, DMF and a small amount of catalyst were added sequentially, heated to reflux, the reaction was carried out for 8 h. The reaction was cooled, filtered, and the residue of the filtrate was washed with DMF, and the filtrate and the washings were combined, and the DMF was evaporated under reduced pressure, and washed, and filtered to obtain the intermediate product of 2,6-difluorobenzoic acid, a light yellow solid.
Step 2: In a 250 ml dry three-necked flask equipped with a reflux condensing device, add 2,6-difluorobenzoic acid, thionyl chloride and a small amount of catalyst in turn, heating to reflux, the reaction is 4h, evaporate the excess thionyl chloride, to get the product 2,6-difluorobenzoyl chloride, brownish yellow liquid.
2,6-Difluorobenzoyl chloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Didu New Materials Co. Ltd | +86-86-17392712779 +8617792793228 | 1090@dideu.com | China | 8660 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
View Lastest Price from 2,6-Difluorobenzoyl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-15 | 2,6-Difluorobenzoyl chloride
18063-02-0
|
$1.50 | 1g | 99.0% Min | 100 Tons | Shaanxi Didu New Materials Co. Ltd | |
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2020-01-09 | 2,6-Difluorobenzoyl chloride
18063-02-0
|
$5.50 | 1KG | 98%min | 1kg-100kg | Career Henan Chemical Co |
-

- 2,6-Difluorobenzoyl chloride
18063-02-0
- $1.50
- 99.0% Min
- Shaanxi Didu New Materials Co. Ltd
-

- 2,6-Difluorobenzoyl chloride
18063-02-0
- $5.50
- 98%min
- Career Henan Chemical Co






